Award Data

Project Abstract Concordance Health Solutions (CHS) is an Indiana company with a mission to improve patient medication adherence in partnership with pharmacists and other healthcare providers. With this SBIR grant, CHS will develop and test an innovative product, the SMARxT Med Reminder (SMR) Plus system, which will extend the capability of the inexpensive SMARxT Med Reminder cap developed with a ...

DESCRIPTION (provided by applicant): Prostate cancer (PCa) is the most diagnosed cancer among men in developed countries including the United States with significant medical cost burdens. Tremendous advances have been made in PCa screening technologies, which allow early detection and treatment. Common treatment options include radical prostatectomy, external beam radiation therapy (RT) and inters ...

DESCRIPTION (provided by applicant): The mission of Novab is to utilize the unique properties of lamprey generated Variable Lymphocyte Receptors (VLRs) to develop effective, complementary and/or superior therapeutics to those currently derived from mammalian monoclonal antibodies (mMAbs). In the current application, we seek to initiate and demonstrate proof of concept for one commercial project w ...

DESCRIPTION (provided by applicant): Treatment of peripheral pain of various origins remains a major unmet medical need, affecting tens to hundreds of millions of people nationwide at some time during their lives. Kappa-opioid agonists have been shown in peripheral pain models to be particularly efficacious but suffer from centrally mediated effects that have limited their development. Perhaps the ...

DESCRIPTION (provided by applicant): Improving Articulatory Precision in Neurologically Compromised Adults Using Audiovisual Biofeedback. One of the most frustrating impairments of neurological damage is the inability to communicate properly via the speechmodality due to weakness in the oral motor structures, also known as dysarthria. We propose to develop a Tongue Tracking System (TTS) that can p ...

DESCRIPTION (provided by applicant): Neuropathic pain management is a major unmet clinical need. Classically used medications, including opioids and non-opioids (primarily NSAIDs), have major side effects associated with their use, and many individuals donot respond to any medications. Neuropathic pain drugs with novel mechanisms of action are being sought as an alternative; however, the only succ ...

DESCRIPTION (provided by applicant): The long-term goal of this project is to develop a safe and efficacious therapeutic small molecule for treatment of acute kidney injury (AKI). AKI results from diverse insults such as sepsis, ischemia-reperfusion (I/R)or nephrotoxicant exposure and nearly half of those who develop AKI do not survive. Since treatment remains largely palliative and survival rates ...

DESCRIPTION (provided by applicant): Sinoora Inc. proposes to develop an on-chip spectral domain-optical coherence tomography (SD-OCT) system for ophthalmic applications. Phase I will concentrate on demonstrating the passive optical components of the OCT system on a single chip. The passive components include a spectrometer, coupler and an interferometer. These on- chip components will then be int ...

Project Summary / Abstract - PA-13-088 The overall goal of the proposed SBIR Phase I research is to build and begin initial evaluation of a low cost, portable retinal camera used to detect age-related macular degeneration and other retinal degenerations.Age-related macular degeneration remains the most common cause of permanent vision loss in the US and industrialized countries. The specialized i ...

DESCRIPTION (provided by applicant): I The overall goal of the proposed SBIR program is to implement and evaluate a low cost, portable retinal camera, the Digital Light Ophthalmoscope (DLO), with retinal thickness measurement functionality provided by optical coherence tomography (OCT). The combined DLO-OCT system will cost-effectively identify patients with vision-threatening macular edema for r ...