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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Developmentally Appropriate Technology for Science Assessment in Early Elementary Grades

    SBC: 3-C Institute for Social Development, Inc.            Topic: 99190018R0006

    In this project, researchers will develop a prototype of Science Quest, a tool to assess the science skills and understanding for students in grades 1 to 3. The prototype will deliver psychometrically validated assessment items in a game-like format. Educators will be able to assign and monitor completion of science assessments, view assessment results in real-time with reports at the individual a ...

    SBIR Phase I 2018 Department of EducationInstitute of Education Sciences
  2. Topic 377: Enabling Clinical Decision Support for Guideline Based Cancer Symptom Management

    SBC: KLESIS, LLC            Topic: NCI

    The objective of this proposal is to develop an electronic, rule-based clinical decision support system (CDS-Sx) that leverages national clinical practice guidelines (CPGs) to improve cancer symptom management. Specific tasks that will be performed include: 1) create software-ready computable algorithms for managing cancer-related fatigue and constipation that have been vetted with diverse cancer ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Topic 375: 18F PET Tracer For Imaging PD-L1 (Moonshot)

    SBC: SIBTECH, INC.            Topic: NCI

    New therapies, designed to enhance anti-tumor immunity are based on the blockade of the checkpoint components, either PD-1 on immune cells or PD-L1 on tumor cells. This strategy, while being spectacularly successful in some patients for some cancers, fails for many other patients. The expression of PD-L1 is highly dynamic and its prevalence within tumors can vary significantly over time. The curre ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Topic 374: Targeted and Sustained Release Microparticles for Colon Cancer Chemoprevention

    SBC: ZYMERON CORP            Topic: NCI

    Colorectal Cancer (CRC) is the third most common cancer both in men and women, as well as the second leading cause of cancer deaths with an estimated 135,430 new cases diagnosed and 50,260 deaths for 2017 in the United States. Given the limitations of screening tests and poor prognosis associated with advanced stage colorectal cancer, it would be of great interest in exploring chemoprevention stra ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Rapid Baseline Free Organophosphate Exposure Diagnostic Test

    SBC: Countervail Corporation            Topic: 105

    AbstractThe prolific worldwide misuse of organophosphateOPpesticidescoupled with a grave homeland security concern that OP based nerve agents may be deployed either against our troops or civilians on our home soilhas stimulated the search for rapidminiaturized and inexpensive point of carePOCdiagnostic devices for first responders and medical personnel to detect the degree of OP exposureIdentifica ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Designer Proline-rich antimicrobial peptide Chaperone protein inhibitor (DPC) for treating multi-drug resistant wound infections

    SBC: Arrevus, Inc.            Topic: NIAID

    Project SummaryOver $billion is spent annually in the US treating chronicnon healing woundsmany of which face lifethreatening complications due to infectionsWound infections are difficult to treat due to the frequency of antibiotic resistance as well as the formation of biofilmsa community of bacteria covered by an extracellular polymeric substanceBiofilm related infections can result in a substan ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Innovative TME-specific Pro-CAR T-cells for Immunotherapy of Solid Tumors

    SBC: Panacise Bio, Inc.            Topic: 102

    Abstract This project seeks to develop the next generation pro CARs that are inactive in normal tissues but selectively activated in the tumor microenvironmentTMEThe project is based on our previous development of a novel class of chimeric antigen receptors on the basis of single domain antibody mimics that recognize ErbB family membersSDAErbBon the surface of cancer cellsWe propose two specific a ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. An antigen-detection assay to diagnose Babesia microti infection

    SBC: L2 DIAGNOSTICS LLC            Topic: NIAID

    Project Summary Human babesiosis is a malaria like multisystem disease caused primarily by Babesia microtian emerging apicomplexan parasite that infects and develops within human erythrocytesThe parasite is transmitted to humans by the tick vector Ixodes scapularis and can also be introduced through blood transfusionInfection can cause flu like symptomsand severe infection can be fatalin particula ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Improving Anticoagulation Monitoring in Pediatric Patients: Use of a Microfluidic Platform to Test Low Volume Blood Samples Obtained by Heel-Stick Collection

    SBC: BAEBIES, INC.            Topic: NHLBI

    ABSTRACT Improving Anticoagulation Monitoring in Pediatric PatientsUse of a Microfluidic Platform to Test Low VolumeBlood Samples Obtained by Heel Stick CollectionFast Track SBIRThe goal of this Fast Track SBIR project is to develop a near patient platform for laboratory monitoring of anticoagulantsheparinheparinoidsand oral direct Factor Xa inhibitorsin children utilizing blood obtained from heel ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Aptamer Beacons For High-Throughput Assay Development

    SBC: Epicypher, Inc.            Topic: 300

    PROJECT SUMMARYEnzymes that addwritersor removeerasershistone post translational modificationsPTMsare high value drug targets with the potential to treat diverse human pathologiese gcancerneurodegeneration or inflammationModified histone peptides are widely used as in vitro substrates due to their short development cycle and low costHowevernucleosomesNucsrepresent the physiological substrate for c ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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