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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Screening for Alcohol-Related Liver Disease Using Breath Signatures by DMS

    SBC: Applied Nanotech, Inc.            Topic: NIAAA

    DESCRIPTION (provided by applicant): Alcohol abuse is rampant in the U.S., estimates run as high as 1 in 20 adults, and cost tens of billions of dollars in treatment and economic loss. One especially intransigent problem has been alcohol-induced organ disease such as alcoholic hepatitis and cirrhosis. These diseases can currently be diagnosed, but this requires invasive procedures such as liver bi ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. A rapid, accurate, and easy-to-use diagnostic assay for STIs

    SBC: AI BIOSCIENCES, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The aim of this application is to develop a rapid, easy-to-use, and inexpensive multi-sample diagnostic system to identify sexually transmitted infection (STI) pathogens, such as Chlamydia trachomatis (CT) and Neisseriagonorrhoeae (NG) in non-traditional healthcare settings. According to the CDC, chlamydia and gonorrhea, caused by C. trachomatis and N. gonorrho ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. A Sensitive and Serotype-Specific Dengue Diagnostic Test for Low-Resource Setting

    SBC: AI BIOSCIENCES, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Dengue is transmitted mainly by the Aedes aegypti mosquitoes which inhabit the tropics, making Dengue endemic to these areas. It is caused by four genetically and serologically related viruses, termed DENV1, DENV2, DENV3, and DENV4. Dengue infection is a leading cause of illness and death in the tropics and subtropics, including Puerto Rico and the U.S. Virgin ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Enhanced Efficacy Photodynamic Disinfection

    SBC: Lynntech Inc.            Topic: NIAID

    PROJECT SUMMARY This proposal is in response to the NIAID Advanced Technology SBIR (PA-10-123) Funding Opportunity. This Phase I feasibility study is an advanced technology project with a clearly identified product that will result in a clinically relevanttopical AM treatment modality. The award period and amount requested are guided by project needs and are in compliance with the issued guideline ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Optimization of an innate immune stimulating adjuvant for an HIV DNA vaccine

    SBC: PROFECTUS BIOSCIENCES, INC.            Topic: NIAID

    DESCRIPTION: There is a growing consensus that protection against HIV infection will require BOTH antiviral antibody responses as well as polyfunctional CD4+ and CD8+ T cells with potent lytic activity. To stimulate the breadth, potency, and rate of response required, Profectus Biosciences intends to utilize its platform technologies based on electroporation of DNA vaccines combined with genetic a ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Spiral Countercurrent Chromatography for High-throughput Natural Product Purifica

    SBC: CC Biotech LLC            Topic: NCCIH

    DESCRIPTION (provided by applicant): Recent advances in countercurrent chromatography (CCC) have created novel spiral-design separation columns that hold a very high stationary phase of all the solvent systems, such that now all molecules of any size and water solubility can be successfully separated in high-speed countercurrent chromatography. With spiral CCC there is inherent versatility, more t ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Real-time qPCR assay for detection of ALT associated telomeric C-circle DNA in bl

    SBC: Capital Biosciences, Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): The overall goal of the proposed project is to investigate the feasibility of employing real-time qPCR method for detection of telomeric C-circle DNA in peripheral blood of patients with cancers that utilize Alternative Lengthening of Telomeres (ALT) as their Telomere length Maintenance Mechanism (TMM). Telomeric C-Circle DNA has been demonstrated to be specif ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Biomarker Breast Pap Test

    SBC: SILBIOTECH, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): This Phase I research proposal is to investigate the feasibility of developing a novel Biomarker Breast PapTest for screening Nipple Aspirate Fluid (NAF) and detecting breast cancers at the tumor-in-formation stage before mammographically detectable tumors are developed. Although there is a slight decline in deaths from breast cancer in recent years, it conti ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Correcting Aberrant Splicing of the Human CD22 Gene

    SBC: RETROTHERAPY, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): B-precursor acute lymphoblastic leukemia (BPL) is the most common form of cancer in children and adolescents. This project addresses an urgent and unmet need for the treatment of aggressive, treatment refractory BPL. Two recent studies have found a deletion of CD22 exon 12 (CD22?E12) in primary leukemic cells in the vast majority of pediatric patients with poor ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Optoacoustic tomography system for image-guided cryotherapy of prostate cancer

    SBC: TOMOWAVE LABORATORIES, INC.            Topic: NCI

    Summary / Abstract The objective of this Phase-I SBIR project is to develop a novel transrectal optoacoustic-ultrasonic (OU) imaging system for guiding cryotherapy of prostate cancer via real-time monitoring of ice ball formation and temperature distribution within the area of healthy tissues adjacent to the rectal wall. The proposed system will be capable of (i) non-invasive monitoring of spatial ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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