Award Data

ABSTRACT: High power and low insertion loss WDM components will be developed. In manufacturing WDM components, solid core fibers in both polarization insensitive and polarization maintaining, will be pursued, along with photonics crystal fiber components. A range of fiber sizes and device specifications will be developed and commercially offered by Q-Peak. The component that we propose to develo ...

ABSTRACT: AdValue Photonics and University of Arizona propose to demonstrate the capability of fabricating wavelength division multiplexers (WDM) for high-power fiber laser applications. It is based on AdValue Photonics"unique fused fiber technology using large-mode-area (LMA) fibers. Both polarization-maintaining (PM) and non-PM LMA fiber WDMs will be fabricated. By the end of Phase I, two proto ...

ABSTRACT: Aurora will demonstrate on our automated fiber placement (AFP) machine that we are able to lay up composite panels that contain sacrificial fibers that can be thermally decomposed to create a microvascular network of small cavities that allow the panel to act as a heat exchanger. The AFP machine is capable of producing composite parts from mold tools as large as 9"high by 18"wide by 56 ...

ABSTRACT: Intelligence analysts need to process large amounts of text information to form an understanding of a topic of interest. The sheer amount of information can be overwhelming, so automated text analytics that assist with filtering, information extraction, and document understanding, can be highly beneficial. Deep natural language processing (NLP) applications require both structural knowl ...

ABSTRACT: Information is a national asset that must be protected. To make effective use of this asset, information sharing is critical between government agencies, with foreign government partners, and with the private sector. At the same time, in practice, balancing information sharing and information protection can be difficult. Tools are needed to address many challenges, including managing ...

ABSTRACT: Close integration of photonic devices with silicon complementary metal-oxide semiconductor (CMOS) electronics can yield significant performance improvements in many applications. The recent development of novel integrated structures in silicon including waveguides, resonators, and photodetectors will enable dramatic reductions in size, weight, and power for components implementing compl ...

DESCRIPTION (provided by applicant): The broad and long-term objective of this project is to amplify the effectiveness of vaccines without the use of chemical or biological adjuvants. We will address this objective by demonstrating the feasibility for small laser- based devices to enhance responses to intradermal vaccination. A number of investigators have shown that a promising new way to make va ...

DESCRIPTION (provided by applicant): About 3-4% of all fractures are estimated to be open fractures, where the fracture is exposed through defects in the skin and soft tissues. This equates to about 250,000 open fractures in the United States annually. Open fractures present a high risk of infection. Infection results in considerable financial burden to both the patient an healthcare system, requ ...

DESCRIPTION (provided by applicant): Cisplatin is a cornerstone therapy for a number of cancers including testicular, bladder, ovarian and lung. It is also used to treat cancers in children. In all cases there is a high incidence of acute kidney injury (AKI) that can also lead to later stage kidney damage. This risk limits its use. We have found in pilot studies that renalase, or peptide fragment ...

Project Summary / Abstract Although standard MRI techniques provide valuable structural insight, a related technique known as magnetic resonance spectroscopy (MRS) adds powerful real-time metabolic information about the tissues under study. MRS provides early detection of disease, monitoring treatment efficacy, and, in the case of cancer, a dramatic reduction in unnecessary biopsies. However, bro ...