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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. TITER ON CHIP ALTERNATIVE TO SRID FOR INFLUENZA VACCINE POTENCY DETERMINATION

    SBC: INDEVR, INC.            Topic: NIAID

    DESCRIPTION provided by applicant It is widely acknowledged that for split vaccines potency determination is often a rate limiting step The FDA approved andquot gold standardandquot potency assay for influenza hemagglutinin HA protein based vaccines is single radial immunodiffusion SRID SRID is a time and labor intensive assay often requiring days to complete and a minimum of hou ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. An HIV Vaccine Strategy Based on Priming with rVSV Expressing FLSC

    SBC: PROFECTUS BIOSCIENCES, INC.            Topic: R

    DESCRIPTION Based on the prevailing evidence we believe that a highly effective vaccine for HIV prophylaxis must induce long lasting broadly cross reactive antibody responses to envelope that exhibit antiviral activity as well as multi antigen polyfunctional CD and CD T cell responses that produce antiviral chemokines and cytokines and are possibly biased towards an effector memory phenot ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Cryopreservation of Anopheles Embryos

    SBC: SANARIA INC.            Topic: R

    DESCRIPTION provided by applicant The ideal most effective tool for eliminating Plasmodium falciparum Pf the causative agent of of all malaria deaths is a highly effective vaccine that prevents blood stage infection and thereby prevents both disease and transmission Sanariaandapos s goal is to develop and commercialize a Pf sporozoite SPZ vaccine that prevents Pf blood stage infect ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Improving Accuracy and Accessibility of Early Autism Screening

    SBC: CHADIS, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): Autism is prevalent (1 in 50 children) and impairing but early intervention has been shown to improve outcomes prompting recommendations for screening at both two year and 18 month health check-ups. Detection of autismearly is crucial but accurate screening tools have been elusive. In Phase II, a practical method of improving accuracy of M-CHAT, the most widely ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Improving Accuracy and Accessibility of Early Autism Screening

    SBC: CHADIS, INC.            Topic: 103

    DESCRIPTION provided by applicant Autism is prevalent in children and impairing but early intervention has been shown to improve outcomes prompting recommendations for screening at both two year and month health check ups Detection of autism early is crucial but accurate screening tools have been elusive In Phase II a practical method of improving accuracy of M CHAT the most widel ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Computerized Screening for Comorbidity in Adolescents with Substance or Psychiatr

    SBC: KOBAK, KENNETH A            Topic: 104

    DESCRIPTION provided by applicant This Phase II SBIR grant is a follow up to the Phase I SBIR grant andquot Computerized Screening for Comorbidity in Adolescents with Substance or Psychiatric Disorders andquot During Phase I parent and adolescent self administered computerized versions of the psychiatric interview the Kiddie Schedule for Affective Disorders and Schizophrenia KSADS were de ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Aptamer-Based Detection of Cardiac Biomarker Glycosylation States Using APT-SNAP

    SBC: Proteovista LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Aptamer Based Detection of Cardiac Biomarker Glycosylation States Using APT SNAP Arrays PIs Christopher L Warren and Mary S Ozers The presence of cardiac related biomarkers in patient biospecimens can provide important insight into diagnosis of cardiovascular disease its progression and optimal therapies for treatment Most of the cardiac biomarkers in cli ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Infant Assessment of Early Communication Risk Factors: The ISCBS (formerly ECBS)

    SBC: PAUL H BROOKES PUBLISHING CO., INC.            Topic: NIDCD

    DESCRIPTION provided by applicant Effective early intervention depends on reliable identification of risk for communication impairments as soon as possible Established infant risk factors for communication impairments include poor turn taking gestures receptive language commenting symbolic play and speech Although these risk factors can be detected by mos and reliably predict late ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Noninvasive Total Hemoglobin Monitor

    SBC: Kestrel Labs Inc            Topic: NHLBI

    DESCRIPTION provided by applicant It is a rare event when new and useful medical parameters can be added to the suite of monitoring and diagnostic tests available in a clinical setting Of particular importance is the ability to measure crucial physiological parameters or analyses in a continuous and noninvasive manner evidenced by the importance of noninvasive vital signs monitoring because it ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Recombinant antigen diagnostics for filoviruses

    SBC: CORGENIX MEDICAL CORPORATION            Topic: NIAID

    DESCRIPTION provided by applicant The proposed project will further develop marketable ELISA and lateral flow immunoassay diagnostics LFI in both monoplexed and multiplexed formats for the NIAID category A BSL filoviruses and will drive pre clinical development and validation for these diagnostics These assays will be used for diagnosis of Ebola virus EBOV Sudan virus SUDV and Marbu ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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