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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Optimization of a Therapeutic HIVSIV Multi-Antigen DNA Vaccine
SBC: PROFECTUS BIOSCIENCES, INC. Topic: NIAIDDESCRIPTION: The HIV pandemic is one of the greatest public health challenges in history. It is estimated that 33 million people are living with HIV and 2.7 million of those are newly infected In a number of developed countries, the risk of death associated with HIV-1 infection has sharply declined due to the use of highly active antiretroviral therapy (HAART). Unfortunately, the rate of new HIV i ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
An HIV Vaccine Strategy Based on Priming with rVSV Expressing FLSC
SBC: PROFECTUS BIOSCIENCES, INC. Topic: RDESCRIPTION Based on the prevailing evidence we believe that a highly effective vaccine for HIV prophylaxis must induce long lasting broadly cross reactive antibody responses to envelope that exhibit antiviral activity as well as multi antigen polyfunctional CD and CD T cell responses that produce antiviral chemokines and cytokines and are possibly biased towards an effector memory phenot ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Novel microarrays for DNA genotyping in the presence of excess background DNA
SBC: SCANOGEN INC. Topic: 172DESCRIPTION provided by applicant DNA microarrays are a primary tool for DNA genotyping because of their capacity to detect multiple targets simultaneously However DNA microarrays require fluorescent labeling and long incubation steps which limit their applicability Furthermore DNA microarrays are not capable of detecting DNA targets in the presence of excess background DNA This capacity ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Cerberus-LNR: A Tethered Lightfield 3D Endoscope for Advanced Minimally Invasive
SBC: XIGEN, LLC Topic: NIDDKDESCRIPTION (provided by applicant): The primary objective of this SBIR is to develop and pre-clinically evaluate a novel lightfield 3D endoscope, dubbed Cerberus-LNR, specially designed for laparoendoscopic single-site surgery (LESS), natural orifice translumenal endoscopic surgery (NOTES), and robotic LESS (R-LESS) (hereafter LNR) procedures. The miniature Cerberus-LNR lightfield 3D endoscope co ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Novel treatment of posttraumatic stress disorder
SBC: ANAGIN Topic: 101DESCRIPTION provided by applicant The present application andquot Novel Treatment for Posttraumatic Stress Disorderandquot addresses the critical need for efficacious treatments for posttraumatic stress disorder PTSD A key neural signaling cascade activated by a trauma experience is initiated by the excitatory neurotransmitter glutamate Activation of the NMDA receptor a glutamate receptor ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Laser Speckle Imaging Chip for Telehealth Applications
SBC: VASOPTIC MEDICAL, INC. Topic: NIADESCRIPTION provided by applicant There is a strong unmet need for a low cost and convenient technology that can assist researchers and healthcare personnel in gathering vascular data Such vascular imaging technology could assist in the short term clinica research on the diagnostics disease progression and effect of treatment prevention strategies ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Metal ion-functionalized soluble nanopolymers: A new analytical platform for plas
SBC: TYMORA ANALYTICAL OPERATIONS LLC Topic: 300DESCRIPTION provided by applicant Mass spectrometry based proteomics is an emerging technology that has seen possible applications everywhere The technique can potentially use one drop of our blood to reveal onset and progress of diseases Current Randamp D using plasma serum proteome sample sets however is severely limited by the high complexity and dynamic range of protein concentrations ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Nitric Oxide Microfluidic Sensor
SBC: CLINICAL SENSORS, INC. Topic: NIAIDDESCRIPTION provided by applicant This Small Business Innovation Research SBIR Phase I project aims to develop a microfluidic based nitric oxide NO sensor as an early sepsis risk assessment device Sepsis causes significant strain on the U S healthcare system consuming over $ billion annually due to extended hospital stays and significant morbidity and mortality Rapid diagnosis and in ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
RNA Detection as an Improved Diagnostic Assay for Human Leptospirosis
SBC: L2 DIAGNOSTICS LLC Topic: NIAIDDESCRIPTION provided by applicant Leptospirosis a zoonotic disease is an important public health problem worldwide It is caused by spirochete bacteria belonging to nine species and more than serovars of the genus Leptospira In the US there is increasing awareness of the importance of leptospirosis as the cause of disease among inner city populations military personnel and individuals ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
XRpro Radioactive Cesium Decorporation Agents
SBC: Icagen, Inc. Topic: NIAIDDESCRIPTION provided by applicant Caldera aims to develop an inexpensive stable selective decorporation decorp agent for cesium Cs Cs is easily obtainable by terrorists and treatments for exposures are Project Bioshield priorities for use in radiation nuclear emergencies high priority for DHHS NIH NIAID DAIT and a critical need for the Strategic National Stockpile S ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health