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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Spectroscopic presciption verification system

    SBC: CENTICE CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Prescription dispensing errors at a pharmacy are a problem on a national level, at a rate of about 4 errors per day in a pharmacy filling 250 prescriptions daily. This translates to a gigantic amount of 51 million prescription errors per year with about 3 billion prescriptions being filled. There are as many as 7,000 deaths reported annually in the United State ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  2. Cell therapy of diabetes using broad spectrum multipotent stem cells

    SBC: PLUREON CORP.            Topic: N/A

    DESCRIPTION (provided by applicant): Transplantation of insulin-producing cells in many diabetes patients potentially would restore normal glucose homeostasis and prevent the severe long-term complications of the disease. However, the scarcity of donated pancreata currently limits transplantation of the whole organ or of isolated pancreatic islets to a tiny fraction of those patients who might ben ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Cell therapy of diabetes using broad spectrum multipotent stem cells

    SBC: PLUREON CORP.            Topic: N/A

    DESCRIPTION (provided by applicant): Transplantation of insulin-producing cells in many diabetes patients potentially would restore normal glucose homeostasis and prevent the severe long-term complications of the disease. However, the scarcity of donated pancreata currently limits transplantation of the whole organ or of isolated pancreatic islets to a tiny fraction of those patients who might ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  4. Antivirals Targeting Flavivirus Envelope Proteins

    SBC: L2 DIAGNOSTICS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop therapeutic antivirals to treat life-threatening flavivirus infections. Enfuvirtide, a clinically successful peptide HIV fusion inhibitor, is the prototype for a new class of antivirals that inhibit viral envelope protein structural rearrangements essential for viral entry into host cells. In preliminary experiment ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Antivirals Targeting Flavivirus Envelope Proteins

    SBC: L2 DIAGNOSTICS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop therapeutic antivirals to treat life-threatening flavivirus infections. Enfuvirtide, a clinically successful peptide HIV fusion inhibitor, is the prototype for a new class of antivirals that inhibit viral envelope protein structural rearrangements essential for viral entry into host cells. In preliminary experiment ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Development of an Autism Spectrum Disorder Screening Test based upon Metabolic Profiling of Fresh Blood Samples

    SBC: CIRCA BIOSCIENCE LLC            Topic: 102

    Autism spectrum disorderASDis a neurodevelopmental disorder characterized by significant deficits in reciprocal social interactionsimpaired communication and restrictedrepetitive behaviorswith a prevalence ofinchildren in the USEarly intervention programs have been shown to be effective for improving IQlanguageand social skills for toddlers as young asmonths of ageDiagnosis of ASD is currently bas ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. A Novel Treatment in a Bioterrorism Model of Pneumonic Plague Targets A1 ARs

    SBC: ENDACEA, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Yersinia pestis (Y. pestis), the causative agent of plague, is a Gram-negative bacillus that is classified as a Category A pathogen by the Centers for Disease Control and a logical choice as a biological weapon. It has the potential to generate mass casualties and initiate a global epidemic of pneumonic plague. A major virulence factor for Y. pestis is endotoxi ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Novel treatment of posttraumatic stress disorder

    SBC: ANAGIN            Topic: 101

    DESCRIPTION provided by applicant The present application andquot Novel Treatment for Posttraumatic Stress Disorderandquot addresses the critical need for efficacious treatments for posttraumatic stress disorder PTSD A key neural signaling cascade activated by a trauma experience is initiated by the excitatory neurotransmitter glutamate Activation of the NMDA receptor a glutamate receptor ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Nucleobase aminosugars with reduced ototoxicity

    SBC: NUBAD LLC            Topic: Y

    PROJECT SUMMARYAminoglycosides are one of the cheapest and well known antibiotics in clinical use for overyearsbut one of the major limitations in their use is their ototoxicityWe are developing fast and low cost methods to develop aminoglycosides with antiribosomal activities and reduced toxicityIn this projectwe will identify novel aminoglycoside antibacterialsthat show reduced ototoxicityComple ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Metal ion-functionalized soluble nanopolymers: A new analytical platform for plas

    SBC: TYMORA ANALYTICAL OPERATIONS LLC            Topic: 300

    DESCRIPTION provided by applicant Mass spectrometry based proteomics is an emerging technology that has seen possible applications everywhere The technique can potentially use one drop of our blood to reveal onset and progress of diseases Current Randamp D using plasma serum proteome sample sets however is severely limited by the high complexity and dynamic range of protein concentrations ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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