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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Enabling point of care molecular diagnostics by developing an adaptive PCR instrument and on demand kit reagents

    SBC: BIOVENTURES, INC            Topic: 172

    Because of its high sensitivity polymerase chain reaction PCR is the gold standard for the diagnosis of many infectious diseases but generally only implemented in well equipped laboratories One of the major roadblocks for expanding PCR to point of care markets is the lack of simple robust single tube PCR designs which preserve its laboratory based high sensitivity and specificity In this F ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Self expanding hydrogel for pelvic brachytherapy a novel method for vaginal packing and customized radiation therapy

    SBC: BrachyFoam, LLC            Topic: 102

    This proposal aims to develop a polymer hydrogel strategy that can be used to improve the clinical care of patients receiving brachytherapy for gynecological cancers The biocompatible hydrogel will form in situ after being injected into the vaginal space and later removed by instillation of water to soften the hydrogel for easy extraction This Phase I proposal focuses on optimizing the polymer ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Therapeutic disruption of Connexin mediated microtubule regulation to target glioblastoma cancer stem cells

    SBC: Acomhal Research, Inc.            Topic: 100

    Project Summary Glioblastoma GBM is one of the most lethal incurable human diseases Even with aggressive therapies including surgical resection followed by radiotherapy and chemotherapy using temozolomide TMZ the median survival for GBM patients is only months In fact GBM cancer cells are highly infiltrative and comprise a sub population of glioma stem cells GSCs with tumorigenic pro ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. GRIM for head and neck cancer therapy

    SBC: GlycoMantra Inc.            Topic: 102

    Project Summary Many clinical and preclinical studies demonstrated that interferons IFNs exert a superior anti tumor effect when combined with retinoids a class of vitamin A metabolites We identified a novel tumor suppressor Gene associated with Retinoid IFN induced Mortality GRIM by a genome wide knockdown strategy In our recent publication in the PNAS we have shown that GRIM g ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Lipid Enhanced Nano Sensors LENS for lead and mercury detection in water

    SBC: ZANSORS            Topic: NIEHS

    Abstract This Phase I application aims to determine the feasibility of using lipid enhanced nanosensor LENS arrays for smart phone based detection of lead Pb and mercury Hg in drinking water at concentrations above FDA allowable levels LENS arrays are composed of fluid lipid multilayer diffraction gratings on surfaces The fluid nature of these arrays has two advantages reagents can ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Knowledge and Usage of Lactation using Education and Advice from Support Network KULEA NET

    SBC: Benten Technologies Inc            Topic: NIMHD

    PROJECT SUMMARY ABSTRACT Breastfeeding has the potential to reduce health disparities associated with infant mortality and morbidity Breastfeeding rates by ethnicity in the United States show a marked disparity in African American AA women as compared to other groups Barriers to breastfeeding are complex with literature citing a lack of knowledge poor family and social support inhibiting soc ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Enabling point-of-care molecular diagnostics by developing an adaptive PCR instrument and on-demand kit reagents

    SBC: BIOVENTURES, INC            Topic: 172

    Because of its high sensitivitypolymerase chain reactionPCRis the gold standard for the diagnosis of many infectious diseasesbut generally only implemented in well equipped laboratoriesOne of the major roadblocks for expanding PCR to point of care markets is the lack of simplerobustsingle tube PCR designs which preserve its laboratory based high sensitivity and specificityIn this Fast Track STTR a ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Combat Systems of the Future

    SBC: Advanced Systems/Supportability Engineering Technologies And Tools, Inc.            Topic: N05149

    The S-351 mini-sub is a prototype of the Dry Combat Submersible (DCS). This prototype was established as a means of risk reduction prior to a full commitment to the DCS program. Both of these platforms have an operational need to transit with minimum operator fatigue safely to a pre-defined point and covertly deploy and retrieve SEALS. To meet these operational needs, these platforms require upgra ...

    STTR Phase II 2017 Department of DefenseSpecial Operations Command
  9. Thin Film Deposition of Highly Conductive Metals for Sensor Applications

    SBC: Summit Information Solutions, Inc.            Topic: A17AT001

    Summit Information Solutions, Inc. (Summit) proposes to use a mature thin film deposition technology, widely adopted by the microelectronics industry, to deposit pinhole-free thin films of copper and silver metal (< 10nm) onto oxide substrates. While there has been some success with using this thin film deposition technique to deposit these films onto metal substrates, a viable, repeatable methodo ...

    STTR Phase I 2017 Department of DefenseArmy
  10. Low-Temperature Fabrication of Flexible, High-Efficiency Perovskite Photovoltaic Modules for Energy Harvesting Applications

    SBC: Nanosonic Inc.            Topic: A17AT002

    Through the proposed STTR program, NanoSonic and Virginia Tech will fabricate flexible perovskite solar modules (12 x 12) that are capable of providing conversion efficiencies greater than 20% under AM 1.5G standard solar spectrum, and which demonstrate stability against temperatures up to 50C and relative humidity up to 80%. The photovoltaic market is dominated by crystalline silicon solar panel ...

    STTR Phase I 2017 Department of DefenseArmy
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