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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Nitric Oxide Microfluidic Sensor

    SBC: CLINICAL SENSORS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant This Small Business Innovation Research SBIR Phase I project aims to develop a microfluidic based nitric oxide NO sensor as an early sepsis risk assessment device Sepsis causes significant strain on the U S healthcare system consuming over $ billion annually due to extended hospital stays and significant morbidity and mortality Rapid diagnosis and in ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Novel Treatment for Septicemia Targets A1 ARs

    SBC: ENDACEA, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Septicemia is a medical syndrome characterized by an overwhelming systemic response to infection that can rapidly lead to shock, organ failure and death. In the U.S. septicemia is the 10th leading cause of death overall with over 750,000 cases and 215,000 deaths each year and accounts for $17 billion in annual health care expenditures. Following its release fr ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  3. Antisense Treatment for Thalassemia. Preclinical study.

    SBC: ERCOLE BIOTECH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ultimate goal of this project is treatment of beta-thalassemia, a genetic blood disease, with antisense oligonucleotides. The project is based on the technology developed by the PI in which antisense oligonucleotides are used to restore correct functioning of a defective gene rather than, as commonly practiced, to inhibit the expression of an undesirable ge ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  4. AAV2-ASPA-Based Metabolic Intervention for Alzheimer's Disease

    SBC: ASKLEPIOS BIOPHARMACEUTICAL, INC.            Topic: NIA

    Abstract We propose to initiate preclinical development of a gene therapeutic targeted to Alzheimer's Disease. The World Health Organization's and Alzheimer's Disease International's report on Dementia (2012) recognizes that the global burden of AlzheimerDisease is forecast to worsen significantly with prevalence predicted to double every 20 years. Interventions that could prov ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Picture Me Fit: Engaging Youth in Community-Based Prevention

    SBC: PREVENTION STRATEGIES, LLC            Topic: 600

    DESCRIPTION provided by applicant Approximately one third of all U S adults and children are obese and at risk for a wide range of related chronic health conditions such as cardiovascular disease hypertension diabetes stroke osteoarthritis sleep apnea and certain types of cancer The Center for Disease Control and Prevention CDC and other expert resources recognize that although indivi ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. STTR Phase I: Surgical Glove with Shear Thickening Fluid Textile Composites for Protection Against Needlestick Injuries

    SBC: STF TECHNOLOGIES LLC            Topic: BC

    This Small Business Technology Transfer Research (STTR) Phase I project will demonstrate the technical and commercial feasibility of a puncture resistant surgical glove having areas reinforced by flexible, needle resistant nanocomposite materials made from knit textiles intercalated with shear thickening fluids (STF). STF treated textiles are a class of smart material that respond differently base ...

    STTR Phase I 2014 National Science Foundation
  7. STTR Phase I: An ultrasonic device for rapid tomographic rodent tissue and vasculature imaging

    SBC: Sonovol, Inc.            Topic: BC

    This Small Business Innovation Research (SBIR) Phase I project will build a state of the art imaging tool for rodent disease quantification using ultrasound. Hundreds of millions of dollars in the US are spent annually on preclinical drug efficacy studies, as all candidate cancer therapeutics must be screened in rodents prior to any clinical trials. Academic and industry drug researchers make use ...

    STTR Phase I 2014 National Science Foundation
  8. STTR Phase I: Robust, portable holographic imaging for label-free analysis of blood samples in the field

    SBC: M2 Photonics Innovations            Topic: BC

    This Small Business Technology Transfer (STTR) Phase I project seeks to develop a novel holographic microscope system for examining cytological samples, such as blood smears, at the point of care. Current blood cell analysis techniques require manual examination by expert technicians, resulting in a costly and time-consuming test. The project proposes to develop a compact, portable, inexpensive, a ...

    STTR Phase I 2014 National Science Foundation
  9. STTR Phase I: Integration of carbohydrate and gaseous fermentations for maximum C4 chemical yield

    SBC: ELCRITON, INC            Topic: BC

    This Small Business Technology Transfer Research Phase I project aims to enhance fermentation yield of four carbon (C4) chemicals by instating mixotrophic fermentation. In order to realize the most cost effective fermentation for commodity chemical and biofuel production, the process should achieve maximum conversion of feedstock. In carbohydrate fermentations, CO2 and H2 are commonly evolved, whi ...

    STTR Phase I 2014 National Science Foundation
  10. STTR Phase I: Production of Bio-adhesive from Animal Waste

    SBC: BIO-ADHESIVE ALLIANCE, INC            Topic: NM

    This Small Business Technology Transfer Phase I project will result in the development of a scalable prototype technology to transform swine manure into a sustainable alternative for petroleum-based construction adhesives. Thermochemical liquefaction processing of swine manure will be used to produce bio-oil which will be chemically modified to produce adhesives. Treatment of swine manure is a wor ...

    STTR Phase I 2014 National Science Foundation
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