Award Data

Eno River Technologies and Duke University propose to develop Hybrid Boolean Network (HBN) technology for ultrafast physical random number generation. HBNs are circuits composed partly of unclocked logic elements that exhibit chaotic dynamics and clocked elements that provide readout and synchronization to the system bus. It is hypothesized that the chaotic elements amplify electronic noise in t ...

The use of novel magnesium materials with desirable properties can provide significant weight reduction and improved fuel economy in military, automobile, and aerospace applications. The proposed project aims to develop a microplasma discharge based magnesium vaporization process for manufacturing of novel magnesium alloys and composites. The method utilizes operation of a microplasma discharge in ...

HYPRES, in collaboration with MIT Lincoln Laboratory and ISQC, proposes to transition superconducting parametric amplifier technology into a robust line of products. In Phase I, we will develop three varieties of superconducting low-noise amplifiers (LNAs) in compact cryogenic microwave packages. These are two types of standing wave devices, lumped-element Josephson parametric amplifier (LJPA) and ...

Millimeter and terahertz wave imaging can image objects behind or within other objects. However, current equipment that does this quickly is expensive, and affordable equipment is prohibitively slow. Researchers at Missouri S & T have successfully developed and demonstrated several innovative millimeter wave imaging systems capable of real-time, high-resolution imaging at frequencies up to 150 G ...

Utilizing a novel solid/gas source CVD reactor designed for the growth of large area (substrates up to 4"in diameter) MoS2 single layer (SL) and multiple layer (ML) films, and leveraging already demonstrated capabilities in the growth and fabrication of 2D-FETs based on graphene and WSe2, we are proposing the growth, fabrication and testing of MoS2-based RF FETs. Utilizing a novel and optimized s ...

The objective of this proposal is to demonstrate the feasibility of producing large area, single crystal monolayer Molybdenum disulfide (MoS2) for high frequency applications. In order to be able to achieve this aim, it is necessary to work on three main components: (a) the channel material itself, (b) the gate dielectric and (c) the drain/ source contacts to the channel material. This work propo ...

DESCRIPTION (provided by applicant): This Phase I Small Business Technology Transfer (STTR) project focuses on the development of a new platform manufacturing process for large-scale preparation of monodispersed polymeric nanoparticles (NPs) suitable for biomedical applications through the use of a large-scale fiber fluidic system. Although laboratory processes for reproducible synthesis of polyme ...

Project Summary Oral ulceration is one of the most commonly encountered oral diseases, with an estimated prevalence of 4% in the USA. Managing large or multiple ulcers that are caused by diseases of unknown etiology, such as erosive lichen planus or aphthous ulcers which affect 25% of the population worldwide, is also a challenge to dentists and specialists. Ulceration of the oral mucosa can caus ...

DESCRIPTION (provided by applicant): The ultimate goal of this application is to develop a novel ex vivo purging method using myxoma virus (MYXV), a rabbit-specific poxvirus, to improve the clinical outcomes in treatment of multiple myeloma (MM). MM is aclonal plasma cell malignancy that has to date resisted essentially all therapeutic strategies. Currently, the standard of care for patients wit ...

DESCRIPTION (provided by applicant): The objective of this STTR proposal is to develop a 2-D diffusion point-of-care assay (POC) for B-type natriuretic peptide (BNP). The primary goal of the proposed work is to create a test format that will allow patientswith chronic heart failure to quantitatively self-monitor serum levels of BNP. Determination of baseline level of BNP and changes in this level ...