Award Data

DESCRIPTION (provided by applicant): The proposed effort aims to dramatically enhance the realism of radiation safety training for Emergency Responders, both First Responders, as well as Skilled Support Personnel. The goal is to develop andevaluate realistic dosimetry simulation or Dosimulation tools. These Realistic, Accurate Dosimulation (RAD) tools will be the centerpiece for ...

DESCRIPTION provided by applicant Type diabetes T D is a chronic disease caused by the autoimmune destruction of the insulin producing beta cells in the pancreas Current treatment options for T D are severely limited All patients diagnosed with T DM are placed on life long insulin therapy and the current standard of care for adult patients with T DM is intensive diabetes therapy to avoid ...

DESCRIPTION: Pulmonary drug delivery is increasingly used for both treatment of lung diseases (such as asthma and chronic obstructive pulmonary disease) and in delivering drugs to the systemic circulation. To reach the desired effectiveness and safety oforally/nasally inhaled drugs, appropriate deposition of drugs on targeted region is essential. Due to complex pharmaceutical and physiological fa ...

DESCRIPTION (provided by applicant): With the increased use of x-ray CT, the development of a market for CT screening exams, and the imaging of younger patients, there is a growing concern about the public health risk caused by the radiation dose deliveredby x-ray CT. The reduction of this dose has therefore taken on increased importance, as evidenced by the recent NIH Summit on Managing Dose in C ...

DESCRIPTION (provided by applicant): The baculovirus expression vector system (BEVS) has been successfully utilized to produce thousands of proteins for use as vaccines, therapeutics, and for structure-function studies. One limitation of BEVS is the propensity of baculoviruses to accumulate transposon insertions into the fp25k gene leading to the few polyhedra (FP) phenotype. This mutation shift ...

DESCRIPTION (provided by applicant): There is an acute need for the development of a new class of selective and sensitive portable analytical sensors to enable reliable monitoring of multiple classes of chemical analytes in complex biomatrices. Current preferred methods for determining the concentration of analytes are spectroscopy and voltammetry. We propose the development of electrochemical m ...

DESCRIPTION provided by applicant Low vision rehabilitation is the only proven way to restore functional vision and maintain a high quality of life in patients with permanent vision impairment Low vision aids are devices that manipulate visual information for example magnify images to compensate for impaired vision The patientandapos s willingness to accept a low vision aid ability to ada ...

In 2011, there were 60,000 dairy farms in the US. Of there, 56,600 had herds of fewer than 500 animals. Currently, manure digester installations are only considered economical for herds of at least 500 animals. There require turbine or diesel generator sets of 100 Kilowatt size and larger. The need exists for a smaller waste to energy conversion approach for implementation on small farms were ...

The primary goal of this proposed work is to develop a long wave infrared (LWIR) colloidal quantum dot (CQD)-based focal plane array (FPA) in order to significantly reduce the cost of LWIR hyperspectral imagers. In order to realize this goal, it will first be necessary to successfully fabricate and demonstrate the performance of novel LWIR HgTe CQD detector arrays. This will be accomplished thro ...

DESCRIPTION provided by applicant Pulmonary drug delivery has emerged as a noninvasive alternative route for the treatment of lung diseases asthma COPD CF and lung cancer In order to obtain the desired level of effectiveness and safety of the inhaled drugs an appropriate deposition on the targeted region and subsequent absorption in the targeted region is vital Multiscale multidisciplin ...