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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. AAV2-ASPA-Based Metabolic Intervention for Alzheimer's Disease

    SBC: ASKLEPIOS BIOPHARMACEUTICAL, INC.            Topic: NIA

    Abstract We propose to initiate preclinical development of a gene therapeutic targeted to Alzheimer's Disease. The World Health Organization's and Alzheimer's Disease International's report on Dementia (2012) recognizes that the global burden of AlzheimerDisease is forecast to worsen significantly with prevalence predicted to double every 20 years. Interventions that could prov ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. A biomarker of aging as a predictor of kidney transplant function

    SBC: HEALTHSPAN DIAGNOSTICS, LLC            Topic: NIA

    ABSTRACT The number of kidney transplant candidates on the waiting list continues to increase each year, while the number of kidney donations remains stagnant. The enduring donor shortage compels clinicians to use kidneys from marginal donors, referred toas expanded criteria donors (ECD). ECD kidneys, obtained primarily from older donors, have a higher risk of delayed graft function and graft loss ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. A Data-driven Approach to Improve Nursing Workflow and Patient-centered Care

    SBC: Transcendent International, LLC            Topic: NIMHD

    DESCRIPTION (provided by applicant): Patient-centered care recognizes patients' desires, opinions, and preferences as equal in importance to those of healthcare professionals, and emphasizes the need to educate and empower patients to play an active role in their care. The achievement of patient-centered care is associated with increased patient and provider satisfaction, improved health outc ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Affinity Capture Peptides for Clinical Mass Spectrometric Assays in Plasma

    SBC: AFFINERGY, LLC            Topic: NIGMS

    DESCRIPTION (provided by applicant): We will develop the first assay for multiplexed combinations of all 14 Bone Morphogenetic Proteins. Immunoassays are the gold standard for measuring proteins in clinical samples. However these antibody- based tests neither quantitate protein analyte variants, nor multiplex across large numbers of superfamily members. In addition, the availability of polyclona ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. A Generic Cross-Platform Perception API for Unmanned Vehicles

    SBC: Honeybee Robotics, Ltd.            Topic: OSD13HS4

    ABSTRACT: Autonomous vehicles lack a standardized mechanism for seamless cross-platform sharing of testing frameworks and evaluations of basic tasks. The ability to execute common tests on various hardware platforms is essential in order to be able to e

    SBIR Phase I 2014 Department of DefenseDefense Threat Reduction Agency
  6. A microRNA based prognostic service that predicts melanoma metastasis likelihood

    SBC: RGENIX, INC.            Topic: NCI

    ABSTRACT Melanoma is a highly prevalent cancer that kills patients by metastasizing and destroying distal organs. To date, there are no effective molecular prognostic services available for stratifying patients that are at high risk for metastatic relapsein the adjuvant setting. By stratifying patients into high-risk versus low-risk, therapies could be tailored to those patients that stand to bene ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. A Millimeter-wave Tunable Cavity for Ultra-sensitive Solids and Liquids DNP-NMR at Low Budget

    SBC: DOTY SCIENTIFIC, INC.            Topic: NIA

    ? DESCRIPTION (provided by applicant): NMR is probably the most powerful and widely used analytical technique for structure determination and function elucidation of molecules of all types, but it suffers from low sensitivity, particularly for insoluble biological macromolecules. Dynamic Nuclear Polarization (DNP) with Magic Angle Spinning (MAS) has recently demonstrated S/N gains exceeding t ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. An Intervention to Improve Cervical Cancer Detection among High Risk Latinas

    SBC: QURVE LEARNING LLC            Topic: NIMHD

    Project Summary/Abstract Latinas have 70% higher incidence and double the mortality rate of cervical cancer than non-Latinas in the U.S., primarily due to low rates of screening and COLPOscopy, the recommended follow-up for abnormal Papanicolou (Pap) tests. Factors related to low rates include access to health care, anxiety, fear of pain and cancer, low educational and low health literacy levels. ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. A Novel Recombinant Protein for Mitigating Total Body Radiation Injury

    SBC: THERASOURCE, LLC            Topic: NIAID

    DESCRIPTION provided by applicant This SBIR Phase I proposal is intended to demonstrate the feasibility of developing a novel and effective therapeutic agent for acute radiation injury The threat of nuclear terrorism remains high and there is a possibility of a nuclear power plant leak both of which can cause acute radiation injury at a large scale Currently there are no therapeutic agents ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. A Novel Small Molecule Therapeutic for Alcoholic Chronic Pancreatitis

    SBC: Angion Biomedica Corp.            Topic: NIAAA

    DESCRIPTION (provided by applicant): Chronic Pancreatitis (CP) is characterized by continuous or recurrent inflammation of the pancreas that leads to permanent destruction of the pancreas resulting in exocrine and endocrine insufficiency. CP is a common disorder associated with significant morbidity and mortality with an incidence of 8.2 and a prevalence of 27.4 per 100 000 population. The etiolog ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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