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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Development of an Autism Spectrum Disorder Screening Test based upon Metabolic Profiling of Fresh Blood Samples
SBC: CIRCA BIOSCIENCE LLC Topic: 102Autism spectrum disorderASDis a neurodevelopmental disorder characterized by significant deficits in reciprocal social interactionsimpaired communication and restrictedrepetitive behaviorswith a prevalence ofinchildren in the USEarly intervention programs have been shown to be effective for improving IQlanguageand social skills for toddlers as young asmonths of ageDiagnosis of ASD is currently bas ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Nucleobase aminosugars with reduced ototoxicity
SBC: NUBAD LLC Topic: YPROJECT SUMMARYAminoglycosides are one of the cheapest and well known antibiotics in clinical use for overyearsbut one of the major limitations in their use is their ototoxicityWe are developing fast and low cost methods to develop aminoglycosides with antiribosomal activities and reduced toxicityIn this projectwe will identify novel aminoglycoside antibacterialsthat show reduced ototoxicityComple ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Point of care assay for serodiagnosis of Leptospirosis
SBC: IMMUNO TECHNOLOGIES INC Topic: NIAIDLeptospirosis is the most widespread neglected zoonotic disease in the worldIt affects vulnerable populations such as rural subsistence farmers and urban slum dwellersUrban epidemics are reported in cities in developing countries and will likely increase as the world s slum population doubles tobillion byAn unexpected outbreak was reported in New York City recently and climate change may account f ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Emodin as a complementary dietary therapy to reduce toxicity of 5 fluorouracil
SBC: AcePre, LLC Topic: NCCIHPROJECT SUMMARYfluorouracilFUhas been the first choice chemotherapy drug for colorectal cancerCRCfor many yearshoweverits clinical utility remains hindered by hematopoietic and gastrointestinal toxicities resulting from its non selectivitySide effects include fatigueloss of appetiteand diarrhea among othersall of which can lead to reduced quality of lifeThe economic burden associated with chemothe ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Development of a Novel Clinical Diagnostic Assay for Peripheral T-cell Lymphoma (PTCL)
SBC: HEALTHCHART LLC Topic: 102Project Summary Abstract Peripheral T cell lymphomaPTCLis a heterogeneous cancer that constitutes up toof all non Hodgkin lymphomaNHLThe World Health Organization classification recognizes a number of distinct subtypes of PTCL but the diagnosis of these different subtypes is challenging even for expert hematopathologistsFurthermoreof PTCL cases are not classifiable into any specific subtype at all ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A Molecular Diagnostic Assay for Accurately Differentiating Melanoma from Benign Lesions
SBC: Frontier Diagnostics, LLC Topic: 102AbstractMelanoma is the third most common form of skin cancer with estimatednew cases diagnosed in the United States in the yearCurrent routine diagnostic approaches utilize microscopic evaluation of thinly sectioned patient biopsiesbut in certain cases diagnosis can be contentious even among expertsThe overall goal of this multi phase SBIR project is to developvalidateand commercialize MelanoMapT ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Targeted Nanotherapy to Donor Organ Endothelia Modulates Early Immune Responses and Protects Against Late Graft Failure
SBC: ToleRaM NanoTech LLC Topic: NIBIBABSTRACT Transplantation is an accepted and highly successful therapy for end stage organ diseaseWhile success rates and survival have risen steadilydue largely to improved immunosuppression regimesthere is a growing appreciation that damage and inflammation that occur early in the life of the graftsignificantly impact chronic rejection and thus long term survivalCentral to these early event injur ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
DMSO-free Cryopreservation of Bone Marrow-derived Stem Cells
SBC: TISSUE TESTING TECHNOLOGIES LLC Topic: NHLBIABSTRACT Stem cell transplantation in the form of bone marrowperipheral blood or cord blood derived cells is commonly performed for reconstitution of the hematopoietic system of patients suffering from cancers and non malignant diseasesCurrent practice for cryopreservation of hematopoietic and mesenchymal stem cells is to employ the cell permeating cryoprotectant dimethylsulfoxideoften with an add ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Construction and testing of a rabbit cornea-equivalent for evaluation of chemical injury in vitro
SBC: TISSUE TESTING TECHNOLOGIES LLC Topic: NIEHSABSTRACTWe propose combination of the rabbit cornea endothelial and epithelial cells with bioengineered scaffolds in cell culture well insertsThis technology could significantly reduce the use of rabbits for the Draize rabbit eye irritation assayThe barrier to commercialization is the lack of an effective method for storingbankingof living bioengineered cornea equivalentsWe will combine cell expan ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Autoscreen: An innovative e-health solution for early identification of autism spectrum disorder
SBC: Adaptive Technology Consulting, LLC Topic: 103Project SummaryEarly accurate identification and treatment of young children with Autism Spectrum DisorderASDrepresents a pressing public health and clinical care challengeGiven mounting evidence that earlyaccurate diagnosis of ASD is possible and very young children who receive intervention can demonstrate substantial gains in functioningcurrent American Academy of Pediatrics practice guidelines ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health