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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Enabling point of care molecular diagnostics by developing an adaptive PCR instrument and on demand kit reagents

    SBC: BIOVENTURES, INC            Topic: 172

    Because of its high sensitivity polymerase chain reaction PCR is the gold standard for the diagnosis of many infectious diseases but generally only implemented in well equipped laboratories One of the major roadblocks for expanding PCR to point of care markets is the lack of simple robust single tube PCR designs which preserve its laboratory based high sensitivity and specificity In this F ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Novel Inhibitors of PSMB and PSMB for the Treatment of Multiple Myeloma

    SBC: InhiProt            Topic: 103

    Multiple myeloma is incurable hematologic malignancy with an expected median survival of years The proteasome inhibitors bortezomib carfilzomib and the recently approved ixazomib are a mainstay of current myeloma treatment Despite an initial response rate approaching to proteasome inhibitor containing combinations all patients relapse and eventually become resistant to any treatments ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Enabling point-of-care molecular diagnostics by developing an adaptive PCR instrument and on-demand kit reagents

    SBC: BIOVENTURES, INC            Topic: 172

    Because of its high sensitivitypolymerase chain reactionPCRis the gold standard for the diagnosis of many infectious diseasesbut generally only implemented in well equipped laboratoriesOne of the major roadblocks for expanding PCR to point of care markets is the lack of simplerobustsingle tube PCR designs which preserve its laboratory based high sensitivity and specificityIn this Fast Track STTR a ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Biofidelic Rat Surrogate for Blast-Induced Neurotrauma Studies

    SBC: CREARE LLC            Topic: A17AT022

    Blast-induced Traumatic Brain Injury (TBI) is a major threat to the health of military personnel serving in modern theaters. As such, the biomechanical injury pathways of TBI are and have been the focus of many animal studies. However, differences in the experimental setups across laboratories make it difficult to draw definitive conclusions from the resulting data. A tool that can accurately e ...

    STTR Phase I 2017 Department of DefenseDefense Health Program
  5. Freeze Casting of Tubular Sulfur Tolerant Materials for Solid Oxide Fuel Cells

    SBC: Millennitek, LLC            Topic: A14AT011

    Solid oxide fuel cells have long suffered from degradation due to impurities in the fuel and complexities associated with dissimilar materials and high operating temperatures.This degradation lowers the usable cell power output and requires ancillary equipment for fuel sulfur removal and reformation.A unique microstructure for the tubular anode will be produced using a novel freeze-casting techniq ...

    STTR Phase II 2017 Department of DefenseArmy
  6. Advanced Augmentor Ignition Modeling Tools

    SBC: CREARE LLC            Topic: N17AT003

    Reliable ignition is critical to the operational performance of augmented military engines. Augmentors must reliably ignite when thrust is needed or system (and pilot) safety could be compromised. Augmentor ignition is particularly challenging relative to other combustion systems because the ignition system must function over an extremely wide range of conditions. Optimizing existing igniter syste ...

    STTR Phase I 2017 Department of DefenseNavy
  7. Innovative Packaging to Achieve Extremely Light Weight Sensor Pod Systems

    SBC: Mentis Sciences, Inc.            Topic: N17AT007

    Mentis Sciences, Inc. and the University of New Hampshire will establish the feasibility, as well as identify and track the primary technical risks, of an extremely lightweight electronics pod that is capable of supporting modular sensor components. Feasibility of the pod will be established through validated modeling and simulation.The planned structural approach for the electronics pod is to use ...

    STTR Phase I 2017 Department of DefenseNavy
  8. Morphing-Duct and Twin Pumpjet Propulsion Concept Design

    SBC: CREARE LLC            Topic: N17AT019

    Existing 50-hp engines used on the Combat Rubber Raiding Craft (CRRC) do not provide the top speed, payload, and range characteristics necessary for missions requiring high speeds and low vibrations across a wide range of craft loads (e.g., light to heavy loading). Designing propulsors with high performance away from an optimum design point remains a difficult problem. Creare and our Research Inst ...

    STTR Phase I 2017 Department of DefenseNavy
  9. LWIR Fiber Bundle for Thermal Imaging in Gas Turbine Systems

    SBC: CREARE LLC            Topic: AF17AT016

    Improved temperature measurements of thermal barrier coating (TBC) components are needed for gas turbine research and development.Imaging pyrometry systems are preferred because they are non-contact and can measure the complex spatial temperature distribution on components.Measurement in the long-wave infrared (LWIR) band is required for accurate temperature measurements of modern TBCs.Fiber coupl ...

    STTR Phase I 2017 Department of DefenseAir Force
  10. Open Standard for Display Agnostic 3D Streaming (DA3DS)

    SBC: Third Dimension Technologies LLC            Topic: AF16AT07

    The Air Force has identified a need for a display agnostic common streaming model for 3D data. Third Dimension Technologies (TDT) and Oak Ridge National Laboratory (ORNL) have formed a consortium to define a 3D streaming model based on open standards for Display Agnostic 3D Streaming (DA3DS). Two factors are driving this need. The first is the dramatic increase in the collection, storage and trans ...

    STTR Phase II 2017 Department of DefenseAir Force
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