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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Proteolytic Imaging of Remodeling Myocardium

    SBC: Micro Vide, LLC            Topic: NHLBI

    DESCRIPTIONprovided by applicantProteolytic Imaging of Remodeling Myocardium Abstract Heart attacksi emyocardial infarction or MIoccur in more thanmillion patients annuallyAdvances in interventional and pharmacological therapies have dramatically improved survival following the initial MIand patients are often surviving acute MI with more extensive myocardial injuryConsequentlythe number of patien ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. A NEW HOLOGRAPHIC 3D CAMERA FOR FUNDUS IMAGING

    SBC: CELLOPTIC            Topic: N

    A NEW HOLOGRAPHIC D CAMERA FOR FUNDUS IMAGING Abstract In the United States retinal disease is the most common cause of visual impairment with age related macular degeneration AMD and diabetic retinopathy DR being the most common retinal diseases For each of the above conditions high resolution and three dimensional D imaging of the retina retinal vasculature choroid and or retinal ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Novel noninvasive diagnostic technology for dynamic imaging of mitochondrial bioenergetics in breast cancer patients

    SBC: ROBIN MEDICAL INC            Topic: 102

    Summary Breast cancer is the second most common and the major cause of cancer related death of women in the USA The last decade has witnessed major advancement of therapeutic drugs and tools while noninvasive diagnostic imaging tools to measure interventions received much less attention Currently the mainstay of noninvasive imaging in breast cancer relies primarily on anatomic imaging Metabol ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Aminoglycosides with reduced ototoxicity

    SBC: NUBAD LLC            Topic: NIAID

    PROJECT SUMMARY Aminoglycosides are one of the cheapest and well known antibiotics in clinical use for over years but one of the major limitations in their use is their ototoxicity We are developing fast and low cost methods to develop aminoglycosides with anti ribosomal activities and reduced toxicity In this project we will identify novel aminoglycoside antibacterials that show reduced ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Multivalent Oral Vaccine against Enterotoxigenic Escherichia coli and Enteric Fevers

    SBC: PROTEIN POTENTIAL LLC            Topic: NIAID

    Enteric diseases caused by enterotoxigenic E coli ETEC strains Shigella spp and Salmonella Typhi all of which are NIAID Category B priority agents collectively affect andgt million people annually worldwide Currently there is no vaccine against ETEC or shigellosis A typhoid vaccine exists An affordable effective oral multivalent vaccine against all organisms would have enormous ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. High quality compact portable low field head MRI with ultra fast gradients

    SBC: WEINBERG MEDICAL PHYSICS, INC.            Topic: 108

    The company has shown that with by using ultra fast strong gradients inexpensive low field MRI systems can collect images that are comparable in quality signal to noise ratio resolution to conventional e g T MRI The company already has made large strides in commercializing this advantage by conducting human studies with a prototype and by attracting investors The prototype was built ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. PfSPZ Vaccines Quality Systems Manufacturing Regulatory and Clinical Quality and Data Management Support for Product Commercialization

    SBC: SANARIA INC.            Topic: NIAID

    ABSTRACT Sanaria s Plasmodium falciparum Pf sporozoite SPZ vaccines development program is receiving overwhelming global support Eleven trials of Sanaria s two primary PfSPZ vaccines which include subjects were initiated in late Tanzania U S or will start in early Kenya Ghana Equatorial Guinea EG Burkina Faso Germany and the U S These trials will assess to ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Screening the Ribosome for New Target Sites

    SBC: NUBAD LLC            Topic: NIAID

    DESCRIPTION provided by applicant Nucleic acids are avenues for drug design both as therapeutics and as targets Here we propose to establish new methods for identifying antibiotic ribosome targets and lead compounds Targeting specific RNA such as rRNA which are involved in proliferation and survival of bacteria is a promising approach We are developing fast and low cost methods to screen s ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. A small molecule integrin activator to enhance cord blood transplant

    SBC: 7 Hills Pharma LLC            Topic: NHLBI

    DESCRIPTION provided by applicant This proposal is in response to PA the parent announcement for STTR R grant applications Hematopoietic stem cell transplantation has become a preferred treatment for hematological malignancies and certain genetic disorders The use of umbilical cord blood cells as a source of hematopoietic stem cells for bone marrow transplantation has increased st ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Manufacture of aseptic purified cryopreserved Plasmodium vivax sporozoites PvSPZ Challenge for controlled human malaria infection CHMI

    SBC: SANARIA INC.            Topic: NIAID

    DESCRIPTION provided by applicant Plasmodium vivax Pv the second most important human malaria parasite causes more than million cases annually including severe fatal disease Prevention and control are challenged by emerging drug resistance and relapses from dormant liver stage parasites called hypnozoites The only therapy against relapse primaquine causes life threatening acute hemo ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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