Award Data

To address the limitations of diagnostic equipment for chemical and biological warfare agent threats, Voxtel proposes to further develop low-cost, rapid biological-threat-reporting optical nanomaterials for a tag-track-and-locate system to consistsing of five components: 1) nanocrystal nanobeacons, a series of covert threat-functionalized optical identifiers with near-infrared through short-wave i ...

This is a Phase II project to develop and evaluate the effectiveness of a responsively designed web application, Goal Guide, that enables individuals with intellectual disabilities and autism to effectively manage self-defined goals for everyday living across personal, educational, and vocational life domains. Users will be able to easily enter goals, work with data for each goal, engage with info ...

The uremic syndrome is a disabling condition attributed to the progressive retention of solutes that would normally be excreted by the kidneys and which interact negatively with physiological systems/functions. These are broadly defined as uremic toxins. Hemodialysis treatment is prescribed for the majority of individuals in the final stages of renal failure. However, better dialysis options (leng ...

DESCRIPTION provided by applicant In this project we will develop a commercial resource for the automated analysis of brain anatomy based on MRI This product is based on the whole brain parcellation algorithm with the following unique features First it is based on a cutting edge multi atlas approach in which we will incorporate rich atlas resources from Dr Moriandapos s lab at the Johns ...

DESCRIPTION provided by applicant Improvements in pre hospital trauma life support in the past years have led to impressive enhancement in patient survival These achievements have come as the result of improved equipment transport logistics assessment treatment protocols and training of personnel in all levels of the care chain from the point of injury to th hospital One of the areas th ...

DESCRIPTION provided by applicant In an effort to reduce the use of animals for toxicity testing companies have developed in vitro skin models or equivalents to replace the Draize skin irritation test This development has been further pushed by the European Union regulation that has prohibited the use of animals for collecting toxicological data on cosmetic ingredients that began Supply ...

DESCRIPTION provided by applicant Alcohol misuse continues to pose a major burden for public health Screening and brief intervention for alcohol misuse in primary care settings has been recommended for decades and the evidence base supporting it in primary care is robust However many primary care providers do not intervene in alcohol misuse and those that do often fail to do so systematica ...

DESCRIPTION provided by applicant Monoclonal antibodies mAbs have become the leading drug class for cancer treatment and over anti neoplastic mAbs are in the biopharmaceutical pipeline Most mAb therapies must be administered in doses of mg kg resulting in per patient costs of up to $ per year The high price of mAb therapy causes a significant financial burden for patients ...

DESCRIPTION provided by applicant Both primary and metastatic liver cancer is common in the US and worldwide The standard treatment for liver cancer is liver resection where part of the liver containing the tumor is surgically removed This operation is associated with considerable blood loss typically between L Blood loss is adversely associated with patient morbidity and survival ...

DESCRIPTION provided by applicant While it is well known that the brain undergoes rapid developmental changes from birth to early childhood remarkably little is understood about the relationship between changes in brain size and composition and cognitive development Yet several potentially debilitating neurocognitive disorders are a consequence of delays or abnormalities in brain development ...