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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Advanced Tools for Mammalian Genome Engineering

    SBC: SynPloid Biotek LLC            Topic: ST13B001

    Recent advances in mammalian artificial chromosome design and engineering offer an alternative to existing methodologies for cellular bioengineering and address unmet needs to bioengineer more complex functionalities into human cells for subsequent commercialization. In this ST13B-001 application we propose to demonstrate utility of a novel chromosome-based gene delivery vehicle that is amenable t ...

    STTR Phase II 2015 Department of DefenseDefense Advanced Research Projects Agency
  2. Scaling & Supramolecular Engineering of Metal-Organic Frameworks (MOFs)

    SBC: Inmondo Tech, Inc.            Topic: A15AT014

    The emergence of metal-organic frameworks has presented an untapped potential for solving US Army individual and collective protection issues. The majority of work on MOF synthesis has been done at lab scale, yielding milligram or gram quantities. To test practical devices, scale up of MOF synthesis processes to kilogram quantities is necessary. However, most large commercial suppliers are uninte ...

    STTR Phase I 2015 Department of DefenseArmy
  3. Towed Magnetic Anomaly Detection (MAD) Aerodynamic Modeling and Simulation for Rotary Wing Platforms

    SBC: Area I, Inc.            Topic: N15AT009

    The Area-I team proposes to leverage its expertise and extensive design, analysis, and simulation tools to evaluate the design space of towed magnetic anomaly detection (MAD) systems with the goal of understanding the design trends and requirements in developing a new, lightweight rotorcraft-towed anti-submarine warfare (ASW) system that is optimized to take advantage of smaller state-of-the-art M ...

    STTR Phase I 2015 Department of DefenseNavy
  4. The Terabit Optical COMMunications (TOCOMM) System

    SBC: R-DEX Systems, Inc            Topic: AF14AT02

    ABSTRACT: R-DEX Systems proposes to develop the Terabit Optical COMMunications (TOCOMM) System to radically improve airborne Free-Space Optical (FSO) communications. TOCOMM will combine proven spatial, spectral, and polarization multiplexing, advanced coding and channel equalization, advanced optics, advanced laser communications and state-of-the-art pointing, acquisition and tracking (PAT) tech ...

    STTR Phase I 2015 Department of DefenseAir Force
  5. High-specificity affinity reagents for the detection of glycan sialylation

    SBC: GLYCOSENSORS AND DIAGNOSTICS, LLC            Topic: 300

    DESCRIPTION provided by applicant Glycans have several distinct properties that make their development as disease biomarkers appealing Firstly their location on cell surfaces makes them the first point of contact for cellular interactions and thus they are crucial in the control of normal metabolic processes and conversely they function as pathogen adhesion receptors Secondly specific gl ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Development of Isotopically Labeled Glycoproteins for use as Internal Standards

    SBC: GlycoScientific, L.L.C.            Topic: 300

    DESCRIPTION provided by applicant The ability to accurately quantitate the glycan chains attached to glycoproteins has wide ranging implications Numerous studies over the past years have demonstrated that abnormal glycosylation occurs in virtually all types of human cancers and demonstrate the potential of using glycan markers in either a diagnostic or a prognostic manner The glycosylatio ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. A Low Cost, Quantitative, Chemical Specific Device for Illicit Drug Detection

    SBC: MKS Technology            Topic: NIDA

    DESCRIPTION provided by applicant This proposal will assess the quantitative capabilities of surface enhanced Raman scattering SERS detection of cocaine and marijuana metabolites in urine samples Combining low cost instrumentation and novel chemical sensing provides an innovative new approach for diagnosing illicit drug use Current methods use a colorimetric indicator to screen specimens fo ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Manufacturing pathogen inactivated platelet lysate to treat corneal inflammation

    SBC: Cambium Medical Technologies LLC            Topic: N

    DESCRIPTION provided by applicant Ocular graft versus host disease O GVHD is a particularly severe and debilitating complication of allogeneic hematopoietic stem cell transplantation HSCT O GVHD develops in of patients with chronic GVHD Currently Restasis cyclosporine A is the only FDA approved prescription topical medication to treat O GVHD In Restasis had sales o ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Selenium-derivatized New Reagents for Nucleic Acid X-ray Crystallography

    SBC: SENA RESEARCH, INC.            Topic: NIEHS

    DESCRIPTION provided by applicant There are growing demands for D structure determination of nucleic acids and their protein complexes for understanding disease molecule level mechanisms and discovering innovative drugs X ray crystallography is one of the most direct and powerful tools for structure determination of these macromolecules and complexes However the crystallization and phase d ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Anti-CXCL13 mAb to mitigate prostate cancer health disparities

    SBC: JYANT Technologies, Inc.            Topic: NIMHD

    DESCRIPTION provided by applicant The most common metastatic site for hormone refractory prostate cancer HRPC PCa is bone While docetaxel can prolong the overall survival in patients with metastatic HRPC current treatments do not provide a cure Further complicating the matter HRPC is a disease that affects a variety of patients differently which can be problematic for physicians to prov ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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