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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A biodegradable ophthalmic drug delivery device

    SBC: Notus Laboratories, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Our long-term research goal is to develop an ophthalmic, nanofiber-based, biodegradable device that will provide extended release of therapeutic agents to the posterior segment of the eye via transscleral and intravitr eal approaches. This platform device will address the major technical problem in the treatment of posterior eye diseases (diabetic retinopathy, ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  2. Accurate Early Detection of Preeclampsia

    SBC: ARBOGAST PHARMACEUTICALS, INC.            Topic: N/A

    Use of a new noninvasive test for the accurate early detection of preeclampsia is proposed as a tool to screen women during early stages of pregnancy. Preeclampsia affects 10% of the 4 million pregnancies in the U.S. each year and is the leading cause of maternal and neonatal medical complications and death. There is currently no means of detecting preeclampsia prior to onset of clinical symptoms ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  3. A Cell-based Assay for Botulinum Neurotoxin Detection and Development

    SBC: Q-Track Corporation            Topic: NIEHS

    DESCRIPTION (provided by applicant): The proposed effort aims to dramatically enhance the realism of radiation safety training for Emergency Responders, both First Responders, as well as Skilled Support Personnel. The goal is to develop andevaluate realistic dosimetry simulation or Dosimulation tools. These Realistic, Accurate Dosimulation (RAD) tools will be the centerpiece for ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Acne Vaccines Targeting a Surface Sialidase and a Secreted CAMP Factor Toxin

    SBC: VAXIN INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Propionibacterium acnes (P. acnes) is most notably recognized for its role in acne vulgaris, the most common skin disease, affecting 85-100% of the population at some point in their lives. Current treatments for vulgari s acne using isotretinoin (13-cis-retinoic acid) or antibiotics can have many undesirable effects, including depression, teratogenicity, hormon ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  5. Active Interrogation for Nuclear Materials Detection

    SBC: PHYSITRON, INC.            Topic: DTRA05009

    Physitron proposes the development of a Thermal Neutron Beam Concentrator for use in detecting strategic nuclear material (SNM) such as U, Pu, Th, etc. A compact neutron generator developed by Lawrence Berkeley National Lab will provide 2.4 MeV neutrons that will be moderated, concentrated into a high flux beam, and propagated in air across distances up to three meters. Any SNM in the beam's path ...

    SBIR Phase I 2005 Department of DefenseDefense Threat Reduction Agency
  6. Active Material Technology to Improve Solar Sail Performance for Space Weather Monitoring

    SBC: NEXOLVE HOLDING CO LLC            Topic: 96

    Development of a reflection control and direction device (RCDD) is proposed. This innovative device will progress the state of the art for propulsion of solar sails used to fly space weather monitoring sensors to sub-LaGrange point orbits for earlier warning times of impending destructive space weather events. A reflection control device (RCD) utilizes polymer dispersed liquid crystal (PDLC) mater ...

    SBIR Phase I 2023 Department of CommerceNational Oceanic and Atmospheric Administration
  7. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Reliable diagnostic differentiation between acute and chronic myocardial infarcts would be of great benefit for cardiac surgeons and interventional cardiologists. Such differentiation could be used to make decisions about which vessels and in what order would be reopened or bypassed. MRI is an intrinsically noninvasive diagnostic tool and the Delayed Enhancemen ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  9. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Reliable diagnostic differentiation between acute and chronic myocardial infarcts would be of great benefit for cardiac surgeons and interventional cardiologists. Such differentiation could be used to make decisions about which vessels and in what order would be reopened or bypassed. MRI is an intrinsically noninvasive diagnostic tool and the Delayed Enhancemen ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  10. A Defined Biomatrix Model for Human Vascular Studies

    SBC: Diversified Scientific Inc            Topic: N/A

    DESCRIPTION (provided by applicant): In our initial application we successfully argued for the need to develop a novel human biomatrix model system to examine in vitro the neovascularization process in humans. The overall goal was and is to develop and commercialize the new human bioassay system employing defined Amgel matrices. This human biomatr ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
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