You are here
Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
-
Selection and Development of a Lead Biologic for Treating Mitochondrial Disorders
SBC: CYTEGEN CORP Topic: NIAProject Summary Abstract Mitochondrial dysfunction causes mitochondrial diseases and is tightly linked to aging and neurodegenerative disorders such as Parkinsonandapos s and Alzheimerandapos sRecent discoveries support that mitochondrial dysfunction can be overcome to treat age related declineCyteGenandapos s hypothesis is that exercise induces the secretion of bloodborne proteins that act system ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
CCN3-derrived peptides to treat liver injury
SBC: BLR Bio Topic: 200Project Summary Chronic liver disease is becoming a major public health issue with estimates of up to 40% prevalence of non- alcoholic fatty liver disease (NAFLD) and 12% with non-alcoholic steatohepatitis (NASH) in the U.S. Liver disease and cirrhosis was the 12th leading cause of mortality in the U.S. in 2014. Obesity and metabolic syndrome are important causes of fatty liver disease or steatosi ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Wearable Shear Wave Tensiometry for Tracking Tendon Load during Dynamic Movement
SBC: Design Concepts, Incorporated Topic: NIAMSProject Summary The long term goal of this project is to develop a wirelesswearable system to estimate the tension in tendons of the legs during dynamic movementsTendon tension provides an estimate of muscle forcewhich is important information for understanding biomechanical behavior in all types of movementthough it has previously been difficult to measureRecent advances have shown that skin moun ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Quantitative Magnetic Resonance Imaging Phantoms
SBC: CALIMETRIX LLC Topic: NIBIBPROJECT SUMMARYThe overall goal of this Phase I proposal is to designdevelop and test the feasibility of advanced quantitative magnetic resonance imagingMRIphantoms that mimic the simultaneous presence of fatiron and fibrosisFatiron and fibrosis are three principal histological coexisting features of many important disease statesPhantoms are highly controlled test objects that accurately reflect t ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Gene Therapy for Type 1 Diabetes
SBC: Endsulin LLC Topic: NIDDKTypeDiabetes MellitusT DMis an increasingly prevalent form of diabetes in which the insulin producingcells of the pancreas are destroyed by an autoimmune attackand as a resultno endogenous insulin is producedMost often diagnosed in childrenmillion Americans suffer from T DMandnew cases are diagnosed annually worldwideT DM profoundly impacts patientshealth and quality of life due to the constant ne ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Integrated biochemical and bioinformatic technologies for accurate transcriptome-wide full-length RNA assembly.
SBC: LUCIGEN CORPORATION Topic: 172DESCRIPTION provided by applicant The human transcriptome is significantly more complex than its cognate genome due to the hundreds of thousands of possible isoforms allele specific expression issues variable RNA editing changes and differential expression patterns spanning cell types developmental stages and physiological stresses Next generation sequencing NGS platforms are fundame ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
A Low Cost, Quantitative, Chemical Specific Device for Illicit Drug Detection
SBC: MKS Technology Topic: NIDADESCRIPTION provided by applicant This proposal will assess the quantitative capabilities of surface enhanced Raman scattering SERS detection of cocaine and marijuana metabolites in urine samples Combining low cost instrumentation and novel chemical sensing provides an innovative new approach for diagnosing illicit drug use Current methods use a colorimetric indicator to screen specimens fo ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Biological treatment of bacterial keratitis
SBC: AMEBAGONE INC Topic: NDESCRIPTION provided by applicant Staphylococcus is the most common cause of infections worldwide The pathogen persists asymptomatically on human skin from which it may spread to ocular tissues and cause corneal infection When this happens corneal bacterial keratitis can occur and if not treated effectively it may lead to blindness Multi Drug Resistant MDR variants of S aureus Sa are ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Axonal Transport HTS Platform for Neurodegeneration Drug Discovery
SBC: Bellbrook Labs, LLC Topic: 106DESCRIPTION provided by applicant Neurodegenerative diseases that affect motor neurons such as PD ALS and HD represent an enormous unmet medical need that is growing with the aging population Existing treatments have little or no effect on the course of disease and patients have to cope with the loss of brain and body function for the rest of their lives Defects in the transport of organell ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Restimulating memory T cell responses in elderly by a novel, live influenza vaccine
SBC: FLUGEN INC Topic: NIAIDDESCRIPTION provided by applicant Respiratory infections with influenza viruses cause severe morbidity and mortality in humans and animals worldwide Importantly in humans the majority of morbidity and mortality following flu infection is seen in older individuals andgt year old Yet clear understanding of how aging impacts on innate immune responses and how to improve vaccine design ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health