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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. MASS PRODUCTION OF PERSONALIZED HUMAN ENGINEERED HEART TISSUES

    SBC: Invivosciences, Inc.            Topic: 200

    DESCRIPTION provided by applicant Cardiomyopathy has various forms including hypertrophic cardiomyopathy HCM in prevalence could cause sudden cardiac death in athletes Dilated Cardiomyopathy DCM in prevalence results in an enlarge left ventricle Arrhythmogenic Right Ventricular Dysplasia Cardiomyopathy ARVD C in prevalence causes cardiac fibrosis Yearly over $ ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Electronics and computational hardware for ultra-high channel count electrophysio

    SBC: Leaflabs, LLC            Topic: 101

    DESCRIPTION provided by applicant The advent of in vivo multielectrode recording has indicated the importance of recording from large populations of neurons As a result there is much interest in creating new kinds of in vivo multielectrode arrays including the polytrode new kinds of microfabricated electrode arrays and new kinds of ultradense D electrode array And yet innovation on the ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Fluorescence Lifetime Dynamics to Understand Brain Neural Activities and Behavior

    SBC: ChiSquare Bioimaging, LLC            Topic: 500

    DESCRIPTION provided by applicant The overall objective of the proposed project is to create a compact robust and easy to use device that is capable of sensitive and quantitative detection of fluorescence lifetime indicators of physiological and biochemical dynamics deep in the brain of a freely moving mouse In contrast to fluorescence intensity based methods fluorescence lifetime can delin ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Optopatch: high-throughput all-optical electrophysiology for neural recording

    SBC: Q-State Biosciences, Inc.            Topic: 102

    DESCRIPTION provided by applicant Optopatch high throughput all optical electrophysiology for neural recording The convergence of stem cell genomic and advanced imaging technologies provides unprecedented ability to study human neural physiology in health and disease Traditionally intractable diseases schizophrenia autism Alzheimerandapos s ALS and Parkinsonandapos s are being modeled ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Transitioning Electronic Support for Public Health (ESP) from Lab to Marketplace

    SBC: Commonwealth Informatics, Inc.            Topic: 400

    DESCRIPTION provided by applicant Accurate and complete disease surveillance is critical to enable public health authorities to detect and respond to disease outbreaks epidemics and even bioterrorism events While legally required of healthcare practitioners and practices most notifiable disease reporting is still done manually or through limited automated laboratory test result reporting ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Aptamer-Based Detection of Cardiac Biomarker Glycosylation States Using APT-SNAP

    SBC: Proteovista LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Aptamer Based Detection of Cardiac Biomarker Glycosylation States Using APT SNAP Arrays PIs Christopher L Warren and Mary S Ozers The presence of cardiac related biomarkers in patient biospecimens can provide important insight into diagnosis of cardiovascular disease its progression and optimal therapies for treatment Most of the cardiac biomarkers in cli ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a novel highly effective influenza vaccine

    SBC: Flugen, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Seasonal influenza flu virus an NIAID category C priority pathogen causes widespread infection resulting in at least million cases of severe illness and deaths worldwide Young children and elderly or immunocompromised individuals are typically at greater risk of severe illness or death from influenza Newly emerging strains can result ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. New heterocyclic inhibitors of filoviruses

    SBC: MICROBIOTIX, INC.            Topic: H

    DESCRIPTION provided by applicant Ebola and Marburg viruses belong to the family Filoviridae and can cause fatal hemorrhagic fevers characterized by widespread tissue destruction with an incubation period of days Because of the safety concerns these viruses are designated as the biosafety level agents Currently there is no effective vaccine or therapeutic treatment against filoviral i ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Nitric Oxide Microfluidic Sensor

    SBC: CLINICAL SENSORS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant This Small Business Innovation Research SBIR Phase I project aims to develop a microfluidic based nitric oxide NO sensor as an early sepsis risk assessment device Sepsis causes significant strain on the U S healthcare system consuming over $ billion annually due to extended hospital stays and significant morbidity and mortality Rapid diagnosis and in ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. XRpro Radioactive Cesium Decorporation Agents

    SBC: Icagen, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Caldera aims to develop an inexpensive stable selective decorporation decorp agent for cesium Cs Cs is easily obtainable by terrorists and treatments for exposures are Project Bioshield priorities for use in radiation nuclear emergencies high priority for DHHS NIH NIAID DAIT and a critical need for the Strategic National Stockpile S ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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