Award Data

The project will create an affordable system to monitor adolescent athletes in contact sports to identify individuals at risk for traumatic brain injury from continual sub-concussive impacts. The need is to reduce the risk of long term brain injury by providing tools to tell when it's risky/safe to play and find areas where strength training and technique may reduce risk on an individual level. Th ...

Innovative Design Labs (IDL), in collaboration with the Rehabilitation Institute of Chicago (RIC), proposes to create a system for the sensing and control of stand-to-sit motions of a wearable bionics suit. Recent research found that 3.86 million Americans require wheelchairs and the number has been increasing annually by an average annual rate of 5.9% a year. While wheelchairs provide freedom all ...

Perfluorooctanesulfonic acid (PFOS) is an anionic surfactant species that is a member of a large family of ubiquitous and emerging environmental contaminants known as perfluoro chemicals (PFCs). Soil and groundwater contamination by PFCs have been caused by legal emissions from industrial manufacturers (carpets, lubricants, paints, packaging, cookware), protectant spray consumer products, polymer ...

DESCRIPTION (provided by applicant): An estimated 5.4 million Americans had Alzheimer's disease in 2012 and a 50% increase in this number is expected by 2030. The majority of these patients (70%) will live at home where they receive 75% of their care frominformal caregivers, unpaid individuals such as family members, friends, and neighbors. These caregivers provide valuable services, often a ...

DESCRIPTION (provided by applicant): Advanced Medical Electronics (AME) and our partners propose a minimally-invasive system for continuous monitoring of potassium. Measurement of blood levels of potassium is important in clinical medicine. Abnormalities of potassium, common in heart and kidney disease, can be aggravated by many medications used to treat these disorders leading to arrhythmias and ...

DESCRIPTION (provided by applicant): Fungal infections, particularly in immunocompromised patients, are a serious and growing problem. Although antifungal therapeutics have improved greatly, failures and relapse are common. Aspergillus fumigatus is a primary cause of these infections in several patient populations: transplants, leukemics, genetic deficiencies such as chronic granulomatous disease ...

DESCRIPTION (provided by applicant): In orthopedic surgery, surgeons have to handle not only bone but also the surrounding soft tissue, including muscle, fascia, tendon, ligament and capsule. Successful handling of these tissues is often the key to high reproducibility, good soft tissue healing, and restoration of overall function. However, there are no widely used, robust methods for intra-opera ...

DESCRIPTION (provided by applicant): In the U.S., prostate cancer is the second leading cause of cancer death in men, and one in six men will eventually develop prostate cancer during his lifetime. Currently, the prostate specific antigen test and digitalrectal examination are the most predominant used tools for prostate cancer detection, but both methods have low specificity and poorly predict t ...

DESCRIPTION (provided by applicant): This SBIR project brings together the skills and resources of laboratories at Scion Cardio-Vascular Inc. (Scion C-V), Loma Linda University, and North Carolina State University to advance a new signaling molecule treatment for superficial bladder cancer. This treatment delivers the cytokine Interleukin 12 (IL-12) to the bladder wall using Scion C-V's muco ...

DESCRIPTION (provided by applicant): Treatment of peripheral pain of various origins remains a major unmet medical need, affecting tens to hundreds of millions of people nationwide at some time during their lives. Kappa-opioid agonists have been shown in peripheral pain models to be particularly efficacious but suffer from centrally mediated effects that have limited their development. Perhaps the ...