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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Soluble E NTPDase for sepsis

    SBC: Purine Pharmaceuticals Inc.            Topic: NIGMS

    SUMMARY Sepsis is a medical condition caused by an overwhelming systemic inflammatory response to infection Although the underlying infection can now be efficiently treated with antibiotics there are no effective therapies to control the organ damage caused by the inflammatory response of the host As a result sepsis is the leading cause of mortality in intensive care units and is the tenth lea ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Enabling point of care molecular diagnostics by developing an adaptive PCR instrument and on demand kit reagents

    SBC: BIOVENTURES, INC            Topic: 172

    Because of its high sensitivity polymerase chain reaction PCR is the gold standard for the diagnosis of many infectious diseases but generally only implemented in well equipped laboratories One of the major roadblocks for expanding PCR to point of care markets is the lack of simple robust single tube PCR designs which preserve its laboratory based high sensitivity and specificity In this F ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. A practical and versatile high resolution D dosimetry system for clinical use

    SBC: HEURIS INC.            Topic: 102

    Quality assurance QA is a critical component of radiation oncology that ensures both effective treatment delivery and patient safety Over the last decade dQA is now particularly important asramatic innovations in treatment delivery technologiesy have led to increasingly sophisticated and complex treatments that are difficult to adequately verify with conventional dosimetric verification system ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Telehealth Intervention for Improved Blood Pressure Control with Targeted Incentives Using New Technologies and Insights From Behavioral Economics to Increase the Effectiveness of Behavioral Change

    SBC: Wellth Inc.            Topic: NIA

    PROJECT SUMMARY ABSTRACT Hypertension or sustained systolic and diastolic blood pressure BP of and mm Hg or higher is among the most frequently encountered conditions in primary care in the U S The estimated prevalence is among all U S adults and increases with age to affect of seniors Hypertension is also the leading risk factor for cardiovascular disease global mortality ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Small Molecule Therapy for the Treatment of Heart Failure

    SBC: SUMOCOR LLC            Topic: NHLBI

    ABSTRACT The incidence of heart failure HF continues to increase in the United States despite significant advances in pharmacological therapies and novel devices There is an acute need for novel treatment strategies for heart failure A key abnormality in HF is defective handling of calcium that has been partially related to abnormal sarcoplasmic reticulum SR function in cardiac myocytes Red ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Enabling point-of-care molecular diagnostics by developing an adaptive PCR instrument and on-demand kit reagents

    SBC: BIOVENTURES, INC            Topic: 172

    Because of its high sensitivitypolymerase chain reactionPCRis the gold standard for the diagnosis of many infectious diseasesbut generally only implemented in well equipped laboratoriesOne of the major roadblocks for expanding PCR to point of care markets is the lack of simplerobustsingle tube PCR designs which preserve its laboratory based high sensitivity and specificityIn this Fast Track STTR a ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Stacked 2-D Meta-structures for Shielding High-Power Laser Radiation

    SBC: UTILITY DEVELOPMENT CORP            Topic: A17AT003

    The objective will be to investigate novel approaches using multilayered hybrid 2-dimensional nanostructures as passive coatings and evaluate their interactions with high energy lasers. This approach will be applied throughout the entire EM spectra. Simulations will be the main focus and will augment these with preliminary experiments in the visible range. These structured materials will be ...

    STTR Phase I 2017 Department of DefenseArmy
  8. Spectrum Localization for Improved Situational Awareness

    SBC: MAXENTRIC TECHNOLOGIES, LLC            Topic: AF17AT013

    There is a demand for scalable, wideband architectures that support spectrum monitoring, source localization, and emitter classification. RF spectrum is becoming increasingly congested as the number of emitters grows and their bandwidths widen. Technologies that improve the DoDs ability to create an accurate, detailed assessment of operating spectrum are critical to improving situational awarenes ...

    STTR Phase I 2017 Department of DefenseAir Force
  9. Freeze Casting of Tubular Sulfur Tolerant Materials for Solid Oxide Fuel Cells

    SBC: Millennitek, LLC            Topic: A14AT011

    Solid oxide fuel cells have long suffered from degradation due to impurities in the fuel and complexities associated with dissimilar materials and high operating temperatures.This degradation lowers the usable cell power output and requires ancillary equipment for fuel sulfur removal and reformation.A unique microstructure for the tubular anode will be produced using a novel freeze-casting techniq ...

    STTR Phase II 2017 Department of DefenseArmy
  10. Programmable Multi-Frequency Transmitter

    SBC: MAXENTRIC TECHNOLOGIES, LLC            Topic: MDA16T005

    The MaXentric/UTK team proposes the MaXPMFT, which exploits a wideband software defined radio architecture to create a transmitter with programmable output frequency. The flexible system will provide the ideal solution for current and future missile flight test telemetry needs through its compatibility with nearly all missile platforms and signals. The solution leverages recent advancements in com ...

    STTR Phase I 2017 Department of DefenseMissile Defense Agency
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