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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Development of Small Molecules that Enhance the Delivery and the Pharmacological Effects of Oligonucleotides

    SBC: Initos Pharmaceuticals LLC            Topic: 999

    DESCRIPTION provided by applicant Antisense and siRNA oligonucleotides offer the promise of highly precise manipulation of genes involved in disease pathogenesis However despite the investment of enormous resources that promise has been fulfilled to only a limited degree A key impediment to oligonucleotide based therapeutics is the difficulty in delivering these large highly polar molecule ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Picture Me Fit: Engaging Youth in Community-Based Prevention

    SBC: Prevention Strategies, LLC            Topic: 600

    DESCRIPTION provided by applicant Approximately one third of all U S adults and children are obese and at risk for a wide range of related chronic health conditions such as cardiovascular disease hypertension diabetes stroke osteoarthritis sleep apnea and certain types of cancer The Center for Disease Control and Prevention CDC and other expert resources recognize that although indivi ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. STTR Phase I: An ultrasonic device for rapid tomographic rodent tissue and vasculature imaging

    SBC: Sonovol, Inc.            Topic: BC

    This Small Business Innovation Research (SBIR) Phase I project will build a state of the art imaging tool for rodent disease quantification using ultrasound. Hundreds of millions of dollars in the US are spent annually on preclinical drug efficacy studies, as all candidate cancer therapeutics must be screened in rodents prior to any clinical trials. Academic and industry drug researchers make use ...

    STTR Phase I 2014 National Science Foundation
  4. STTR Phase I: Robust, portable holographic imaging for label-free analysis of blood samples in the field

    SBC: M2 Photonics Innovations            Topic: BC

    This Small Business Technology Transfer (STTR) Phase I project seeks to develop a novel holographic microscope system for examining cytological samples, such as blood smears, at the point of care. Current blood cell analysis techniques require manual examination by expert technicians, resulting in a costly and time-consuming test. The project proposes to develop a compact, portable, inexpensive, a ...

    STTR Phase I 2014 National Science Foundation
  5. STTR Phase I: Production of Bio-adhesive from Animal Waste

    SBC: BIO-ADHESIVE ALLIANCE, INC            Topic: NM

    This Small Business Technology Transfer Phase I project will result in the development of a scalable prototype technology to transform swine manure into a sustainable alternative for petroleum-based construction adhesives. Thermochemical liquefaction processing of swine manure will be used to produce bio-oil which will be chemically modified to produce adhesives. Treatment of swine manure is a wor ...

    STTR Phase I 2014 National Science Foundation
  6. STTR Phase I: Multi-sine six-degree of freedom interferometry for precision stage metrology

    SBC: INSITUTEC, INC.            Topic: MI

    This Small Business Technology Transfer Phase I project will demonstrate a novel laser interferometer to provide fast and portable calibrations for ultra-precise motion control devices. This system will provide customers with a portable system that will perform nanometer-level calibrations in a fraction of the time as compared to competitive products. A system that can provide this unique capabili ...

    STTR Phase I 2014 National Science Foundation
  7. STTR Phase I: Data-Driven Decision Support Services for Emergency Department Operations

    SBC: ROUNDTABLE ANALYTICS LLC            Topic: SH

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is very significant. Suboptimal operational decision-making in emergency departments leads to inefficiencies that result in extreme patient wait-times, the diversion of ambulances to other emergency departments, wasted resources and patients who either leave before being treated or against med ...

    STTR Phase I 2015 National Science Foundation
  8. STTR Phase I: Enhancing plant genetic transformation by Agrobacterium

    SBC: Edison Agrosciences, Inc.            Topic: BT

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project is the improvement of plant genetic transformation (the introduction of new genes via biotechnology approaches). The past two decades of research and commercialization of genetically modified plants have resulted in crop species with improved agronomic traits, such as herbicide tolerance and pest resi ...

    STTR Phase I 2015 National Science Foundation
  9. Contraceptive testing for semen availability in male monkeys

    SBC: Eppin Pharma Inc            Topic: NICHD

    DESCRIPTION provided by applicant The global contraceptives market was valued at $ billion in and is expected to grow at a CAGR of from to to reach an estimated value of $ billion in An important high impact driver of this market is the prevalence of unintended pregnancies In the US there are million unintended pregnancies annually through inconsistent or ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Implantation of Bioengineered Intrinsically Innervated Internal Anal Sphincter (BioSphincter) to Treat Fecal Incontinence

    SBC: CELLF-BIO, LLC            Topic: 300

    DESCRIPTION provided by applicant We propose to bring to market a novel regenerative medicine based therapy for fecal incontinence FI FI is the recurrent uncontrolled passage of fecal material The Internal Anal Sphincter IAS is responsible for maintaining anorectal continence Function of the IAS is dependent upon the neuromuscular integrity of both the smooth muscle and the intrinsic en ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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