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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Bioactive Nanofibrous Sewing Cuff for Treatment of Cardiac Valvular Disease

    SBC: BIOSURFACES INC            Topic: NHLBI

    PROJECT SUMMARY Cardiac valve repair or replacement is indicated when progression of degenerative disease or bacterial infection of the native valve results in valvular dysfunction, thereby impacting cardiac output. Both procedures require the use of a woven or knitted polyester material with an internal reinforcement (Teflon, silicone or metal) to either stabilize the native valve (annuloplasty r ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. A Compact, High-power Terahertz Amplifier for DNP-NMR and EPR Spectroscopy

    SBC: BRIDGE 12 TECHNOLOGIES, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): We propose to develop a compact, cost-effective Traveling Wave Tube (TWT) amplifier at 263 GHz with 50 W of peak power, 5 W of continuous wave power and 5% instantaneous bandwidth for application in Dynamic Nuclear Polarization (DNP) enhanced solid-state and solution-state NMR and Electron Paramagnetic Resonance (EPR) spectroscopy. With DNP, the inherently smal ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Acoustic lysis and extraction system for limited cell number applications

    SBC: COVARIS, INC.            Topic: 200

    DESCRIPTION provided by applicant Analysis of single cells or cells that are not present in large numbers in the body is important to understanding basic biology and diseases A specific example is cancer in which changes in DNA in a single cell can lead to that cell reproducing rapidly Similarly studying the proteins that make up these cells can tell us how the changes in DNA result in ch ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. ACOUSTOPHORETIC TRANSFUSION TO REDUCE EMBOLIZATION IN CARDIOPULMONARY BYPASS

    SBC: Flodesign Sonics, Inc.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Retransfusion of a patient's shed blood during cardiopulmonary bypass is attractive since it reduces the need for allogeneic transfusion, minimizes cost, and decreases transfusion related morbidity. Heterologous transfusions are linked to increased long term mortality after cardiac surgery. However, brain damage after cardiac surgery with retransfusion of ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. A Culture-Free Platform for Rapid Pathogen Identification

    SBC: HELIXBIND, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): A Culture-Free Platform for Rapid Pathogen Identification Project Summary Sepsis is a one of the leading causes of morbidity and mortality in the US, with more than 751,000 confirmed cases occurring every year and 210,000 mortalities. This high mortality rate (~30%) means that nearly 600 patients a day succumb to sepsis-related infections. In addition to the hu ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Acute Pancreatitis: Renalase as a novel target and agonists as new therapy

    SBC: BESSOR PHARMA, LLC            Topic: 300

    Project Summary Abstract This proposal brings together a top team with diverse and complementary expertise to develop a novel therapeutic agent based on a newly described serum protein renalase RNLS to treat acute pancreatitis AP This protein appears to have a novel protective effect in models of acute tissue injury including AP AP affects more than people year in the USA and can c ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Adaptive Optics OCT/Fluorescence Small Animal Imager

    SBC: PHYSICAL SCIENCES INC.            Topic: NEI

    DESCRIPTION (provided by applicant): Physical Sciences Inc. proposes to develop a new, integrated multimodal adaptive optics small animal imager, including AO-OCT and AO scanning laser fluorescence (fAOSLO), and to demonstrate its applications to detectingpathology in the retinas of rodent models of eye disease. The imaging platform includes novel design elements such as adaptable wavefront sensin ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Adolescent Screener and Opioid Assessment for Patients with Pain (A-SOAPP)

    SBC: Inflexxion, Inc.            Topic: NIDA

    DESCRIPTION (provided by applicant): Pain management including the use of opioid analgesics is recommended for adolescents who are suffering from recurrent or chronic pain associated with a specific etiology such as cancer, cystic fibrosis, sickle cell anemia, hemophilia or organ transplants (see citations by etiology in letter of support from CO-I, Dr. Solodiuk). Preventive screening tools provi ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Advanced LWIR Hyperspectral System for On-the-Move Standoff Detection of Liquid and Solid Contaminants on Surfaces

    SBC: PHYSICAL SCIENCES INC.            Topic: CBD12104

    Physical Sciences Inc. (PSI) proposes to utilize an innovative LWIR hyperspectral technology coupled with advanced data processing algorithms for non-contact, standoff detection of liquid/solid contaminants on surfaces. The technology will address the US Army"s need for fast, on-the-move, non-contact detection of ground contamination during reconnaissance missions. The Phase I effort demonstrated ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  10. Advancing a Mucosal HSV-2 Vaccine Towards Clinical Trials

    SBC: Biomedical Research Models, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Globally, an estimated 16.2% of the human population is infected with HSV-2 including gt17% of the U.S. adult population. Genital herpes is associated with an increased risk of HIV acquisition and transmission and HSV-2infection can cause neonatal herpes with high infant mortality. HSV-2 infection in the adult population has increased substantially in the past ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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