Award Data

DESCRIPTION (provided by applicant): Available methods for molecular structure determination, based primarily on x-ray crystallography and Nuclear Magnetic Resonance (NMR) solution methods, have had limited success on the insoluble proteins that are critical to biological function. Various recent developments have enhanced the effectiveness of solids NMR methods incorporating Magic Angle sample Sp ...

DESCRIPTION (provided by applicant): According to the American Diabetes Association, there are more than 16 million people in the United States with known diabetes. Diabetic patients commonly demonstrate impaired wound healing. Approximately 20 percent of patients with diabetes will develop foot ulceration in their lifetime. Diabetic foot ulceration (DFU) represents a major problem that can signif ...

Not Available

Project Summary/Abstract According to the ADA, 25.8 million children and adults have diabetes. Diabetics have an increased risk of complications such as heart disease and are prone to impaired wound healing. A major cause of morbidity and hospitalizationis diabetic foot ulceration (DFUs) that may result in infection, gangrene, amputations requiring prolonged hospitalization, costly treatments, an ...

DESCRIPTION provided by applicant Some of the most significant therapies that treat disease target nucleic acids Drugs that target nucleic acid include cancer drugs antibiotics and antivirals Combined these classes of drugs have annual sales worldwide of $ billion Antibiotics that target nucleic acids account for $ billion of the $ billion of sales annuall for all antibiotics an ...

DESCRIPTION provided by applicant Self monitoring has been described as the andquot cornerstone of the behavioral treatment of obesityandquot Consistent self monitoring of energy intake is associated with improved dietary adherence and weight loss and maintenance The problem is that individuals are notoriously bad at self monitoring their intake and suffer from an underreporting bias The s ...

DESCRIPTION provided by applicant Heart attacks i e myocardial infarction or MI occur in more than million patients annually Advances in pharmacological therapy have dramatically improved survival following the initial MI Consequently the number of patients with previous MI continues to increase and as a result put in jeopardy millions of patients for development of heart failure I ...

DESCRIPTION provided by applicant Nearly half of all college students have a diagnosable mental health problem Blanco et al College counseling centers CCCs are faced with increasing demands for services from Universities students and parents to meet the treatment needs of their students Kay and Schwartz in the context of increasingly severe cases and declining resources ...

DESCRIPTION provided by applicant The mission of CarboNix LLC is the clinically effective abatement of common indoor allergens that cause allergic reactions and frequently induce asthma especially in economically disadvantaged children CarboNix LLC proposes a Phase II SBIR research program that will result in commercialization of a new service business for abating multiple indoor allergens k ...

DESCRIPTION provided by applicant According to the ADA million children and adults have diabetes Diabetics have an increased risk of complications such as heart disease and are prone to impaired wound healing A major cause of morbidity and hospitalization is diabetic foot ulceration DFUs that may result in infection gangrene amputations requiring prolonged hospitalization costly tr ...