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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Commercialization of a Simple Automatic Perfusion System for ECPR

    SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC.            Topic: NHLBI

    DESCRIPTIONprovided by applicantThe use of ECMO in conjunction with CPRa technique known as "ECPR"has been shown to reduce central nervous systemCNSdamageimprove brain function after recoveryand result in survival to hospitaldischarge rates up toA limiting factor for widespread adoption of ECPR is the need for a simple automatic perfusion system that is inherently safeand provides full support wit ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Broad Spectrum Antiviral Nucleoside Phosphonate Analogs

    SBC: TSRL, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The Working Group for Civilian Biodefense reviewed potential biological threat agents and listed those considered to pose the greatest threat to the civilian population Variola and other orthopox DNA viruses were identified as a potential bioterrorism threat Additionally other DNA viruses are of increasing concern in a public health context due to the emerge ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Improving Outcomes for Mechanically Ventilated Patients with the Digital EZ Board

    SBC: VIDATAK, LLC            Topic: 600

    DESCRIPTION provided by applicant Effective communication between patients and healthcare professionals is essential to achieve positive clinical outcomes Patients who are unable to communicate effectively e g patients with limited English proficiency LEP those who are hearing impaired aphasic or have oral tracheal intubation experience extreme frustration panic anxiety sleeplessne ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Development of DT-110 as an oral therapeutic for type 2 diabetes

    SBC: Diapin Therapeutics LLC            Topic: 200

    DESCRIPTION provided by applicant Type diabetes is a chronic debilitating disease that threatens to reach pandemic level by Nearly million people worldwide are currently affected by diabetes and more than of patients with type diabetes die of cardiovascular causes However no particular diabetes medication to date is considered superior in the minimization of the risk of card ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Image-Guided Transurethral HIFU for Genitourinary Therapy

    SBC: ACOUSTIC MEDSYSTEMS, INC.            Topic: 400

    DESCRIPTION provided by applicant Stress urinary incontinence SUI in women is an increase of pelvic floor compliance which results in decrease of urethral pressure typically through childbirth and presents as urine leakage during exertion SUI has significant impact on womenandapos s health including an association with increased levels of depression Curative options are limited to the in ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Advanced Nitric Oxide Release Bactericidal Urinary Catheters

    SBC: BIOCREDE INC.            Topic: 300

    DESCRIPTION provided by applicant In Phase I Biocrede developed a completely new urinary tract silicone Foley catheter with a andgt month shelf life made from a proprietary polymeric formulation to effectively reduce catheter associated urinary tract infections CAUTI via nitric oxide NO release for andgt weeks Key features of the new technology include catheters continuously d ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  7. A Force-controlled Probe Based Platform for Single-Cell Biomolecular Delivery

    SBC: INFINITESIMAL, LLC            Topic: 100

    DESCRIPTION provided by applicant This proposed Phase II project will lead to a commercial product capable of transfecting individual target cells This new biotool uses a patented microfabricated chip called a nanofountain probe NFP to deliver molecules into live individual target cells by single cell electroporation which induces temporary nanopores in the cell membrane via the applicat ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Quantitative Optical Assessment of Middle Ear Disease

    SBC: PHOTONICARE INC            Topic: NIDCD

    DESCRIPTION provided by applicant PhotoniCare Inc is a medical device company developing a handheld biophotonics imaging system suitable for use by otolaryngologists ear nose and throat specialists ENT and primary care physicians PCP to enable real time D assessment of sub surface tissue structure in the middle ear Significance ENTs and PCPs have limited tools with which to diagn ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Model-Based Software for Configuring Switch Scanning Systems

    SBC: Koester Performance Research            Topic: NICHD

    DESCRIPTION provided by applicant Model Based Software for Configuring Switch Scanning Systems The overall goal of this work is to improve outcomes for people who use switch scanning Switch scanning is used by individuals with severe motor and speech impairments as a method for entering text and data into computers and augmentative communication devices The text entry rate TER with scannin ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  10. High-yield production of GDP-fucose for fucosylation of molecules

    SBC: ZUCHEM INC.            Topic: 300

    DESCRIPTION provided by applicant Fucosylation plays an important role in many cellular processes Fucosylated oligosaccharides in the cell are involved in many biochemical recognition processes microbial infections toxin entry and cancer cell metastasis These properties make fucosylated molecules valuable for pharmaceutical and drug discovery needs but current production methods are very ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
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