Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. A New Technique for Diabetic Foot Ulcers

    SBC: Noveratech LLC            Topic: 200

    ABSTRACT Diabetes is the leading cause of nontraumatic lower extremity amputations in the United States Diabetic foot ulcers DFUs are responsible for more hospitalizations than any other diabetic complications Currently even the best available treatments achieve only a healing rate for these wounds and this healing is often only temporary with a chance of recurring Our company has ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. A Novel Pharmacological Treatment for Neuropathic Pain

    SBC: Aptinyx Inc            Topic: 105

    PROJECT SUMMARY Neuropathic pain NP conditions affect up to of the population while the annual costs of treatment reach $ billion in the US Pain reduction is more difficult to achieve in NP since the mechanisms involved are not the same as the mechanisms of normal nociceptive pain Current therapeutic approaches offer limited pain relief and frequently produce side effects that outweig ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. A Proton Radiography System for Optimization of Proton Therapy

    SBC: ProtonVDA LLC            Topic: 102

    Proton radiography produces images of patients in terms of proton stopping power by tracking individual protons before and after the patient and measuring the proton residual range after traversing the patient and would be the most direct method of image guidance for proton radiation therapy Radiation therapy is needed for more than of the million Americans who are annually diagnosed wi ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. A mechanism based computational tool to optimize pulmonary drug delivery

    SBC: CFD Research Corporation            Topic: 300

    DESCRIPTION provided by applicant Pulmonary drug delivery has emerged as a noninvasive alternative route for the treatment of lung diseases asthma COPD CF and lung cancer In order to obtain the desired level of effectiveness and safety of the inhaled drugs an appropriate deposition on the targeted region and subsequent absorption in the targeted region is vital Multiscale multidisciplin ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Aminomethyl benzamides as novel anti Ebola agents

    SBC: Chicago Biosolutions, Inc.            Topic: NIAID

    Ebola EBOV and Marburg MARV viruses belong to the family Filoviridae and can cause fatal hemorrhagic fevers characterized by widespread tissue destruction with an incubation period of days Because of the safety concerns these viruses are designated as the biosafety level agents Currently there is no effective vaccine or therapeutic treatment against filoviral infection and pathogenes ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Aminopiperidines as novel anti influenza agents

    SBC: Chicago Biosolutions, Inc.            Topic: NIAID

    Influenza A viruses belong to the orthomyxoviridae family with a negative sense segmented RNA genome which can cause seasonal or pandemic flu with high morbidity and significant mortality Vaccination is the most prevalent prophylactic means for controlling influenza infections However an effective vaccine usually takes at least months to develop for the circulating strains Furthermore vac ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. An Ultra filtrate perfusion bio artificial pancreas for high-density islet replacement without immunosuppression

    SBC: Norfolk Medical Products, INC.            Topic: NIDDK

    DESCRIPTION provided by applicant The Cell SafeTM is a fundamentally new approach in replacement of dysfunctional insulin producing cells in patients with diabetes by transplantation of new islets in a three dimensional scaffold embedded in a highly compatible bioengineered perfusion system that continuously supplies tissue fluid blood ultrafiltrate so that the cells ae protected from immun ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Better Living After Stroke through Technology (BLAST)

    SBC: BRIGHTOUTCOME INC.            Topic: 600

    DESCRIPTION provided by applicant Stroke the leading cause of disability cognitive impairment and death in the US imposes significant financial and personal burden The residual effects of stroke affect many aspects of life not addressed by traditional rehabilitation treatments In particular persons with mild stroke typically defined as a stroke with no or sligh motor impairment and a high ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Better Living After Stroke through Technology BLAST

    SBC: BRIGHTOUTCOME INC.            Topic: 600

    DESCRIPTION provided by applicant Stroke the leading cause of disability cognitive impairment and death in the US imposes significant financial and personal burden The residual effects of stroke affect many aspects of life not addressed by traditional rehabilitation treatments In particular persons with mild stroke typically defined as a stroke with no or sligh motor impairment and a high ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Buccal Nanocytological Risk Stratification to Personalize Lung Cancer Screening

    SBC: NANOCYTOMICS LLC            Topic: 102

    Project Summary Abstract This goal of this SBIR project is to develop a commercial grade Nanocytology system for FDA clinical trials and subsequent commercialization of a lung cancer risk stratification test to personalize lung cancer screening Lung cancer is the leading cause of cancer deaths in the U S The reason for the lethality of lung cancer relates to its tendency to be diagnosed at a lat ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
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