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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of a 3-D multi-planar biopsy system using new ultrasound tomographic

    SBC: Delphinus Medical Technologies, Inc            Topic: NCI

    PROJECT SUMMARY Biopsy capability is an absolute requirement for imaging facilities planning to provide breast cancer screening services. The limitations of mammography have ushered in several other imaging technologies, such as magnetic resonance (MR), positron emission mammography, and breast specific gamma, or molecular breast imaging. However, these are all relatively expensive modalities and ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Peptide-Derived Orally-Active Kappa-Opioid Receptor Agonists for Peripheral Pain

    SBC: HALIMED PHARMACEUTICALS, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): Treatment of peripheral pain of various origins remains a major unmet medical need, affecting tens to hundreds of millions of people nationwide at some time during their lives. Kappa-opioid agonists have been shown in peripheral pain models to be particularly efficacious but suffer from centrally mediated effects that have limited their development. Perhaps the ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Using Technology to Improve Clinical Counseling of Adolescent Risky Behaviors

    SBC: POSSIBILITIES FOR CHANGE LLC            Topic: NIDA

    DESCRIPTION (provided by applicant): The goal of this SBIR is to develop an innovative adolescent primary health care delivery model for use in primary care that overcomes barriers of health care provider time, skill and teen engagement when providing effective tobacco use reduction counseling. This will be achieved by creating a web-based counseling module that will provide interactive, technolog ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Microfabricated Cochlear Electrode Arrays

    SBC: MEMStim LLC            Topic: NIDCD

    DESCRIPTION (provided by applicant): In the USA, about 36 million adults suffer from hearing loss and three out of every 1,000 children are born deaf or hard-of-hearing. When conventional hearing aids provide no appreciable benefit, implantable electronicdevices using electrode arrays inside the cochlea are a viable solution. With these cochlear implants, the profoundly deaf achieve reasonable wor ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Engineered Neurotensin Fragments Targeting Neuropathic Pain

    SBC: JT Pharmaceuticals, Inc.            Topic: NIDCR

    DESCRIPTION (provided by applicant): Neuropathic pain management is a major unmet clinical need. Classically used medications, including opioids and non-opioids (primarily NSAIDs), have major side effects associated with their use, and many individuals donot respond to any medications. Neuropathic pain drugs with novel mechanisms of action are being sought as an alternative; however, the only succ ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Advanced Bactericidal Urinary Catheters Based on Electromodulated Nitric Oxide Release

    SBC: BIOCREDE INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): We propose a completely new, low cost and robust bactericidal urinary 100% silicone Foley catheter with a gt3-6 month shelf-life, that will utilize electromodulated delivery of nitric oxide (NO) for up to 45-60 d to serve as a potent antimicrobial/antibiofilm agent. The first generation device will possess a stable inorganic nitrit salt reservoir within on lume ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a lasmiditan analogue for treatment of acute kidney injury

    SBC: Mitohealth, Inc            Topic: NIDDK

    DESCRIPTION (provided by applicant): The long-term goal of this project is to develop a safe and efficacious therapeutic small molecule for treatment of acute kidney injury (AKI). AKI results from diverse insults such as sepsis, ischemia-reperfusion (I/R)or nephrotoxicant exposure and nearly half of those who develop AKI do not survive. Since treatment remains largely palliative and survival rates ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Therapeutic Use of mTOT Modulators in Polycystic Kidney Disease

    SBC: Metabolic Solutions Development Company, LLC            Topic: NIDDK

    ? DESCRIPTION (provided by applicant): Polycystic kidney disease (PKD) is a term applied to a group of inherited disorders characterized by the presence of cysts in the kidney although multiple organs are typically affected. Renal pathologies found inessentially all forms of PKD include increased fluid secretion, matrix remodeling, cellular proliferation, and apoptosis, with a altered differen ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Lessons from Nature: Antifreeze Glycolipids for Cryopreservation of Mammalian Cel

    SBC: Cell & Tissue Systems, Inc.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Storage of cells for many researchers simply involves addition of 10% DMSO or similar cryoprotectants to cells in suspension, putting them in cryovials and slow cooling to subzero temperaturesf and storage in a mechanical or nitrogen cooled freezer or dewar. As long as viable cells are present upon thawing, cell yield may be a secondary consideration due to the ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Selectively Absorbable Surgical Mesh for Hernia Repair

    SBC: POLY-MED, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Hernia repair is one of the most frequently performed surgical operations in the United States with approximately 800,000 procedures performed annually. The vast majority of these repairs employ a tension- free repairtechnique which involves the use of synthetic surgical meshes. Existing mesh technology is designed to be of high strength to produce a perceive ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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