Award Data

The Defense Threat Reduction Agency (DTRA) has been supporting research of energetic materials and incendiaries as payloads for weapons to defeat targets containing chemical and biological agents. Several universities and Navy labs have been involved in this research, and have narrowed down on a few material formulations that are efficient biocides. These formulations contain a chemical ingredient ...

With missions surrounding counterproliferation, nonproliferation and WMD reduction, the stakes for DTRA are incredibly high. Effectively conducting this work involves cooperation and coordination across a wide range of military and government organizations throughout the United States and the world. The decentralization of threats has led to an explosion in the sources and types of data needed to ...

Terrorist use of radioactive nuclear materials via nuclear and/or radiological dispersion devices (dirty bombs) is a serious threat. Therefore, it is critical to detect the proliferation of nuclear material. Critical challenges facing this objective include: (a) high sensitivity detection of signature emissions (e.g., gamma rays) from common radioactive isotopes behind shielding, and (b) cost-effe ...

At the completion of the research and development effort a Li foil multi-wire proportional counter (MWPC) neutron detector with more than 625 cm^2 of active area will be included in a portable radiation detection system. The system is expected to have an intrinsic thermal neutron detection efficiency of 55% or greater and gamma-ray rejection ratio (GRR) of 1.0x10^-8 or better. A gamma-ray spectrom ...

DESCRIPTION provided by applicant Crystallization followed by subsequent structure determination is a major step in understanding the structure function relationship of macromolecules Understanding macromolecule structure has become a key part in the development of new pharmaceuticals and is a major area of NIH research Crystallization however is also the rate limiting step despite techno ...

DESCRIPTION provided by applicant This proposal will assess the quantitative capabilities of surface enhanced Raman scattering SERS detection of cocaine and marijuana metabolites in urine samples Combining low cost instrumentation and novel chemical sensing provides an innovative new approach for diagnosing illicit drug use Current methods use a colorimetric indicator to screen specimens fo ...

DESCRIPTION provided by applicant The increasing output of new integral membrane protein IMP structures is partially due to the availability of an increasing number of chemical variables such as detergents detergent like molecules lipids and solubilizing stabilizing additives It is clear that specific combinations and concentrations of these different variables are often necessary to impr ...

DESCRIPTION provided by applicant The goal of this Phase II project is to optimize and validate a microfluidic chip based process that automates and shortens the labeling washing and collecting of human blood leukocytes WBCs for flow cytometric analysis of clinically important cell surface and intracellular markers Multi parameter flow cytometry is an increasingly powerful and widely used t ...

DESCRIPTION provided by applicant Zansors is a biosensor company with several research and product areas to commercialize evidence based healthcare solutions This proposed research is aimed at achieving objective assessment of blood alcohol concentration BAC by offering a wearable real time alcohol bio sensing device based on a bendable and stretchable lab on a patch platform invented by par ...

DESCRIPTION provided by applicant The Knee Biofeedback Rehabilitation Interface for Game based Home Therapy andquot KneeBRIGHTandquot system combines electromyography EMG biofeedback with video game therapy VGT to provide knee osteoarthritis OA patients with an engaging effective tool for conducting rehabilitation exercises at home KneeBRIGHT aims to motivate patients with knee OA to ...