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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. RAPID TEST FOR TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES

    SBC: CC Technology            Topic: N/A

    DESCRIPTION (adapted from applicant's abstract): The long-term goal of this project is to develop a rapid, safe, and sensitive test for the abnormal isofomms of prion (PrP/res) proteins associated with the transmissible spongifomm encephalopathies (TSE). The Surface Enhanced Raman Immunoassay (SERIA) assay to be evaluated will facilitate testing of sample ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  2. One Step H. pylori Test--Screening and Individual Assays

    SBC: CC Technology            Topic: N/A

    The aim of this project is to demonstrate feasibility of four different types of H. pylori assays. Assays will be developed for both the H. pylori organism and its antibody. The specific goal will be to develop a test which is rapid and very-low cost for screening of populations and for clinical laboratories. H. pylori is significant as a cancer risk as it can cause two types of malignancies: gast ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  3. A NEW METHOD FOR MONITORING SPECIFIC NEUROTRANSMITTERS

    SBC: CC Technology            Topic: N/A

    DESCRIPTION (provided by applicant): The proposed research will develop two prototype analyzers, one of which will be interfaced with a perfusion probe for neurotransmitters, and their metabolites, Surface Enhanced Raman Assay (SERA) using Surface Enhanced Resonance Raman Scattering (SERRS). The first prototype will be placed in a translational researc ...

    STTR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  4. A NEW METHOD FOR MONITORING SPECIFIC NEUROTRANSMITTERS

    SBC: CC Technology            Topic: N/A

    DESCRIPTION (provided by applicant): The proposed research will develop two prototype analyzers, one of which will be interfaced with a perfusion probe for neurotransmitters, and their metabolites, Surface Enhanced Raman Assay (SERA) using Surface Enhanced Resonance Raman Scattering (SERRS). The first prototype will be placed in a translational researc ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  5. Detection of Multiple Chemical Warfare Agents

    SBC: CC Technology            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this Phase I STTR project is the development of an analytical method for the rapid detection of a variety of chemical warfare (CW) agents. A large number of methods have been used for the detection of CW agents, but they are generally not well suited for use under battlefield conditions, due to size, speed of analysis, power requirements or fragilit ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  6. N/A

    SBC: Detection Limit, Inc.            Topic: N/A

    N/A

    STTR Phase I 2000 Department of Health and Human ServicesNational Institutes of Health
  7. N/A

    SBC: Detection Limit, Inc.            Topic: N/A

    N/A

    STTR Phase II 2000 Department of Health and Human ServicesNational Institutes of Health
  8. Generation of Human Hepatocytes

    SBC: IN VIVO TECHNOLOGIES            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to produce "humanized" livers in large animal models such as sheep and pigs that can serve as a reliable source of significant numbers of functional human hepatocytes. The isolated human hepatocytes and/or "humanized" livers can be used for drug toxicity studies as well as for possible clinical use in patients with liver failure. Tra ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  9. Plasma Diagnostic for Alzheimer's Disease Pathology

    SBC: SAMARITAN PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Presently, there exists no simple minimally invasive test, such as a blood test, that can differentiate patients affected by Alzheimer's disease (AD) from healthy individuals. Our long-term goal is to develop new strategies for determining prognosis or predicting response to therapy. This will provide tools to improve clinical decision-making in the care of AD ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. SP004, a sigma-1 ligand with AchE inhibition properties

    SBC: SAMARITAN PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The acetylcholinesterase inhibitors (AchEI) are currently the most broadly used drugs to treat AIzheirmer's disease (AD). Unfortunately none of the beneficial effect lasts for more than a short two years time period, probably due to the progressive degeneration of the cholinergic neurons. This indicates that aiming at the same time at another target distinct to ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
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