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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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An Open-Source Platform for Inter-Network Analytics of High-Consequence Events
SBC: ANOMALEE INC. Topic: DTRA14B003Objectives and Intellectual Merit: The infrastructure of modern civilization is a set of complex systems1 that dynamically interact across multiple layers of abstraction. Researchers from many disciplines2 are designing analytical tools for predicting the global and local behaviors of these complicated, multi-layer networks. Easily usable, available (open source) and inter-operated tools are neede ...
STTR Phase I 2015 Department of DefenseDefense Threat Reduction Agency -
Non-Dispersive Reaction and Separation Processes for Pharmaceutical Synthesis
SBC: CHEMTOR, L.P. Topic: 300DESCRIPTION provided by applicant A number of pharmaceutical reactions and wash processes involve interaction between immiscible phases within reactors or extraction equipment Multi phase synthesis processes have been traditionally been carried out through dispersion of one of the phases into the other in the form of droplets Such arrangement increases the surface area of interaction thereby ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
A novel racial disparity marker for risk prediction in triple negative breast cancer patients
SBC: NOVAZOI THERANOSTICS Topic: NIMHDDESCRIPTION provided by applicant Breast cancers in African American AA women are characterized by earlier onset higher aggressiveness more extensive metastases and increased mortality rates compared to those in European American EA women This breast cancer related health disparity is partly due to the fact that AA women are more likely than EA women to develop a particularly aggressive ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Small Molecules To Inhibit PCSK9-LDLR
SBC: Small Molecule PPI Mimics LLC Topic: NHLBIDESCRIPTION provided by applicant This proposal is to prepare small molecules that will inhibit the protein protein interaction between a protein called PCSK and the LDLR receptor This is an extremely well validated target for reduction of andquot badandquot cholesterol LDL and therefore controlling coronary artery disease Orally available small molecules are the preferred therapeutic mo ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Measuring Bladder Permeability with MRI using a Novel Contrast Agent Formulation
SBC: Lipella Pharmaceuticals Inc. Topic: 400DESCRIPTION provided by applicant This project entails the development of a novel dual component MRI contrast agent formulation for the detecting permeability in the luminal surface of the urinary bladder The purpose of having such a test is ultimately to allow clinicians in certain circumstances to differentially diagnose a chronic non infectious inflammation of the urinary bladder from a ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
A Low Cost, Quantitative, Chemical Specific Device for Illicit Drug Detection
SBC: MKS Technology Topic: NIDADESCRIPTION provided by applicant This proposal will assess the quantitative capabilities of surface enhanced Raman scattering SERS detection of cocaine and marijuana metabolites in urine samples Combining low cost instrumentation and novel chemical sensing provides an innovative new approach for diagnosing illicit drug use Current methods use a colorimetric indicator to screen specimens fo ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Novel mass spectrometry methods for profiling modified RNA nucleotides in the nervous system
SBC: Ribonova Inc. Topic: NIDADESCRIPTION provided by applicant Pseudouridine is the most abundant post transcriptionally modified nucleoside found in ribonucleic acid RNA Pseudouridine is an enzymatically generated isomer of the canonical base uridine with additional hydrogen bonding capabilities and appears to lead to local structural and biochemical effects within RNAs Pseudouridine has been detected in several type ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
mTOR Substrate Phosphorylation: A New Bioassay for Therapeutics
SBC: COGNIZANCE BIOMARKERS, LLC Topic: 107DESCRIPTION provided by applicant There are a growing number of human diseases that have been linked to abnormally enhanced activation of the mammalian target of rapamycin mTOR signaling cascade a central pathway governing eukaryotic protein synthesis These include neurodevelopmental disorders associated with epilepsy autism and intellectual disability as well as cancer obesity and dia ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Neurotrophic Agents for Treating Parkinson's Disaese
SBC: SENEB BIOSCIENCES INC Topic: 102DESCRIPTION provided by applicant Parkinsonandapos s disease PD is a neurodegenerative disorder characterized by motor function and eventually cognitive decline GM depletion is validated as a therapeutic target for Parkinsonandapos s disease PD in clinical studies in which GM replacement stabilized motor function loss and may be disease modifying However GM has poor pharmacologic prop ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Blood-based diagnostics for Alzheimer's Disease
SBC: Amprion, Inc. Topic: NIADESCRIPTION provided by applicant This proposal is for a phase I II fast track project for the STTR program with the main goal to develop a blood test for Alzheimerandapos s disease AD diagnosis AD is the most common dementia in the elderly population and one of the leading causes of death in the developed world One of the main problems in AD is the lack of an early sensitive and objective ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health