Award Data

Project Summary The objective of this Phase I SBIR proposal is to demonstrate the feasibility of a device designed to connect two small vessels together simply and easily and that would replace the hand suturing technique currently used to connect vessels in microsurgery and macrovascular end to end vascular repair surgeries This completely biodegradable vascular coupling device VCD being devel ...

The broad long term objective and specific aims of the fast track SBIR research are to create a reagent RecombiRED for use in microinjection of embryos for identifying a subset of embryos as recombination competent injections The ability to quickly identify genome editing events in an embryo allows researcher to quickly make precision animal models of human disease states Precise animal m ...

This work advances the state-of-the-art in high-speed diagnostics for the characterization of fireballs, hot gases, and aerosols released by explosives detonation.The proposed advancement is the development of an integrated optical sensor suite, selected from technologies which are already in development in the portfolio of the proposers.The sensor suite will include PIV, PLIF, and LIBS instrument ...

DESCRIPTION provided by applicant Pulmonary drug delivery has emerged as a noninvasive alternative route for the treatment of lung diseases asthma COPD CF and lung cancer In order to obtain the desired level of effectiveness and safety of the inhaled drugs an appropriate deposition on the targeted region and subsequent absorption in the targeted region is vital Multiscale multidisciplin ...

Abstract Alzheimerandapos s disease AD is one of the leading causes of death among aged people and currently more than million people have AD in the US alone Although there is no cure for AD studies indicate that clinically proven medicines have the ability to slow ADandapos s progress especially if they are administered early on Obviously to develop diagnostics that are able to detect ...

DESCRIPTION provided by applicant The objective of this SBIR Phase I project is to develop a novel sequence specific capture SSC technology to quantitatively and robustly retrieve circulating miRNAs from blood which can transform the utility of circulating miRNAs testing in diagnosis of diseases including cancer and cardiovascular disease Circulating miRNAs have emerged as novel biomarkers ...

ABSTRACT Diabetes is the leading cause of nontraumatic lower extremity amputations in the United States Diabetic foot ulcers DFUs are responsible for more hospitalizations than any other diabetic complications Currently even the best available treatments achieve only a healing rate for these wounds and this healing is often only temporary with a chance of recurring Our company has ...

DESCRIPTION provided by applicant The goal of the Phase I study is to determine the feasibility of piloting a low cost Real Time Location System RTLS for use in healthcare based on a novel technology known as Near Field Electromagnetic The proposed QHealth system promises to support a number of healthcare applications such as equipment management workflow optimization hand hygiene complian ...

DESCRIPTION provided by applicant ParaTechs Corporation aims to provide researchers with advanced technology and methods to simplify procedures for laboratory animal models While actively supporting efforts to `reduce replace and refineandapos animal use ParaTechs provides safe and efficient alternatives for surgical procedures We have already brought to market a nonsurgical embryo transfe ...

DESCRIPTION provided by applicant According to the CDC in ischemic heart disease is the leading cause of death worldwide and in the US approximately patients died of ischemic heart disease It is well established in clinical practice that recanalization of he infarct related artery IRA using percutaneous coronary intervention PCI enhances myocardial salvage and outcomes in pa ...