Award Data

A highly sensitive 640 x 480-element flash LADAR camera will be developed that is capable of 100-Hz rates with better than 5-cm range precision. The design is based on proven readout integrated circuit (ROIC) designs, shown to have very low noise, high frame rates, and superior range resolution, and proven high gain, low noise avalanche photodiode (APD) array technology, sensitive in the 1.0- to 1 ...

Interest is rapidly growing in eye-safe solid-state lasers for range finding, LIDAR, infrared countermeasures, medicine, dentistry, and others. To address the need for compact, high efficiency lasers operating in this important spectral band, an ultra-compact turnkey, narrow-band, high-mode-quality, high-pulse-energy, and high-pulse-repetition-frequency (PRF), diode-pumped solid-state (DPSS) pulse ...

DESCRIPTION provided by applicant Atrial fibrillation AF is the most prevalent type of cardiac arrhythmia in the developed world affecting million people in the United States alone a number that is expected to double by because of population aging Current pharmacological options are ineffective which may be in part because these drugs fail to target key pathogenic mechanisms Recen ...

DESCRIPTION provided by applicant Each year million Americans go to health care providers because of vertigo dizziness or balance problems It is the second most common complaint heard in doctorandapos s offices and will occur in of the nationandapos s population at sometime in their lives From through of US adults aged years and older million Americans had ve ...

DESCRIPTION provided by applicant This proposal will assess the quantitative capabilities of surface enhanced Raman scattering SERS detection of cocaine and marijuana metabolites in urine samples Combining low cost instrumentation and novel chemical sensing provides an innovative new approach for diagnosing illicit drug use Current methods use a colorimetric indicator to screen specimens fo ...

DESCRIPTION provided by applicant Methamphetamine MA dependence is associated with long term damage to regions of the brain that control cognitive and psychiatric function One third to one half of MA dependent adults experience persistent cognitive and other psychiatric disorders up to three years or longer into remission The neuropsychiatric impairments that persist following abstinence ar ...

DESCRIPTION provided by applicant Human brain development represents a highly vulnerable time to chemical exposures because immature cells are actively undergoing differentiation into more complex cell types e g neurons astrocytes oligodendroglia to form neural circuits A major reason for this vulnerability is that neuronal differentiation requires critical time dependent changes to the ...

DESCRIPTION provided by applicant Stroke is a leading cause of morbidity and mortality in the United States However less than of patients are eligible for the current approved interventions of tissue plasminogen activator or thrombectomy We seek to develop new therapeutics to reduce the extent of damage and functional impairment resulting from ischemic injury to the brain an area of signi ...