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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Nucleic acid delivery of growth factors and heparan sulfate proteoglycans for enh

    SBC: International Medicine and Biomedical Research            Topic: NIAMS

    DESCRIPTION (provided by applicant): In chronic wounds, numerous factors contribute to the diminished healing. Wound healing constituents, including heparan sulfate proteoglycans and numerous growth factors, are essential to normal skin wound healing. Several key growth factors such as FGF, VEGF, and PDGF require heparan sulfate-like polymers as co- receptors or co-activators for growth factor act ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  2. Development of recombinant rhTL1A protein for cancer treatment

    SBC: BIOPOWERTECH            Topic: NCI

    DESCRIPTION (provided by applicant): Breast cancer is the most common cause of cancer in women and the second most common cause of cancer death in women in the United States. In 2009, approximately 40,170 women in the US are estimated to die from breast cancer. In most cases, death results from metastasis of breast cancer cells. Cancer patients with metastasis cannot currently be cured. Therefore, ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. Characterization and Mitigation of Radiation Effects in Quantum Dot Based Nanotechnologies

    SBC: CFD RESEARCH CORPORATION            Topic: DTRA082001

    For applications in DoD satellite systems, devices based on novel nanomaterials offer significant advantages over traditional technologies in terms of light-weight and efficiency. Examples of such novel devices include quantum dot (QD) based solar cells, photodetectors, radars and sensors. However, the response of these devices to radiation effects is not well understood, and radiation effects mod ...

    SBIR Phase II 2010 Department of DefenseDefense Threat Reduction Agency
  4. Characterization and Mitigation of Radiation Effects in Nonplanar Nano-technology Microelectronics

    SBC: CFD RESEARCH CORPORATION            Topic: DTRA092001

    Future high-performance integrated circuits in DoD satellite systems will require non-planar nano-technology devices, such as MultiGate Field Effect Transistors (MuGFET) or FinFET, which can decrease pattern area of logic circuits below 50% of the conventional planar technologies. The International Technology Roadmap for Semiconductors predicts that such devices will be the cornerstone of sub-32nm ...

    SBIR Phase I 2010 Department of DefenseDefense Threat Reduction Agency
  5. An Integrated, Electrokinetics-Augmented Microfluidic Device for Forensic DNA Analysis

    SBC: CFD RESEARCH CORPORATION            Topic: DTRA092003

    The use of WMDs and IEDs by covert insurgents and terrorists poses a significant risk to U.S. military forces and civilians. The capability to execute rapid forensic DNA analysis to identify individuals who manufactured and transported these threatening devices is of paramount importance to military mission, homeland security and civilian safety. Current DNA forensic analyses are time-consuming, b ...

    SBIR Phase I 2010 Department of DefenseDefense Threat Reduction Agency
  6. A Nanofluidic Nanoplasmonic Platform for Multiplexing Detection of Cancer Biomark

    SBC: CFD RESEARCH CORPORATION            Topic: NCI

    DESCRIPTION (provided by applicant): This project aims to develop a novel nanofluidic-nanoplasmonic platform to realize multiplexed monitoring of biological binding processes, specifically for detection of cancer biomarkers in bio-fluids. In contrast to current large-sized, cumbersome surface plasmon resonance (SPR) sensing technology, the proposed device is comprised of a multilayer nanostructure ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  7. Electrokinetic-based Microfluidic Universal Sample-Preparation (EMUS) Platform

    SBC: CFD RESEARCH CORPORATION            Topic: DTRA092002

    Sample preparation has been recognized as the single most important challenge to be faced in the development of detect-to-warn (DTW) systems. Available commercial sample preparation technologies are expensive, slow, and require trained laboratory technicians and sophisticated laboratory equipment for operation. Addressing this need, we propose to design, fabricate, and demonstrate a general purpos ...

    SBIR Phase I 2010 Department of DefenseDefense Threat Reduction Agency
  8. Discovery of Inhibitors of PTH-Wnt Signaling Synergy in Bone Cells

    SBC: DISCOVERYBIOMED, INC.            Topic: NIAMS

    DESCRIPTION (provided by applicant): Project Summary Description Title: Discovery of Inhibitors of PTH-Wnt Signaling Synergy in Bone Cells. Osteoporosis is a growing problem in the aged and an unfortunately large disease market and burden to the healthcare industry. This debilitating disease costs 18 billion in healthcare costs annually in the US and affects 10 million people in the US and an est ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  9. Fluorescence Anisotropy-based Macromolecule Crystallization Screening

    SBC: iXpressGenes, Inc.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Current practice is to set up trial crystallization screens and periodically review the results to see if a crystal or promising crystal-like precipitate has appeared a process that often takes weeks or months. Most outcomes are precipitated protein or clear drops, and the conditions that led to those results are removed from further consideration. We are deve ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  10. New In Vitro Human Liver Toxicity Bioassay System

    SBC: Vivo Biosciences Inc            Topic: NIEHS

    DESCRIPTION (provided by applicant): Abstract: The overall goal of this SBIR proposal is to develop and commercialize a new human liver bioassay system for real time, long-term toxicity analysis of chemical agents or drugs in vitro. At present, liver studies are mostly performed using hepatocytes cultured onto synthetic or animal-derived matrices. Unfortunately these models fail to replicate true ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
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