Award Data

At the completion of the research and development effort a Li foil multi-wire proportional counter (MWPC) neutron detector with more than 625 cm^2 of active area will be included in a portable radiation detection system. The system is expected to have an intrinsic thermal neutron detection efficiency of 55% or greater and gamma-ray rejection ratio (GRR) of 1.0x10^-8 or better. A gamma-ray spectrom ...

DESCRIPTION provided by applicant Critically ill patients commonly arrive at an intensive care unit with anemia While blood transfusions are the standard of care with the intention to increase or maintain oxygen delivery to tissues questions have been raised about the benefit of blood transfusions particularly in non bleeding patients with moderate anemia A noninvasive measure of intracellu ...

DESCRIPTION provided by applicant This proposal will assess the quantitative capabilities of surface enhanced Raman scattering SERS detection of cocaine and marijuana metabolites in urine samples Combining low cost instrumentation and novel chemical sensing provides an innovative new approach for diagnosing illicit drug use Current methods use a colorimetric indicator to screen specimens fo ...

DESCRIPTION provided by applicant Doppler ultrasound is relied upon as the primary and often the only test used to diagnose vascular pathology Because variations in technical skill directly impact surgical referral decisions there is a strong clinical need to ensure that provides both attain and maintain skills in this procedure The problem we address is the lack of a quantitative or standar ...

DESCRIPTION provided by applicant During the process of screening for drugs with therapeutic potential often times several candidates emerge as prime candidates with similar efficacy and the choice for a lead compound is difficult to make However peopleandapos s lives and billions of dollars may rest on the choice of which compound to bring to clinical investigation and trials Since any lev ...

DESCRIPTION provided by applicant This grant will develop a novel strategy to enhance the analytical sensitivity of polymerase chain reaction PCR based detection of bacteria in samples We will commercialize the strategy in the form of a pre PCR andquot turbo chargerandquot to be marketed in conjunction with PCR based molecular diagnostic systems The current STTR project will apply this str ...

DESCRIPTION provided by applicant The primary goal of this Phase I STTR proposal is to develop a prototype of a rapid molecular diagnostics test to improve prediction of the antibiotic resistance of uropathogenic Escherichia coli by determining their clonal identity clonotype The clonotype determination will be done by detection of the presence absence of a limited number d of single ...