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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Low Cost, Quantitative, Chemical Specific Device for Illicit Drug Detection

    SBC: MKS Technology            Topic: NIDA

    DESCRIPTION provided by applicant This proposal will assess the quantitative capabilities of surface enhanced Raman scattering SERS detection of cocaine and marijuana metabolites in urine samples Combining low cost instrumentation and novel chemical sensing provides an innovative new approach for diagnosing illicit drug use Current methods use a colorimetric indicator to screen specimens fo ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. A Single Cell Multi-Protein Device to Facilitate Cancer Immunotherapy

    SBC: ISOPLEXIS CORPORATION            Topic: 102

    DESCRIPTION provided by applicant The most promising immunotherapies against cancer rely upon modulating CD and various CD T cells to activate against cancers like melanoma lymphoma and leukemia However the ability for researchers to measure the secreted effector proteins per heterogeneous T cell which determine the cellular potency against the cancer is limited today This Phase ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Electric field-assisted membranes for organic solvent nanofiltration

    SBC: THERMOSOLV LLC            Topic: 300

    DESCRIPTION provided by applicant This multi phase SBIR project targets a significant problem within the mission of the National Institute of General Medical Sciences rapid size based separation of small Da molecules in bio manufacturing The aim here is to simplify and radically improve this currently multi stage and a resource intensive process Manufacturing of active pharmaceut ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Improved Protein Separations with Superficially Porous Particles

    SBC: ADVANCED MATERIALS TECHNOLOGY, INC.            Topic: 100

    DESCRIPTION provided by applicant Life sciences research and other critical bioanalytical applications would strongly benefit from faster and higher resolution liquid chromatographic HPLC separations of larger molecules including proteins peptides glycopeptides and glycans Many HPLC separations of biomedical interest such as resolution of protein mixtures require an hour or more and ma ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. High throughput laboratory X-ray illumination system for protein crystallography and screening

    SBC: SIGRAY, INC.            Topic: 100

    DESCRIPTION provided by applicant High throughput laboratory x ray illumination system for protein crystallography and screening X ray protein crystallography is the single most effective method to determine macromolecule structures such as proteins The understanding of the three dimensional structure of proteins gives key insight into their functionality and provides essential information ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. A high resolution and high DQE detector optimized for mammography using single-shot bi-directional tri-contrast imaging

    SBC: SIGRAY, INC.            Topic: NIBIB

    DESCRIPTION provided by applicant X ray tricontrast imaging provides three different modes of contrast absorption contrast the mechanism behind how conventional medical X ray imaging equipment images phase contrast which provides up to X more contrast than absorption based contrast for soft tissue and scatter contrast which provides information of features at dimensions smaller than ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Non Spherical Particles for HPLC

    SBC: ADVANCED MATERIALS TECHNOLOGY, INC.            Topic: 100

    DESCRIPTION provided by applicant Extending liquid chromatographic column technology to even higher performance levels has given rise to ultra high pressure liquid chromatography UPLC core shell particle technology and instrumental developments such as lower volumes for injector and detector hydraulics In spite of these advances there is still room for improvement in speed selectivity and ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
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