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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. AAV2-ASPA-Based Metabolic Intervention for Alzheimer's Disease

    SBC: ASKLEPIOS BIOPHARMACEUTICAL, INC.            Topic: NIA

    Abstract We propose to initiate preclinical development of a gene therapeutic targeted to Alzheimer's Disease. The World Health Organization's and Alzheimer's Disease International's report on Dementia (2012) recognizes that the global burden of AlzheimerDisease is forecast to worsen significantly with prevalence predicted to double every 20 years. Interventions that could prov ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. A biomarker of aging as a predictor of kidney transplant function

    SBC: HEALTHSPAN DIAGNOSTICS, LLC            Topic: NIA

    ABSTRACT The number of kidney transplant candidates on the waiting list continues to increase each year, while the number of kidney donations remains stagnant. The enduring donor shortage compels clinicians to use kidneys from marginal donors, referred toas expanded criteria donors (ECD). ECD kidneys, obtained primarily from older donors, have a higher risk of delayed graft function and graft loss ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. A Data-driven Approach to Improve Nursing Workflow and Patient-centered Care

    SBC: Transcendent International, LLC            Topic: NIMHD

    DESCRIPTION (provided by applicant): Patient-centered care recognizes patients' desires, opinions, and preferences as equal in importance to those of healthcare professionals, and emphasizes the need to educate and empower patients to play an active role in their care. The achievement of patient-centered care is associated with increased patient and provider satisfaction, improved health outc ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. A diagnostic for maternal autoAb to Caspr to predict increased risk of autism spectrum disorder in children

    SBC: Spark2Flame, Inc            Topic: NICHD

    PROJECT SUMMARY Autism Spectrum Disorder ASD describes a collection of neurodevelopmental abnormalities of varying severity that have been estimated to impact more than of Americans mostly males ASD can negatively impact one s ability to communicate and navigate social interactions In its most severe forms ASD also can lead to self destructive repetitive behaviors that require affli ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. A D osteoarthritis model targeting patient populations with high risk genetic polymorphisms

    SBC: Cytex Therapeutics, Inc.            Topic: NIAMS

    Abstract Osteoarthritis OA is a degenerative joint disease that affects an estimated million adults in the United States and results in an economic burden of over $ billion per year Although the burden of OA is immense current non surgical treatments are only palliative and no disease modifying OA drugs DMOADs presently exist to address the problem This lack of success in identifying ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Advanced virtual simulator for real time ultrasound guided renal biopsy training

    SBC: Kitware, Inc.            Topic: 400

    ABSTRACT The objectives of the Kidney Precision Medicine Project KPMP project are to create a kidney tissue atlas define disease subgroups and identify critical cells pathways and targets for novel therapies by obtaining and evaluating kidney biopsies from participants with acute kidney injury AKI and chronic kidney disease CKD As part of this effort there is a need for new technologie ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Advancing Technology to Prevent School Violence

    SBC: Happy People Games, LLC            Topic: edIES17R0005

    With this Phase I funding, the project team will develop and test a prototype of a game-based application, Keeping It Real, to promote healthy relationships and prevent sexual misconduct among high school students. The prototype will include a game-based storytelling structure with branching narrative where students' choices determine how the story unfolds, a component to promote individual and gr ...

    SBIR Phase I 2017 Department of EducationInstitute of Education Sciences
  8. Affinity Capture Peptides for Clinical Mass Spectrometric Assays in Plasma

    SBC: AFFINERGY, LLC            Topic: NIGMS

    DESCRIPTION (provided by applicant): We will develop the first assay for multiplexed combinations of all 14 Bone Morphogenetic Proteins. Immunoassays are the gold standard for measuring proteins in clinical samples. However these antibody- based tests neither quantitate protein analyte variants, nor multiplex across large numbers of superfamily members. In addition, the availability of polyclona ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. A Generic Cross-Platform Perception API for Unmanned Vehicles

    SBC: Honeybee Robotics, Ltd.            Topic: OSD13HS4

    ABSTRACT: Autonomous vehicles lack a standardized mechanism for seamless cross-platform sharing of testing frameworks and evaluations of basic tasks. The ability to execute common tests on various hardware platforms is essential in order to be able to e

    SBIR Phase I 2014 Department of DefenseDefense Threat Reduction Agency
  10. A Graphene Nanoparticle Based X ray Computed Tomography Contrast Agent ForSubjects At Risk for Contrast Induced Nephropathy

    SBC: Theragnostic Technologies Inc.            Topic: 300

    Abstract This SBIR phase proposal is to demonstrate the pre clinical safety and efficacy of a novel carbon nanostructure based X ray computer tomography CT contrast agent CA for imaging and monitoring in patients with renal failure or at risk of contrast induced nephropathy CIN Routine contrast enhanced CT scans relays crucial information about diseases and injuries thus aiding the clini ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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