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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of Software for Automated Quantification of Brain MR Images

    SBC: ANATOMYWORKS, LLC            Topic: 108

    DESCRIPTION provided by applicant In this project we will develop a commercial resource for the automated analysis of brain anatomy based on MRI This product is based on the whole brain parcellation algorithm with the following unique features First it is based on a cutting edge multi atlas approach in which we will incorporate rich atlas resources from Dr Moriandapos s lab at the Johns ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Augmented Reality System to Teach Hemostatic Agent Use in Hemorrhage Control

    SBC: SIMQUEST INTERNATIONAL, LLC            Topic: 300

    DESCRIPTION provided by applicant Improvements in pre hospital trauma life support in the past years have led to impressive enhancement in patient survival These achievements have come as the result of improved equipment transport logistics assessment treatment protocols and training of personnel in all levels of the care chain from the point of injury to th hospital One of the areas th ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Cryopreservation of Engineered Tissue Equivalents

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: 300

    DESCRIPTION provided by applicant In an effort to reduce the use of animals for toxicity testing companies have developed in vitro skin models or equivalents to replace the Draize skin irritation test This development has been further pushed by the European Union regulation that has prohibited the use of animals for collecting toxicological data on cosmetic ingredients that began Supply ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Micro-targeted Computerized Alcohol Misuse Intervention System for Health Care

    SBC: RESEARCH CIRCLE ASSOCIATES            Topic: NIAAA

    DESCRIPTION provided by applicant Alcohol misuse continues to pose a major burden for public health Screening and brief intervention for alcohol misuse in primary care settings has been recommended for decades and the evidence base supporting it in primary care is robust However many primary care providers do not intervene in alcohol misuse and those that do often fail to do so systematica ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Evaluating Photogenotoxicity using 3D Tissue Models

    SBC: MB RESEARCH LABORATORIES, INC.            Topic: NIEHS

    DESCRIPTION provided by applicant The objective of this proposal is to focus on evaluating materials for their ability to cause photogenotoxicity Photosensitivity is a harmful reaction that occurs when drugs or chemicals in the skin or eyes cause undesirable cellular damage when exposed to UV or visible light Photogenotoxicity is used as a means to screen a material for its photocarcinoge ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Continuous Chromatography Device to Economically Purify Clinical-grade Antibodies

    SBC: Semba Biosciences Inc            Topic: 102

    DESCRIPTION provided by applicant Monoclonal antibodies mAbs have become the leading drug class for cancer treatment and over anti neoplastic mAbs are in the biopharmaceutical pipeline Most mAb therapies must be administered in doses of mg kg resulting in per patient costs of up to $ per year The high price of mAb therapy causes a significant financial burden for patients ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Electrode Arrays for Bloodless Liver Resection and Tumor Ablation

    SBC: MEDICAL ENGINEERING INNOVATIONS, LLC            Topic: 102

    DESCRIPTION provided by applicant Both primary and metastatic liver cancer is common in the US and worldwide The standard treatment for liver cancer is liver resection where part of the liver containing the tumor is surgically removed This operation is associated with considerable blood loss typically between L Blood loss is adversely associated with patient morbidity and survival ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Enabling technologies for rapid and low cost molecular diagnosticshttps://apps.era.nih.gov/grantfolder/grantfolder/viewGrantFolder.do?businessAreaCode=GM&applID=8930749&folderID=90

    SBC: Atharva LLC (dba Atharva Sciences)            Topic: 172

    DESCRIPTION provided by applicant Molecular techniques including diagnostics that require separation or identification of different sized nucleic acid sequences have remained unchanged over the last several decades and rely primarily on some form of electrophoresis Diagnostics for several human diseases such as those associated with trinucleotide repeat instability exemplified by Fragile X s ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Development of linkage-specific ubiquitin binding elements

    SBC: LIFESENSORS, INC.            Topic: 102

    DESCRIPTION provided by applicant Identification quantification and isolation of low abundance proteins from complex mixtures is at best a difficult task This is especially the case for proteins carrying a post translational modification PTM that affects their half life or regulatory properties Examples of such PTMs include phosphorylation glycosylation especially O GlcNAcylation an ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Selective inhibitors of ubiquitin E3 ligase to treat high cholesterol

    SBC: Progenra, Inc            Topic: NIEHS

    DESCRIPTION provided by applicant Hypercholesterolemia is a major risk factor in cardiovascular diseases it is estimated that andgt million individuals in the U S or one sixth of the adult population have high total cholesterol and thus twice the risk of heart disease compared to those with optimal cholesterol levels While statins are widely prescribed for cholesterol lowering their se ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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