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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A New Technique for Diabetic Foot Ulcers

    SBC: Noveratech LLC            Topic: 200

    ABSTRACT Diabetes is the leading cause of nontraumatic lower extremity amputations in the United States Diabetic foot ulcers DFUs are responsible for more hospitalizations than any other diabetic complications Currently even the best available treatments achieve only a healing rate for these wounds and this healing is often only temporary with a chance of recurring Our company has ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Actuated Low Stress Endotracheal Tube Cleaner to Improve Neonate Lung Function

    SBC: ACTUATED MEDICAL, INC.            Topic: NICHD

    DESCRIPTION provided by applicant This Phase II SBIR finalizes development and clinically tests Neo ET Clear an Actuated Low Stress Endotracheal Tube ETT Cleaner to Improve Neonate Lung Function Neo ET Clear suctions mucus from mm diameter neonatal endotracheal tubes with significantly reduced deleterious impact on lung function and mechanics as compared to current methods includin ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. A mechanism based computational tool to optimize pulmonary drug delivery

    SBC: CFD Research Corporation            Topic: 300

    DESCRIPTION provided by applicant Pulmonary drug delivery has emerged as a noninvasive alternative route for the treatment of lung diseases asthma COPD CF and lung cancer In order to obtain the desired level of effectiveness and safety of the inhaled drugs an appropriate deposition on the targeted region and subsequent absorption in the targeted region is vital Multiscale multidisciplin ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. An Acoustofluidic Device for Point of Care Sputum Processing and Analysis

    SBC: Ascent Bio-Nano Technologies Inc            Topic: NHLBI

    Project Summary Asthma is a chronic lung disease that causes the airways in the lungs to become inflamed making it difficult to breathe and leading to episodes of intense coughing and wheezing The prevalence of asthma has increased rapidly over the past several decades and more than in Americans are now living with the disease While there is no cure for asthma the symptoms of the disease ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Chemical Optimization of a novel class of USP inhibitor for cancer treatment

    SBC: Progenra, Inc            Topic: 102

    DESCRIPTION provided by applicant Numerous regulatory proteins are tightly controlled by ubiquitin conjugation and deconjugation and deviations from this dynamic process are manifested in clinical disorders such as cancer inflammation neurodegenerative disorders and metabolic diseases The deubiquitylase DUB USP plays multiple regulatory roles all of which are pro survival antiapoptotic ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Development of An Integrated High Throughput Imaging and Image Analysis Platform for Muscle

    SBC: CytoInformatics LLC            Topic: NIA

    DESCRIPTION provided by applicant There is growing awareness that weakness of muscle is a significant biomedical health issue associated with many different chronic diseases and aging There are a variety of different diseases that affect muscle including muscular dystrophy fibromyalgia cerebral palsy amyotrophic lateral sclerosis and myasthenia gravis each of which carries its own uniqu ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Development of Tumor Proliferation PET Tracer FLT using a Low Cost Single Dose Automatic Production and Quality Control Biomarker Generator System

    SBC: ABT Molecular Imaging            Topic: 102

    DESCRIPTION provided by applicant Worldwide a person dies from cancer every seconds Positron emission tomography PET is an effective tool that is critical in diagnosing cancer and monitoring treatment efficacy PET imaging relies on use of short lived radioisotopes Commercial distribution of the most commonly used radio tracer F FDG has resulted in patient population coverage in ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Epigenetic Probes for HMTs

    SBC: REACTION BIOLOGY CORPORATION            Topic: 100

    DESCRIPTION provided by applicant Epigenetic proteins such as histone methyltransferases represent important potential drug targets for indications like cancers neurodegenerative disorders and cardiovascular and metabolic diseases At Reaction Biology Corporation andquot RBCandquot we are working toward the complete coverage of all epigenetic targets including HMTs to identify and impr ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Functional Assessment using a Virtual Environment

    SBC: Psychology Software Tools, Inc.            Topic: N

    This Phase II project will develop a computer based tool for the functional assessment of higher level instrumental activities of daily living IADLs using simulated activities in a virtual environment VE IADLs are the high level activities such as managing finances and complex medication regimens and successfully negotiating novel or new situations that are necessary for fully independent liv ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Improving Clinical Encounter Communications to Enhance Minority Diabetes Care

    SBC: Starship Health Technologies, LLC            Topic: NIMHD

    DESCRIPTION provided by applicant Disparities in healthcare delivery and outcomes have been linked in part to the difficulties physicians have in establishing effective communication with patients who differ from themselves in terms of race ethnicity and economic circumstances Type diabetes mellitus and pre diabetic nutrition based obesity are an important case in point Racial and socio ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
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