Award Data

There is growing interest in computerized systems to increase accessibility of assessments for students with disabilities. Technology offers an ideal platform for implementing Universal Design (UD) principles for assessment to better accommodate student diversity and support broad student participation. The goal of this SBIR project is to integrate Universal Design principles for assessment into t ...

DESCRIPTION (provided by applicant): The proposed effort aims to dramatically enhance the realism of radiation safety training for Emergency Responders, both First Responders, as well as Skilled Support Personnel. The goal is to develop andevaluate realistic dosimetry simulation or Dosimulation tools. These Realistic, Accurate Dosimulation (RAD) tools will be the centerpiece for ...

DESCRIPTION: An estimated 2.5 billion people, or about one-third of the world's population, rely on biomass fuel for cooking. Emissions from biomass cook stoves contribute to global climate change, indoor/local air quality issues, and related health effects. In particular, indoor ir quality issues related to biomass cook stoves contribute significantly to rates of acute respiratory infection ...

DESCRIPTION: Pulmonary drug delivery is increasingly used for both treatment of lung diseases (such as asthma and chronic obstructive pulmonary disease) and in delivering drugs to the systemic circulation. To reach the desired effectiveness and safety oforally/nasally inhaled drugs, appropriate deposition of drugs on targeted region is essential. Due to complex pharmaceutical and physiological fa ...

DESCRIPTION (provided by applicant): Type 2 diabetes (T2D) is a devastating disease that has undergone a striking increase in prevalence in the U.S. and worldwide. Although a number of different drugs exist to help manage this condition, unfortunately morethan 1/3 of affected individuals fail to achieve healthy blood glucose levels. Of the therapies used, metformin (i.e. Glucophage, a member of th ...

DESCRIPTION (provided by applicant): Training mentored youth and their caregivers to work together successfully with their mentor and mentoring program is critically important for achieving a safe, high-quality, sustained mentoring relationship, and for obtaining positive youth outcomes. Training for mentees and their caregivers is considered a best practice in the field of mentoring; however, man ...

DESCRIPTION (provided by applicant): Molecular interactions form the foundation of biology and chemistry. They are central to life itself and determine catalytic activity, cellular function, and therapeutic efficacy. The vast majority of diagnostic procedures depend on some type of specific molecular interaction. Therefore, the ability to perform pure liquid-phase molecular binding analysis at hi ...

Protein manufacturing is of paramount importance to chemical and biological defense applications. High-throughput protein purification is a critical need for rapidly scaling the target protein product. Existing purification methods primarly rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermea ...

DESCRIPTION (provided by applicant): Myelosuppression continues to represent the major dose-limiting toxicity of cancer chemotherapy, resulting in considerable morbidity and mortality along with frequent reductions in chemotherapy dose intensity, which maycompromise disease control and survival. G-Zero Therapeutics, with operations in the Research Triangle Park of North Carolina, has developed a n ...

Safe and efficient air ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these issues, we propose to develop and demonstrate a novel bioaerosol ionization and collection ...