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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Accelerating Functional Maturation of Human Neurons for High-Throughput Screening

    SBC: BrainXell, Inc            Topic: R43

    Project Summary Abstract Neurological and psychiatric disorders including substance abuse and addiction exert a devastating personal and economic toll on patients families caregivers and society This is in part due to our failures in developing effective medications which in turn to the drug discovery platforms that are often not relevant to target diseases Recent development of induced p ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Accurate protein folding software to predict ligand induced conformational changes in G protein coupled receptors

    SBC: DNASTAR, INC.            Topic: 100

    Abstract In humans and animals G protein coupled receptors GPCRs are embedded on cell surfaces and function as key regulators of physiological events by transmitting signals from extracellular stimulants across the cell membrane into the cell Impaired or abnormal GPCR function can result in disordered physiological processes causing a broad and diverse range of diseases For this reason GPCRs ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. A Formaldehyde Dosimeter for Personal Exposure Assessment

    SBC: Platypus Technologies, LLC            Topic: NIEHS

    DESCRIPTION provided by applicant The air we breathe can contain dozens of toxins The National Institute of Environmental Health Sciences NIEHS strategic plan for includes a major focus on andquot enhancing our ability to quantify individual exposures and responses to environmental toxins andquot Similarly the US Environmental Protection Agency EPA is increasing its emphasis on ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. A mechanism based computational tool to optimize pulmonary drug delivery

    SBC: CFD RESEARCH CORPORATION            Topic: 300

    DESCRIPTION provided by applicant Pulmonary drug delivery has emerged as a noninvasive alternative route for the treatment of lung diseases asthma COPD CF and lung cancer In order to obtain the desired level of effectiveness and safety of the inhaled drugs an appropriate deposition on the targeted region and subsequent absorption in the targeted region is vital Multiscale multidisciplin ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. An Aging Heart Model for Drug Discovery

    SBC: Invivosciences, Inc.            Topic: NIA

    Project Summary Abstract Cardiovascular drugs are primarily prescribed to older peoplertyears of agesince the prevalence of chronic heart failure and fibrillation increases with ageThe incidence of other diseasesincluding cancer and neurological disordersincreases with agetooAny medications hold potential risks to cause adverse eventsThereforethe risks of medications in older people also increase ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. A New Technique for Diabetic Foot Ulcers

    SBC: Noveratech L.L.C.            Topic: 200

    ABSTRACT Diabetes is the leading cause of nontraumatic lower extremity amputations in the United States Diabetic foot ulcers DFUs are responsible for more hospitalizations than any other diabetic complications Currently even the best available treatments achieve only a healing rate for these wounds and this healing is often only temporary with a chance of recurring Our company has ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. A Next Generation, Low Cost Tracking System for Healthcare

    SBC: Q-Track Corporation            Topic: 600

    DESCRIPTION provided by applicant The goal of the Phase I study is to determine the feasibility of piloting a low cost Real Time Location System RTLS for use in healthcare based on a novel technology known as Near Field Electromagnetic The proposed QHealth system promises to support a number of healthcare applications such as equipment management workflow optimization hand hygiene complian ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. An Innovative Device Integrating Cryopreservation, Storage, and Artificial Insemination of Mouse Sperm

    SBC: PARATECHS CORP            Topic: 100

    DESCRIPTION provided by applicant ParaTechs Corporation aims to provide researchers with advanced technology and methods to simplify procedures for laboratory animal models While actively supporting efforts to `reduce replace and refineandapos animal use ParaTechs provides safe and efficient alternatives for surgical procedures We have already brought to market a nonsurgical embryo transfe ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. A Novel Lipotherapy to Reduce Infarct Size Following Myocardial Infarction

    SBC: ENDOPROTECH, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant According to the CDC in ischemic heart disease is the leading cause of death worldwide and in the US approximately patients died of ischemic heart disease It is well established in clinical practice that recanalization of he infarct related artery IRA using percutaneous coronary intervention PCI enhances myocardial salvage and outcomes in pa ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. A Predictive In Vitro Model for Screening Personalized Responses to CFTR-directed Therapeutics

    SBC: CFD RESEARCH CORPORATION            Topic: NHLBI

    Abstract The objective of this study is to develop a novel predictive in vitro model for personalized responses to CFTR directed therapeutics This proposal responds to RFA HL Human Cellular Models for Predicting Individual Responses to Cystic Fibrosis Transmembrane Conductance Regulator Directed Therapeutics Cystic fibrosis CF is a life shortening genetic disease caused by loss of ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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