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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Polo box PLK Inhibitors Target Tumors Resistant to ATP Competitive Compounds
SBC: PPI PHARMACEUTICALS, LLC Topic: NCIPolo like kinase PLK is a central player in regulating entry into and progression through mitosis Many studies have validated PLK as an anti tumor drug target and its inhibition is potently anti proliferative to cancer cells However recent data suggests that there are two major disadvantages of the conventional approach to blocking the kinase activity of PLK First both general kinome ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
A Novel Scaffold to Promote Skin Regeneration
SBC: FirstString Research, Inc Topic: NIAMSPROJECT SUMMARY Dermal scarring affects more than million people worldwide annually over million people are injured in motor vehicle accidents over million patients are severely burned and thousands of warriors are wounded in military blasts In severe burns more than of patients develop hypertrophic scar contraction which leads to hypertrophic scar contractures HSc HSc a ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
A Novel Millimeter wave mmw DNP EPR Front end Compatible with Versatile High field NMR Probes
SBC: DOTY SCIENTIFIC, INC. Topic: NIAA Novel Millimeter wave mmw DNP EPR Front end Compatible with Versatile High field NMR Probes Abstract There has been explosive growth in interest in Dynamic Nuclear Polarization DNP with Magic Angle Spinning MAS over the past five years because it has demonstrated S N gains exceeding two orders of magnitude at K compared to conventional MAS NMR and non spinning NMR of biological macro ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Ice Free Vitrification and nanowarming of large cartilage samples for transplantation
SBC: TISSUE TESTING TECHNOLOGIES LLC Topic: NIAMSResurfacing of articular cartilage with cold stored osteochondral allografts is employed clinically for repair of trauma and osteoarthritis induced articular cartilage surface damage Chondrocyte viability of transplanted articular cartilage is accepted as one of the determinants of outcome following osteochondral allograft transplantation We have previously developed an ice free vitrification me ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Low Cost Handheld Tactile Imaging Device for Breast Cancer Screening
SBC: VAJRA INSTRUMENTS, INC. Topic: 102Palpation has been routinely used by physicians to diagnose diseases for centuries In Clinical Breast Examination CBE medical personnel screen for suspect lesions that are to fold stiffer than surrounding tissue by palpation using two or three fingers followed by precession about a fixed in contact area Typical pressure to avoid discomfort and also feel deeper palpable objects r ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
MUC assay for the early diagnosis and management of benign and malignant pancreatic diseases
SBC: Sanguine Diagnostics And Therapeutics, Inc. Topic: 300Abstract The goal of this Fast track application is to develop a non invasive diagnostic test based on MUC and MUC mucins that can serve as an adjunct to cytological analysis of fine needle aspirates FNAs for accurate prediction of malignancy in patients with cystic pancreatic lesions Due to asymptomatic nature and lack of methods for early detection andgt of pancreatic cancer PC p ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
SBIR Phase I Protein A membrane columns for rapid protein purification
SBC: Purilogics, LLC Topic: 400Project Summary This SBIR Phase I project is significant because it addresses a critical need for products that increase research productivity during drug discovery and development Improving research productivity plays a key role in translating biologics from research labs to approved medications efficiently and economically Product purification often limits the productivity and time delays in ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Evaluation of a Connexin based Peptide for the Treatment of Age Related Macular Degeneration
SBC: FirstString Research, Inc Topic: NPROJECT SUMMARY ABSTRACT FirstString Research has identified a novel peptide that shows therapeutic potential in the treatment of age related macular degeneration AMD This Phase I SBIR will assess both the feasibility and mechanism of action involved in the topical delivery of a synthetic connexin based peptide aCT for the treatment of AMD AMD is a retinal disease in patients who progress ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
AN ORGANOID AVATAR BIOBANK FOR CANCER DISPARITIES
SBC: Delphi Genomics, LLC Topic: NCIThis project seeks to establish a colorectal cancer organoid avatar bio bank from an ethnically and genetically diverse patient population that is approximately African American We will make use of discarded de identified surgical specimens to establish dimensional cultures of tumor and matched normal colon stem cells organoids Organoid avatars will be characterized by WNT EGF and ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Peptide-Derived Orally-Active Kappa-Opioid Receptor Agonists for Peripheral Pain
SBC: HALIMED PHARMACEUTICALS, INC. Topic: NIDADESCRIPTION (provided by applicant): Treatment of peripheral pain of various origins remains a major unmet medical need, affecting tens to hundreds of millions of people nationwide at some time during their lives. Kappa-opioid agonists have been shown in peripheral pain models to be particularly efficacious but suffer from centrally mediated effects that have limited their development. Perhaps the ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health