Award Data

DESCRIPTION (provided by applicant): The incidence of congestive heart failure (CHF) is increasing worldwide with over one million new cases diagnosed annually. Over the past 30 years, counterpulsation with an intra-aortic balloon pump (IABP) has been widely and successfully used as a short-term treatment for cardiac dysfunction. However, counterpulsation is limited by its location within the desc ...

DESCRIPTION (provided by applicant): Reliable diagnostic differentiation between acute and chronic myocardial infarcts would be of great benefit for cardiac surgeons and interventional cardiologists. Such differentiation could be used to make decisions about which vessels and in what order would be reopened or bypassed. MRI is an intrinsically noninvasive diagnostic tool and the Delayed Enhancemen ...

DESCRIPTION (provided by applicant): Reliable diagnostic differentiation between acute and chronic myocardial infarcts would be of great benefit for cardiac surgeons and interventional cardiologists. Such differentiation could be used to make decisions about which vessels and in what order would be reopened or bypassed. MRI is an intrinsically noninvasive diagnostic tool and the Delayed Enhancemen ...

DESCRIPTION (provided by applicant): Adenovirus vectors are employed in a wide range of gene therapy and vaccine applications due to several attractive features such as high titers, structural stability, broad infectivity, established protocols for genetic manipulation and high levels of transgene expression with lack of host genome integration. However development of these vectors in the clinical ...

DESCRIPTION (provided by applicant): Adenovirus vectors are employed in a wide range of gene therapy and vaccine applications due to several attractive features such as high titer attainment, structural stability, broad infectivity, established protocols for genetic manipulation and high levels of transgene expression with lack of host genome integration. However development of these vectors in th ...

DESCRIPTION provided by applicant Pulmonary drug delivery has emerged as a noninvasive alternative route for the treatment of lung diseases asthma COPD CF and lung cancer In order to obtain the desired level of effectiveness and safety of the inhaled drugs an appropriate deposition on the targeted region and subsequent absorption in the targeted region is vital Multiscale multidisciplin ...

ABSTRACT Diabetes is the leading cause of nontraumatic lower extremity amputations in the United States Diabetic foot ulcers DFUs are responsible for more hospitalizations than any other diabetic complications Currently even the best available treatments achieve only a healing rate for these wounds and this healing is often only temporary with a chance of recurring Our company has ...

DESCRIPTION provided by applicant The goal of the Phase I study is to determine the feasibility of piloting a low cost Real Time Location System RTLS for use in healthcare based on a novel technology known as Near Field Electromagnetic The proposed QHealth system promises to support a number of healthcare applications such as equipment management workflow optimization hand hygiene complian ...

DESCRIPTION provided by applicant ParaTechs Corporation aims to provide researchers with advanced technology and methods to simplify procedures for laboratory animal models While actively supporting efforts to `reduce replace and refineandapos animal use ParaTechs provides safe and efficient alternatives for surgical procedures We have already brought to market a nonsurgical embryo transfe ...

DESCRIPTION provided by applicant According to the CDC in ischemic heart disease is the leading cause of death worldwide and in the US approximately patients died of ischemic heart disease It is well established in clinical practice that recanalization of he infarct related artery IRA using percutaneous coronary intervention PCI enhances myocardial salvage and outcomes in pa ...