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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Application of PPODA QT for embolization of aneurysms

    SBC: Aneuvas Technologies, Inc.            Topic: 101

    A cerebral aneurysm is an abnormal enlargement or pouch that forms from a weakened vessel segment in the brain Often going unnoticed and untreated an aneurysm can cause a sudden and catastrophic hemorrhage or stroke Approximately of patients die from an aneurysm rupture even before receiving medical attention and of patients die despite medical treatment Patients that survive typical ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Regulators of NaV Channels Novel Anti Allodynic Drug Candidates

    SBC: Regulonix            Topic: 102

    PROJECT SUMMARY Chemotherapy induced peripheral neuropathy CIPN is a common prevalence and potentially dose limiting side effect of many cancer chemotherapy drug treatment regimens Clinically CIPN presents with pain that is burning shooting or electric shock like The increase in prevalence of cancer coupled with an increase in the cancer survival rates due to chemotherapy regimens ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Enabling point of care molecular diagnostics by developing an adaptive PCR instrument and on demand kit reagents

    SBC: BIOVENTURES, INC            Topic: 172

    Because of its high sensitivity polymerase chain reaction PCR is the gold standard for the diagnosis of many infectious diseases but generally only implemented in well equipped laboratories One of the major roadblocks for expanding PCR to point of care markets is the lack of simple robust single tube PCR designs which preserve its laboratory based high sensitivity and specificity In this F ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Biomimetic Wound Healing Devices to Close Diabetic Wounds

    SBC: PROTEIN GENOMICS INC.            Topic: NIDDK

    The long term objective of this project is the synthesis and assembly of wound healing devices that mimic as closely as possible the biochemical and mechanical characteristics of healthy human skin The proposed research would focus on the synthesis of membranes containing electrospun human recombinant tropoelastin and collagen mixtures The ratios of the two molecules and the spinning condition ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Enabling point-of-care molecular diagnostics by developing an adaptive PCR instrument and on-demand kit reagents

    SBC: BIOVENTURES, INC            Topic: 172

    Because of its high sensitivitypolymerase chain reactionPCRis the gold standard for the diagnosis of many infectious diseasesbut generally only implemented in well equipped laboratoriesOne of the major roadblocks for expanding PCR to point of care markets is the lack of simplerobustsingle tube PCR designs which preserve its laboratory based high sensitivity and specificityIn this Fast Track STTR a ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Passive SPARKy-P Prostheses (Spring Ankle with Regenerative Kinetics)

    SBC: Springactive, Inc.            Topic: DHP16C007

    SpringActive Inc. collaborating with Arizona State University will design and build a spring-based, passive prosthetic ankle that stores energy in the stance phase and returns it at push-off to propel the user forward. The team will leverage experience in designing tuned spring ankles. A plantarflexion spring will allow the ankle to plantarflex smoothly and align to the ground after heel strike. ...

    STTR Phase I 2017 Department of DefenseDefense Health Program
  7. Wireless IMU Sensing for Activity Control of Ankle Prosthesis

    SBC: Springactive, Inc.            Topic: DHA17A005

    This proposal aims to develop a wireless IMU (WIMU) activity recognition system for SpringActive`s powered ankle prosthesis, Odyssey. Robust activity detection via WIMU will revolutionize the state-of-the-art in powered, lower limb prosthetics by integrating (i) bio-inspired intelligence with (ii) biomimetic mechanics into a highly-maneuverable, smart, ankle-foot prosthesis system. Odyssey is the ...

    STTR Phase I 2017 Department of DefenseDefense Health Program
  8. Alternative Methods for Creating a Sodium Guidestar

    SBC: Hart Scientific Consulting International LLC            Topic: AF17AT005

    The objective of the proposed research is to demonstrate high-power, scalable, and stable laser sources at specific wavelengths with narrow linewidth matched to the single velocity class of mesospheric atomic sodium for guide star application. The operation at tailored wavelengths, 1141 nm and 1178 nm (for 589 nm via frequency doubling) is addressed by the use of bandgap-engineered optically pumpe ...

    STTR Phase I 2017 Department of DefenseAir Force
  9. Alternative Methods for Creating a Sodium Guidestar

    SBC: TPhotonics Inc.            Topic: AF17AT005

    The purpose of this proposed research is to develop and commercialize a novel two color sodium guidestar laser operating simultaneously at 589 nm and 1141 nm. Our patented T-cavity design combined with VECSEL technology will be the basis for the guidestar development. The polychromatic laser guidestar (PLGS) system being proposed currently does not exist and would allow for the correction of atmos ...

    STTR Phase I 2017 Department of DefenseAir Force
  10. Three-sided Pyramid Wavefront Sensor for High Sensitivity Wavefront Control

    SBC: Hart Scientific Consulting International LLC            Topic: AF17AT006

    Fully develop the analytic theory of wavefront reconstruction from measurements made with a three-sided pyramid wavefront sensor (PWFS3), including the effects of variable modulation, photon and camera noise sources, and object angular extent. Carry out performance predictions of the PWFS3 through numerical modeling. Compare the sensitivity of the PWFS3 to a conventional Shack-Hartmann sensor and ...

    STTR Phase I 2017 Department of DefenseAir Force
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