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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Production of High Specific Activity Lutetium-177
SBC: ALPHAMED, INC Topic: N/ADESCRIPTION (provided by applicant): A separation method will be tested and evaluated to determine the feasibility of providing no carrier added lutetium-177 (Lu-177) for use in radiotherapeutic applications. An indirect method will be used to produce Lu-177 (neutron capture followed by decay). Separation of the Lu-177 from the target material will enable us to provide carrier-free Lu-177 suita ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
Novel Nanostructured Calcium Phosphate for Gene Delivery to Bone
SBC: Angstrom Medica, Inc. Topic: N/ADESCRIPTION (provided by applicant): Osteoporosis is a major and growing health care problem that responds inadequately to standard pharmacologic therapy. Because of its low bone mineral density, osteoporotic bone is mechanically weak and fractures more easily than normal bone. Moreover, fracture repair is compromised in osteoporotic patients. The work described in this Phase I STTR proposal aims ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
Design of an Automated Psoriasis Treatment System
SBC: Boston Array Technologies, Inc. Topic: N/ADESCRIPTION (provided by applicant): Up to 3 percent of populations worldwide have psoriasis. A large number of the patients with psoriasis can be treated using UV light exposure. We propose to employ a light modulating microchip based on recent Micro Electro Mechanical Systems (MEMS) technological developments to build an Automated Psoriasis Treatment System. The overall goal of Phase I a ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
Use of Self-Assembled Crystals in Cyanide Detection
SBC: CHEMMOTIF, INC. Topic: N/ADESCRIPTION (provided by applicant): ChemMotif, Inc. is developing a range of sophisticated test strips that are reliable and sufficiently sensitive to be useful in public health, environmental, and homeland security applications. The objective of this proposal is the development of an improved analytical test strip for the determination of cyanide in water at or below EPA actionable levels (0. ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
Wearable Sternal Skin Conductance Device for Hot Flashes
SBC: METIS DESIGN CORP Topic: N/AAbstract: The majority of American women transitioning through the menopause will experience hot flashes. However, safe and effective treatments for hot flashes are currently lacking. Investigation of new treatments for hot flashes has been limited by the measurement of hot flashes. Current gold standard physiologic measures of hot flashes have key limitations, including electrode design, monitor ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
Sensing Biowarfare Agents by Surface Enhanced Raman
SBC: MICROBIOTIX, INC. Topic: N/ADESCRIPTION (provided by applicant): The use of a biothreatening agent in 2001 in the United States and the ready availability of a variety of such agents highlight the need for rapid, reliable diagnostics capable of detecting and identifying these dangerous pathogens early in infection and of monitoring disease progression and therapeutic efficacy. The long-term goal of this project is to develo ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
DNA helicase and primase inhibitors for biodefense
SBC: MICROBIOTIX, INC. Topic: N/ADESCRIPTION (provided by applicant): The long-term goal of this project is to identify specific inhibitors of B. anthracis helicase and primase and develop them into novel antibiotics for bio-defense. New antibiotics based on novel chemical scaffolds are vital to the bio-defense armory because they are likely to be effective against both natural and engineered resistant forms of bio-terrorist agen ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
Size-Dependent Uptake of Tc(I)-Labeled RGD Analogs
SBC: MOLECULAR INSIGHT PHARMACEUTICALS, INC. Topic: N/ADESCRIPTION (provided by applicant): Anti-angiogenic therapy is currently one of the most active fields in cancer research. There are four basic approaches to limiting angiogenesis: blocking growth factors, inhibiting matrix proteases, directly targeting endothelial cells, and upregulating endogenous inhibitors. Although there is no simple answer to date for blocking angiogenesis, one approach now ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
A Novel Bioresorbable Septal Occluder
SBC: Nmt Medical, Inc. Topic: N/ADESCRIPTION (provided by applicant): There is a significant body of evidence that links patent foramen ovale with cryptogenic stroke. Furthermore, closure of the patent foramen ovale has been shown to reduce the risk of stroke in high-risk patients. Closure of a patent foramen ovale is currently done by percutaneous device closure using a septal occluder. This procedure has become standard for ver ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
Dose Response/Dynamics Ultrasound Mediated BBB Opening
SBC: Perfusion Technology, LLC. Topic: N/ADESCRIPTION (provided by applicant): A wide range of brain disorders are inaccessible to therapeutic agents because of the blood-brain barrier (BBB). The BBB prevents most large molecule drugs and gene preparations from entering into brain tissue. A method to safely and reversibly change the permeability of the BBB is therefore needed. Preliminary data show that ultrasound can be used to reversib ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health