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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Aptamer-Based Detection of Cardiac Biomarker Glycosylation States Using APT-SNAP

    SBC: Proteovista LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Aptamer Based Detection of Cardiac Biomarker Glycosylation States Using APT SNAP Arrays PIs Christopher L Warren and Mary S Ozers The presence of cardiac related biomarkers in patient biospecimens can provide important insight into diagnosis of cardiovascular disease its progression and optimal therapies for treatment Most of the cardiac biomarkers in cli ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a novel highly effective influenza vaccine

    SBC: Flugen, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Seasonal influenza flu virus an NIAID category C priority pathogen causes widespread infection resulting in at least million cases of severe illness and deaths worldwide Young children and elderly or immunocompromised individuals are typically at greater risk of severe illness or death from influenza Newly emerging strains can result ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Development of Peptide Antibiotic Nucleic Acids

    SBC: NUBAD, LLC            Topic: NIAID

    DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. A Novel Substrate to Amplify Growth Factor Impact on hPSC Differentiation

    SBC: PRIMORIGEN BIOSCIENCES INC.            Topic: 300

    DESCRIPTION provided by applicant Primorigen Biosciences R Project Abstract Primorigen will use SBIR funds to develop a paradigm changing technology for expansion and directed differentiation of human pluripotent stem cells hPSCs using a novel peptide that dramatically reduces costs by amplifying the impact of endogenous growth factors and minimizing the need for exogenous growth factors Th ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. MASS PRODUCTION OF PERSONALIZED HUMAN ENGINEERED HEART TISSUES

    SBC: Invivosciences, Inc.            Topic: 200

    DESCRIPTION provided by applicant Cardiomyopathy has various forms including hypertrophic cardiomyopathy HCM in prevalence could cause sudden cardiac death in athletes Dilated Cardiomyopathy DCM in prevalence results in an enlarge left ventricle Arrhythmogenic Right Ventricular Dysplasia Cardiomyopathy ARVD C in prevalence causes cardiac fibrosis Yearly over $ ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. STTR Phase I: Ferrofluidic enclosures for enhanced control of thermal and magnetic fields in spin-stabilized atomic micro-devices

    SBC: COMMET LLC            Topic: EW

    The broader impact/commercial potential of this project is determined by new consumer products and new industries which would flourish on portable and reliable atomic clocks, gyroscopes, and magnetometers when they become available. Proposed compact thermal and magnetic enclosure reduces the most bulky part of such devices and provides an avenue for further miniaturization. A chip-scale atomic clo ...

    STTR Phase I 2014 National Science Foundation
  7. SBIR Phase I: New approach for producing increased quantities of human antibodies for research, medical, and biodefense applications

    SBC: ALPHA UNIVERSE LLC            Topic: BT

    The broader impact /commercial potential of this Small Business Innovation Research (SBIR) project will address the needs of the antibody market for fast and inexpensive production of antibodies. Antibodies are among the most utilized molecular tools in the life sciences, whose applications span a variety of areas in biological science and medicine. The worldwide antibody market was estimated at a ...

    SBIR Phase I 2014 National Science Foundation
  8. SBIR Phase I: Cloud-based Simulation Service for Makers

    SBC: INTACT SOLUTIONS INC.            Topic: MN

    The broader impact/commercial potential of this project is in making structural simulation widely available to communities of makers, small businesses, and manufacturing enterprises, leading to dramatic improvements in performance, quality, manufacturability, and cost savings. If successful, the proposed research will result in a cloud-based simulation service, a disruptive technology holding the ...

    SBIR Phase I 2014 National Science Foundation
  9. SBIR Phase IB: Nanomanufactured optical elements for fiber optic connectors

    SBC: MagAssemble, LLC            Topic: MN

    The broader impact/commercial potential of this project is in the field of advanced manufacturing. This project develops a low cost, high resolution nanomanufacturing technology platform for building optical fiber devices with approaches that are currently out of reach because of manufacturing cost. While both size and cost reductions are needed for this technology to address the optical component ...

    SBIR Phase I 2014 National Science Foundation
  10. SBIR Phase I: Ambient-Pressure Plasma Degassing for Low Cost Vacuum Glass

    SBC: V-Glass, INC            Topic: CT

    The broader impact/commercial potential of this project will be to remove a barrier to commercialization of low-cost vacuum glass, a major building energy efficiency improvement. Universal use (unachievable but a useful point of reference) could reduce total U.S. energy use by 5% (about 4 quadrillion BTU/year), more than $15 billion/year at today?s natural gas prices, while adding minimal cost to ...

    SBIR Phase I 2014 National Science Foundation
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