Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. TB Diagnostics at the Point of Care

    SBC: AKONNI BIOSYSTEMS INC.            Topic: NIAID

    ABSTRACT Tuberculosis ranks in the top ten worldwide cause of death and now ranks ahead of HIVmaking it the number one infectious disease killerPerhapsmost alarming is the global prevalence of multidrug resistant TBMDRTBand extensively drug resistant TBXDR TBmore thanof new TB cases are MDR TB andof these have XDR TBAndthe number of enrolled XDR TB cases has grown fromcountries intoinThe concern t ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Detection and Staging of Liver Fibrosis by Precise MRI (pMRI)

    SBC: INLIGHTA BIOSCIENCES L.L.C.            Topic: NIAAA

    Abstract Chronic liver injury due to alcoholmetabolic dysfunctionviral hepatitisor autoimmune disease results in liver inflammation and fibrosisLiver fibrosis will progress to cirrhosis which is estimated to affectof the world s populationThe major clinical consequences of cirrhosis are liver failure and hepatocellular carcinomaHCCboth of which increase the risk of deathAlcoholic liver diseaseALDi ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Clinical Data Intelligence & Advanced Analytics to Reduce Drug Diversion across the Care Delivery Cycle and Drug Supply Chain in Health Systems

    SBC: Invistics Corporation            Topic: NIDA

    This SBIR project will research mechanisms to detect when Health Care WorkersHCWsin hospitals steal ordivertlegal drugs either to abuse themselves or to illegally sell to othersWe focus on HCWs in hospitals because of the alarming rates of substance abuse and diversion in hospitalswith multiple studies finding roughlyof our nation s nursesanesthesiologistsand pharmacists are currently diverting dr ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Commercialization of an Ultrasound-guided Vascular Access Device

    SBC: PERCEPTIVE NAVIGATION LLC            Topic: NHLBI

    PROJECT SUMMARY Safe and reliable access to major blood vessels and internal organs will be beneficial to patients with cardiovascular and cardiothoracic diseasesAn interventional catheter with forward viewing ultrasound imaging capability will be developed to enable image guided access to blood vessels and internal organsPhaseandexperiments demonstrate feasibility of building a high resolutionfor ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Interactive Training in Emergency Operations for the Response Community

    SBC: GRYPHON SCIENTIFIC, LLC            Topic: 142

    In this Phase II SBIRGryphon Scientific proposes to develop a refresher training in form of an interactivemobile app that will allow two groups that are intermittent participants in disaster response to practice their emergency response skills after completing basic trainingThe app will target the research respondersRRwho were the focus of the Phase I project as well as thecitizen respondercommuni ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Novel genotoxicity assay incorporating the toxicogenomics biomarker TGx-28.65 with a direct digital counting

    SBC: Amelia Technologies LLC            Topic: NIEHS

    Regulatory agencies including EPAFDAECHAand EMA require thorough assessment of the health effects of chemicals present in the environment and marketplaceInterpretation of positive genotoxicity findings using the current standard in vitro testing battery is a major challenge to both industry and regulatory agenciesThese tests have high sensitivitybut suffer from low specificityleading to high rates ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Development of NanoShield for Ambient handling of labile Bio-products

    SBC: Topogen, Inc            Topic: 300

    Project Summary TopoGENin a strategic partnership with Nanoly Bioscienceproposes to develop ambient condition stable Research Use OnlyRUOproductse genzymesantibodiesand Kitsthrough the use of a syntheticsafeand biocompatible polymer encapsulation technologyNanoShieldNanoShield uses a patent protected photodegradable polyethylene glycolPEGhydrogel network to encapsulate and shield sensitive biomole ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. An add-on microscopy module for fast volumetric imaging

    SBC: MEADOWLARK OPTICS, INC.            Topic: 101

    Project Summary Microscopy with spatial light modulatorsSLMsenables use of optical techniques to simultaneously monitor and manipulate the activity of neuronal ensemblesin vitro and in vivoAs a result of successful worldwide research in this fieldsuppliers of commercial two photon microscopes feel there is extensive product potentialAs suchthree commercial microscope suppliers have licensed patent ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Caminamos: A location-based Smartphone App for Latinas to Connect with Nearby Walking Partners

    SBC: KLEIN BUENDEL, INC            Topic: 102

    Health disparities are high among LatinasThey are more likely to be overweightdiagnosed with diabetesand physically inactive compared to their non Hispanic White counterpartsThusinterventions that target improving health access and ameliorating chronic diseases among Latinas are of high public health importanceAvailable data suggest that community focused interventions produce improvements in phys ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Evaluation of National Video Directly Observed Therapy Implementation

    SBC: Emocha Mobile Health Inc.            Topic: 102

    PROJECT SUMMARYemocha Mobile HealthInc and Johns Hopkins investigators have developed a userfriendlyHIPAA compliant application for asynchronous video directly observed therapyDOTmiDOTThe miDOT platform consists of a patientfacing mobile application where patients can recordvideos of themselves taking medication at their convenience and a providerfacing web portalthat allows providers to monitor a ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
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