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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. High Efficiency Cyclone Separator for Sub-micron Particle Concentration

    SBC: MAINSTREAM ENGINEERING CORPORATION            Topic: DTRA182006

    The Radionuclide Aerosol Sampler and Analyzer (RASA) is a completely automated monitoring system that detects airborne radioactive particles and is one of the detection systems used in the U.S. and global International Monitoring System (IMS) of the Comprehensive Nuclear Test Ban Treaty Organization (CTBTO) to detect nuclear detonations. Mainstream proposes develop a high-efficiency cyclone separa ...

    SBIR Phase I 2019 Department of DefenseDefense Threat Reduction Agency
  2. Expanding Tyto Online: Earth & Space Science Quests & Sandbox for Middle School

    SBC: Immersed Games, Inc.            Topic: 91990018R0006

    In prior research and development, the developers created Tyto Online, an online multiplayer sandbox game where middle school students engage in quests to apply life science learning. This project will extend the game by developing a prototype for the Earth and Space science domain, with a prototype including quests for the Climate and Weather topic aligned to Next Generation Science Standards (NG ...

    SBIR Phase I 2018 Department of EducationInstitute of Education Sciences
  3. Topic 377: Symptom Management and Intervention Roadmaps (STaIRS)

    SBC: Carevive Systems, Inc.            Topic: NCI

    Numerous adverse symptoms are under-detected in cancer care resulting1-3 in missed opportunities for intervention; leading to poor treatment adherence, avoidable hospitalizations, and worse morbidity and survival. The IOM proposed shaking up the current symptom paradigm from reactive to proactive, personalized, technology-enabled models of symptom care as a solution to this clinical quality crisis ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. To develop a customizable sample sparing

    SBC: Grace Bio-Labs, Inc.            Topic: NIAID

    Proposes to commercially develop a customizable sample sparingeasy to usecost effectiveand highly multiplexed protein microarray platform that will simultaneously measure multipleup toimmunoglobulin isotypes subtypes in the same sample across an entire landscape of multiple antigensThe platform is designed to define different effector functions for antibodies reactive with specifically mapped epit ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. SBIR Phase 1 Diagnostics to enable malaria and neglected tropical diseases

    SBC: Hemex Health, Inc.            Topic: NIAID

    While significant progress has been made in reducing malaria prevalence and deathsmalaria elimination remains a difficult goalSelection pressures have driven malaria transmitting mosquitos to new behaviorsrendering vector control methods less effectiveMass drug administration without diagnosis can increase the risk of developing drug resistanceAdditionallyPfalciparum and Pvivax species of malaria ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Capacitive removal of PFOA and PFOS from Drinking Water

    SBC: MAINSTREAM ENGINEERING CORPORATION            Topic: 17NCER1A

    Polyfluoroalkyl and perfluoroalkyl compounds (PFCs) have been used commercially since the 1940’s due to their high level of chemical stability, almost frictionless surface or waterproofing characteristics. Elevated levels of PFCs have been linked to cancer and other health problems including reproductive and developmental risks. PFOA and PFOS are amongst the most prevalent of the PFCs with low l ...

    SBIR Phase I 2018 Environmental Protection Agency
  7. A novel biomaterial based therapy utilizing auto antigen and adjuvant for the amelioration of Type Diabetes

    SBC: ONEVAX, LLC            Topic: NIAID

    Immune mediated diseases such as type diabetes T D multiple sclerosis rheumatoid arthritis and systemic lupus erythematosis are reaching epidemic proportions in the US T D affects an estimated million Americans with more than new patients diagnosed annually resulting in roughly $ B in health care costs in the US each year T D is an autoimmune disease characterized by effector ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. An interactive App to Promote Safe and Effective use of Opioids in Young Children Postoperatively

    SBC: ARCHIE MD INC.            Topic: NIDA

    In recent years increased attention to pain in children and adolescents has led to a recent fold increase in opioid prescriptions Unsurprisingly the annual rates of analgesic related adverse drug events AR ADEs have soared to include andgt hospital admissions and hundreds of accidental overdose deaths in children and adolescents and has remained a significant problem At the heart of ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Biomaterial based delivery of Interleukin to Regulatory T Cells for the amelioration of Type Diabetes

    SBC: ONEVAX, LLC            Topic: NIAID

    Type Diabetes T D results from a breakdown of self tolerance that is characterized by immune cell mediated destruction of the insulin producing cells in the pancreas Ultimately glucose metabolism is interrupted resulting in the development of life threatening complications such as heart disease and renal failure T D affects an estimated million Americans with more than new patie ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Practical Mass Spectrometry Upgrade for Identifying Fragile Protein Modifications by ECD

    SBC: E-Msion, Inc.            Topic: 400

    The speed resolution and high mass accuracy of modern mass spectrometers have revolutionized proteomics particularly for determining fragile post translational modifications that control most cellular processes Accurate identification and quantitation of phosphorylation sites remain a major challenge in proteomics The key weakness with mass spectrometry for phospho proteomics lies in the metho ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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