Award Data

The Defense Threat Reduction Agency (DTRA) has been supporting research of energetic materials and incendiaries as payloads for weapons to defeat targets containing chemical and biological agents. Several universities and Navy labs have been involved in this research, and have narrowed down on a few material formulations that are efficient biocides. These formulations contain a chemical ingredient ...

With missions surrounding counterproliferation, nonproliferation and WMD reduction, the stakes for DTRA are incredibly high. Effectively conducting this work involves cooperation and coordination across a wide range of military and government organizations throughout the United States and the world. The decentralization of threats has led to an explosion in the sources and types of data needed to ...

DESCRIPTION provided by applicant MicroRNAs miRNAs are involved in many diverse biological processes and a single miRNA can modulate the expression of hundreds of gene targets Changes in miRNA expression could have profound biological impacts leading to a variety of human diseases To date most miRNA expression profiling studies have relied on microarrays or high throughput RNA sequencing ...

DESCRIPTION provided by applicant RNA interference RNAi is a small RNA guided gene silencing process within living cells The RNAi technique is widely used in both biological research and clinical applications because it has the ability to knockdown essentially any gene of interest However one major unresolved issue in RNAi studies is non specific gene silencing It is well known that in ...

DESCRIPTION provided by applicant This proposal will assess the quantitative capabilities of surface enhanced Raman scattering SERS detection of cocaine and marijuana metabolites in urine samples Combining low cost instrumentation and novel chemical sensing provides an innovative new approach for diagnosing illicit drug use Current methods use a colorimetric indicator to screen specimens fo ...

DESCRIPTION provided by applicant The goal of this Phase II project is to optimize and validate a microfluidic chip based process that automates and shortens the labeling washing and collecting of human blood leukocytes WBCs for flow cytometric analysis of clinically important cell surface and intracellular markers Multi parameter flow cytometry is an increasingly powerful and widely used t ...

DESCRIPTION provided by applicant Zansors is a biosensor company with several research and product areas to commercialize evidence based healthcare solutions This proposed research is aimed at achieving objective assessment of blood alcohol concentration BAC by offering a wearable real time alcohol bio sensing device based on a bendable and stretchable lab on a patch platform invented by par ...

DESCRIPTION provided by applicant The Knee Biofeedback Rehabilitation Interface for Game based Home Therapy andquot KneeBRIGHTandquot system combines electromyography EMG biofeedback with video game therapy VGT to provide knee osteoarthritis OA patients with an engaging effective tool for conducting rehabilitation exercises at home KneeBRIGHT aims to motivate patients with knee OA to ...

DESCRIPTION provided by applicant Osteoarthritis OA diagnosed in over of the US population is the primary cause of musculoskeletal lower extremity disability Although there is no cure exercise remains the core treatment to manage OA regardless of age comorbidity pain severity or disability Yet many people with this condition do not engage in regular fitness and thus may resort t ...

DESCRIPTION provided by applicant Introduction The Strength and BALance SABAL program targets reduction of fall risk in older adults through fun meaningful and motivating games that incorporate evidence based exercises and automatic generation of fall risk metrics The product consisting of virtual world based gaming software and an off the shelf KinectTM sensor will be used in senior ce ...