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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Commercializing the Effective K-3 Assessment to Instruction (A2i) Intervention to Reduce Cost and to Scale Access to the Benefit of More Students

    SBC: Learning Ovations, Inc.            Topic: N/A

    Purpose: Students who fail to achieve proficient levels of literacy are at increased risk for grade retention, referral to special education, and dropping out of high school. The kindergarten through 3rd grade years are particularly important for students to gain a strong foundation in reading as those who continue to struggle with reading are significantly less likely to achieve reading proficien ...

    SBIR Phase I 2014 Department of Education
  2. Commercializing the Effective K-3 Assessment to Instruction (A2i) Intervention to Reduce Cost and to Scale Access to the Benefit of More Students

    SBC: Learning Ovations, Inc.            Topic: N/A

    Purpose: Students who fail to achieve proficient levels of literacy are at increased risk for grade retention, referral to special education, and dropping out of high school. The kindergarten through 3rd grade years are particularly important for students to gain a strong foundation in reading as those who continue to struggle with reading are significantly less likely to achieve reading proficien ...

    SBIR Phase II 2014 Department of Education
  3. Low-Cost, Regenerable Air Filter for Efficient Gaseous Pollutants Removal

    SBC: Precision Combustion, Inc.            Topic: D

    Precision Combustion, Inc. (PCI) proposes to develop a regenerable, low-cost, high-efficiency pollution control technology for removal of gaseous pollutants from contaminated air streams. This innovative air filter technology will combine our novel proprietary Microlith® support elements with sorbent nanomaterials that can be tailored to capture a variety of targeted gaseous pollutants. Originall ...

    SBIR Phase I 2014 Environmental Protection Agency
  4. Green Materials for Doubling the Life of Drinking Water Pipeline

    SBC: HJ3 Composite Technologies, LLC            Topic: B

    Of the18,000 miles of pre-stressed concrete cylinder pipe (PCCP) within the drinking water transmission infrastructure laid between 1945 and 1996 in the United States, almost one-half, or 8,600 miles of pipe, is considered to be end-of-life infrastructure, awaiting funding for replacement. The American Society of Civil Engineers (ASCE) gave the United States a grade of D for its drinking water inf ...

    SBIR Phase I 2014 Environmental Protection Agency
  5. Targeted Inactivation of the CCR5 HIV Coreceptor with Peptide Nucleic Acids

    SBC: L2 Diagnostics, LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): Over 34 million people are currently living with HIV/AIDS. Combination antiviral therapies have significantly reduced the morbidity and mortality of the disease; however, there is currently no cure for the disease. Discovery that a naturally occurring variant of CCR5, the delta32 mutation, renders cells resistant to HIV infection has led to efforts by several a ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Formulation of LbL microparticle vaccine in microneedle array for intradermal del

    SBC: ARTIFICIAL CELL TECHNOLOGIES INC            Topic: NIAID

    Abstract The ability of the immune system to recognize and initiate an immune response to foreign particles such as bacteria and viruses has generated interest in development of particulate vaccine technologies. We are developing an innovative approach toproduce particulate vaccines via layer-by-layer (LbL) fabrication of synthetic microparticles (MP). We have shown that LbL-MP loaded with epitope ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Immune-based brain cancer diagnostic for rapid, accurate disease classification

    SBC: HealthTell Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): Accurate, early disease diagnosis and monitoring are critical aspects to effective prevention, treatment, and remission of disease. Most diagnostic methods available today are not simple or sensitive enough to significantly impact patients' response to treatment or survival outcome. This unmet need is highlighted by diseases, such as brain cancers, that o ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Practical high resolution microscopy of un-cut, un-embedded lung biopsies

    SBC: Applikate Technologies LLC            Topic: NCI

    DESCRIPTION (provided by applicant): This aim of this Phase I SBIR proposal from Applikate Technology, LLC, is to validate the use of ClearView, a novel approach to performing complete and non-destructive imaging of tissue specimens, for primary pathologyof lung biopsies. Error rates for diagnoses of lung cancer from biopsies may run as high as 15%. Although the root causes of errors are diverse, ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Peptide-Derived Orally-Active Kappa-Opioid Receptor Agonists for Peripheral Pain

    SBC: HALIMED PHARMACEUTICALS, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): Treatment of peripheral pain of various origins remains a major unmet medical need, affecting tens to hundreds of millions of people nationwide at some time during their lives. Kappa-opioid agonists have been shown in peripheral pain models to be particularly efficacious but suffer from centrally mediated effects that have limited their development. Perhaps the ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Engineered Neurotensin Fragments Targeting Neuropathic Pain

    SBC: JT Pharmaceuticals, Inc.            Topic: NIDCR

    DESCRIPTION (provided by applicant): Neuropathic pain management is a major unmet clinical need. Classically used medications, including opioids and non-opioids (primarily NSAIDs), have major side effects associated with their use, and many individuals donot respond to any medications. Neuropathic pain drugs with novel mechanisms of action are being sought as an alternative; however, the only succ ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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